Cyclosporin partitions into phospholipid vesicles and disrupts membrane architecture

Immunology Letters

Volumn 11, Issue 5-6, 1985, Pages 343-349

  Haynes, Mark ^a   Fuller, Laphalle ^a   Haynes, Duncan H ^a   Miller, Joshua ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

cyclosporin; hydrophobic interactions; lipid vesicles

Indexed keywords

8 ANILINO 1 NAPHTHALENESULFONIC ACID; CONCANAVALIN A; CYCLOSPORIN; CYCLOSPORIN A; RADIOISOTOPE;

B LYMPHOCYTE; DIHYDROCYCLOSPORIN C H 3; DOSE RESPONSE; DRUG BINDING; DRUG MECHANISM; DRUG RESPONSE; HUMAN; HUMAN CELL; LYMPHATIC SYSTEM; MEMBRANE FLUIDITY; MONONUCLEAR CELL; PHOSPHOLIPID VESICLE; PRIORITY JOURNAL; RETICULOENDOTHELIAL SYSTEM; T LYMPHOCYTE;

CONCANAVALIN A; CYCLOSPORINS; ERYTHROCYTES; HUMAN; KINETICS; LIPOSOMES; MONOCYTES; PHOSPHATIDYLCHOLINES; RECEPTORS, IMMUNOLOGIC; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.; T-LYMPHOCYTES; TRITIUM;

EID: 0022340275     PISSN: 01652478     EISSN: None     Source Type: Journal    
DOI: 10.1016/0165-2478(85)90118-X     Document Type: Article

References (33)

1. Detection of ionophore-cation complexes on phospholipid membranes
2. The Physical Properties of Phospholipids. I. Solid State and Mesomorphic Properties of Some 2,3-Diacyl-DL-Phosphatidylethanolamines