Cachectin/tumor necrosis factor stimulates collagenase and prostaglandin E2 production by human synovial cells and dermal fibroblasts

Journal of Experimental Medicine

Volumn 162, Issue 6, 1985, Pages 2163-2168

  Dayer, J M ^a   Beutler, B ^b   Cerami, Argo A ^b  

^a GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^b ROCKEFELLER UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; COLLAGENASE; INTERLEUKIN 1; LIPOPOLYSACCHARIDE; PROSTAGLANDIN E2; TUMOR NECROSIS FACTOR;

CARTILAGE; DOSE RESPONSE; DRUG COMPARISON; DRUG MECHANISM; DRUG RESPONSE; FIBROBLAST; HUMAN; HUMAN CELL; IN VITRO STUDY; JOINT; MONONUCLEAR CELL FACTOR; PRIORITY JOURNAL; SYNOVIOCYTE;

ANIMAL; DINOPROSTONE; FIBROBLASTS; GLYCOPROTEINS; HUMAN; INTERFERON TYPE I; INTERLEUKIN-1; MICE; MICROBIAL COLLAGENASE; MONOKINES; PROSTAGLANDINS E; PROTEINS; RECOMBINANT PROTEINS; SKIN; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; SYNOVIAL MEMBRANE; TUMOR NECROSIS FACTOR;

EID: 0022296893     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.162.6.2163     Document Type: Article

References (26)

