Immunobiological Significance of the Ro/SSA Antigen-Antibody System

Archives of Dermatology

Volumn 121, Issue 3, 1985, Pages 327-330

  Sontheimer, Richard D ^a  

^a NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIAGNOSIS; EDITORIAL; ETIOLOGY; HUMAN; PRIORITY JOURNAL; RO(SSA) ANTIBODY; SJOEGREN SYNDROME; SYSTEMIC LUPUS ERYTHEMATOSUS;

ANTIGEN-ANTIBODY COMPLEX; ANTIGENS; HUMAN; SUPPORT, U.S. GOV'T, P.H.S.; TRANSCRIPTION FACTORS;

EID: 0021969895     PISSN: 0003987X     EISSN: 15383652     Source Type: Journal    
DOI: 10.1001/archderm.1985.01660030049015     Document Type: Article

References (38)

1. Alspaugh MA, Tan EM: Antibodies to cellular antigens in Sjögren's syndrome. J Clin Invest 1975;55:1067–1073.
2. Franco HL, Weston WL, Peebles C, et al: Autoantibodies directed against sicca syndrome antigens in the neonatal lupus syndrome. J Am Acad Dermatol 1981;4:67–72.
3. Kephart DC, Hood AF, Provost TT: Neonatal lupus erythematosus: New serologic findings. J Invest Dermatol 1981;77:331–333.
4. Miyagawa S, Kitamura W, Yoshioka J, et al: Placental transfer of the anticytoplasmic antibodies in annular erythema of newborns. Arch Dermatol 1981;117:569–572.
5. Provost TT, Ahmed AR, Maddison PJ, et al: Antibodies to cytoplasmic antigens in lupus erythematosus: Serologic markers for systemic disease. Arthritis Rheum 1977;20:1457–1463.
6. Maddison PJ, Provost TT, Reichlin M: Serological findings in patients with ‘ANA-negative’ systemic lupus erythematosus. Medicine 1981;60:87–94.
7. Sontheimer RD, Maddison PJ, Reichlin M, et al: Serologic and HLA associations in subacute cutaneous lupus erythematosus, a clinical subset of lupus erythematosus. Ann Intern Med 1982;97:664–671.
8. Vandersteen PR, Provost TT, Jordon RE, et al: C2 deficient systemic lupus erythematosus. Arch Dermatol 1982;118:584–587.
9. Provost TT, Arnett FC, Reichlin M: Homozygous C2 deficiency, lupus erythematosus, and anti-Ro(SS-A) antibodies. Arthritis Rheum 1983;26:1279–1281.
10. Wermuth DJ, Geoghegan WD, Jordon RE: Anti-Ro/SSA antibodies: Association with a particulate (large speckledlike thread) immunofluorescent nuclear staining pattern. Arch Dermatol 1985;121:335–338.
11. Clark G, Reichlin M, Thomas TB Jr: Characterization of a soluble cytoplasmic antigen reactive with sera from patients with systemic lupus erythematosus. J Immunol 1969;102:117–122.
12. Alspaugh M, Maddison PJ: Resolution of identity of certain antigen-antibody systems in systemic lupus erythematosus and Sjögren's syndrome. Arthritis Rheum 1979;22:796–798.
13. Lerner MR, Boyle JA, Hardin JA, et al: Two novel classes of small ribonucleo proteins detected by antibodies associated with lupus erythematosus. Science 1981;211:400–402.
14. Venables PJ, Smith PR, Maini RN: Purification and characterization of the Sjögren's syndrome A and B antigens. Clin Exp Immunol 1983;54:731–738.
15. Wolin SL, Steitz JA: The Ro small cytoplasmic proteins: Identification of the antigenic protein and its binding site on the Ro RNAs. Proc Natl Acad Sci USA 1984;81:1996–2000.
16. Lieu TS, Jaing M, Steigerwald JC, et al: Identification of the SS-A/Ro intracellular antigen with autoimmune sera. J Immunol Methods 1984;71:217–228.
17. Elkon KB, Culhane L: Partial immunochemical characterization of the Ro and La proteins using antibodies from patients with the sicca syndrome and lupus erythematosus. J Immunol 1984;132:2350–2356.
18. Deng JS, Sontheimer RD, Gilliam JN: Molecular characteristics of SS-B/La and SS-A/Ro cellular antigens. J Invest Dermatol, in press.
19. Hendrick JP, Wolin SL, Rinke J, et al: Ro small cytoplasmic ribonucleoproteins are a subclass of La ribonucleoproteins: Further characterization of the Ro and La small ribonucleoproteins from uninfected mammalian cells. Mol Cell Biol 1981;1:1138–1149.
20. Kato N, Hoshino H, Harada F: Nucleotide sequence of 4.55 RNA (C8 or hY5) from HeLa cells. Biochem Biophys Res Commun 1982;108:363–370.
21. Wolin SL, Steitz JA: Genes for two small cytoplasmic Ro RNAs are adjacent and appear to be single-copy in the human genome. Cell 1983;32:735–744.
22. Harmon CE, Deng JS, Peebles CL, et al: The importance of tissue substrate in the SS-A/Ro antigen-antibody system. Arthritis Rheum 1984;27:166–173.
23. Alspaugh MA, Talal N, Tan EM: Differentiation and characterization of autoantibodies and their antigens in Sjögren's syndrome. Arthritis Rheum 1976;19:216–222.
24. Dore N, Synkowski D, Provost TT: Antinuclear antibody determinations in Ro(SS-A)-positive, antinuclear antibody-negative lupus and Sjögren's syndrome patients. J Am Acad Dermatol 1983;8:611–615.
25. Burnham TK, Bank PW: Antinuclear antibodies: I. Patterns of nuclear immunofluorescence. J Invest Dermatol 1974;62:526–534.
26. Chang JY, Deng JS, Sontheimer RD, et al: Development and characterization of a monoclonal anti-SS-A/Ro antibody, abstracted. J Invest Dermatol 1984;82:390.
27. Norris DA, Ryan SR, Fritz KA, et al: The role of RNP, Sm, and SSA-specific antisera from patients with lupus erythematosus in inducing antibody dependent cellular cytotoxicity of ribonucleoprotein-coated targets, abstracted. Clin Res 1982;30:264A.
28. LeFeber WP, Norris DA, Huff JC, et al: Induction of nuclear antigen expression in human keratinocytes by ultraviolet light, abstracted. J Invest Dermatol 1983;80:328.
29. Lee N, Norris D, Surbrugg S, et al: An animal model for antibody deposition in cutaneous lupus, abstracted. J Invest Dermatol 1984;82:427.
30. Lee LA, Harmon CE, Huff JC, et al: SSA(Ro) antigen expression in human fetal, neonatal and adult tissues, abstracted. Arthritis Rheum 1984;27:S20.
31. Harmon CE, Lee LA, Huff JC, et al: The frequency