1. Beisel, W. R. 1975. Metabolic response to infection. Annu. Rev. Med. 26: 9.
2. Filkins, J. P. 1985. Monokines and the metabolic pathophysiology of septic shock. Fed. Proc. 44: 300.
3. Filkins, J. P. 1981. The reticuloendothelial system and metabolic homeostasis. In Pathophysiology of the reticuloendothelial system. B. M. Altura and T. M. Saba, editors. Raven Press, New York. 93.
4. Beutler, B., J. Mahoney, N. Le Trang, P. Pekala, and A. Cerami. 1985. Purification of cachectin, a lipoprotein lipase-suppressing hormone secreted by endotoxin-induced RAW 264.7 cells. J. Exp. Med. 161: 984.
5. Beutler, B., D. Greenwald, J. D. Hulmes, M. Chang, Y.-C. E. Pan, J. Mathison, R. Ulevitch, and A. Cerami. 1985. Identity of tumour necrosis factor and the macrophage- secreted factor cachectin. Nature (Lond.). 316: 552.
6. Carswell, E. A., L.J. Old, R. L. Kassel, S. Green, N. Fiore, and B. Williamson. 1975. An endotoxin-induced serum factor that causes necrosis of tumors. Proc. Natl. Acad. Sci. USA 72: 3666.
7. Aggarwal, B. B., W. J. Kohr, P. E. Hass, B. Moffat, S. A. Spencer, W.J. Henzel, T. S. Bringman, G. E. Nedwin, D. V. Goeddel, and R. N. Harkins. 1985. Human tumor necrosis factor. Production, purification, and characterization. J. Biol. Chem. 260: 2345.
8. Pennica, D., G. E. Nedwin, J. S. Hayflick, P. H. Seeburg, R. Derynck, M. A. Palladino, W.J. Kohr, B. B. Aggarwal, and D. V. Goeddel. 1984. Human tumor necrosis factor:precursor structure, expression and homology to lymphotoxin. Nature (Lond.). 312: 724.
9. Mahoney, J. R., B. A. Beutler, N. Le Trang, W. Vine, Y. Ikeda, M. Kawakami, and A. Cerami. 1985. Lipopolysaccharide-treated RAW 264.7 cells produce a mediator which inhibits lipoprotein iipase in 3T3-L 1 cells. J. Immunol. 134: 1673.
10. Torti, F. M., B. Dieckmann, B. Beutler, A. Cerami, and G. M. Ringold. 1985. A macrophage factor inhibits adipocyte gene expression: an in vitro model of cachexia. Science (Wash. DC). 229: 867.
11. Beutler, B., I. W. Milsark, and A. Cerami. 1985. Passive immunization against cachectin/tumor necrosis factor (TNF) protects mice from the lethal effect of endotoxin. Science (Wash. DC). 229: 869.
12. Cerami, A., Y. Ikeda, N. Le Trang, P. J. Hotez, and B. Beutler. 1985. Weight loss associated with an endotoxin-induced mediator from peritoneal macrophages: the role of cachectin (tumor necrosis factor). Immunol. Lett. 229: 869.
13. Dayer, J.-M., J. Breard, L. Chess, and S. M. Krane. 1979. Participation of monocytemacrophages and lymphocytes in the production of a factor that stimulates collagenase and prostaglandin release by rheumatoid synovial cells. J. Clin. Invest. 64: 1386.
14. Mizel, S. B., J.-M. Dayer, S. M. Krane, and S. E. Mergenhagen. 1981. Stimulation of rheumatoid synovial cell collagenase and prostaglandin production by partially purified lymphocyte-activating factor (interleukin 1). Proc. Natl. Acad. Sci. USA. 78: 2474.
15. Dayer, J.-M., C. Zavadil-Grob, C. Ucla, and B. Mach. 1984. Induction of human interleukin 1 mRNA measured by collagenase and prostaglandin E2-stimulating activity in rheumatoid synovial cells. Eur. J. Immunol. 14: 898.
16. Krane, S. M., S. R. Goldring, andJ.-M. Dayer. 1982. Interactions among lymphocytes, monocytes, and other synovial cells in the rheumatoid synovium. In Lymphokines, vol. 7. E. Pick, editor. Academic Press, New York.
17. Baracos, V., H. P. Rodemann, C. A. Dinarello, and A. L. Goldberg. 1983. Stimulation of muscle protein degradation and prostaglandin-E2 release by leukocytic pyrogen (interleukin-I). A mechanism for the increased degradation of muscle proteins during fever. N. Engl. J. Med. 308: 553.
18. Rodemann, H. P., and A. L. Goldberg. 1982. Arachidonic acid, prostaglandin E2 and F2 alpha influence rates of protein turnover in skeletal and cardiac muscle. J. Biol. Chem. 257: 1632.
19. Robinson, D. R., A. H. Tashjian, and L. Levine. 1975. Prostaglandin-stimulated bone resorption by rheumatoid synovia. A possible mechanism for bone destruction in rheumatoid arthritis. J. Clin. Invest. 56: 1181.
20. Dayer, J.-M., M. L. Stephenson, E. Schmidt, W. Karge, and S. M. Krane. 1981. Purification of a factor from human blood monocyte-macrophages which stimulates the production of collagenase and prostaglandin E2 by cells cultured from rheumatoid synovial tissues. FEBS (Fed. Eur. Biochem. Soc.) Lett. 124: 253.
21. Beutler, B., I. W. Milsark, and A. Cerami. 1985. Cachectin/tumor necrosis factor:production, distribution, and metabolic fate in vivo. J. Immunol. In press.
22. Abe, S., T. Gatanaga, M. Yamazaki, G. Soma, and D. Mizuno. 1985. Purification of rabbit tumor necrosis factor. FEBS (Fed. Eur. Biochem. Soc.) Lett. 180: 203.
23. 2 and collagenase stimulating factors. Biochem. Biophys. Acta. In press.
24. Dinarello, C. A. 1984. Interleukin-1. Rev. Infect. Dis. 6: 51.
25. Kawakami, M., Y. Ikeda, N. Le Trang, W. Vine, and A. Cerami. 1984. Studies of conditions and agents that stimulate and inhibit the production of cachectin by macrophages. Proc. lnternat. Union Pharmacol. 377.
26. Lomedico, P. T., U. Gubler, C. P. Hellmann, M. Dukovich, J. G. Giri, Y.-C. E. Pan, K. Collier, R. Semionow, A. O. Chua, and S. B. Mizel. 1984. Cloning and expression of murine interleukin-1 cDNA in Escherichia coli. Nature (Lond.). 312: 458.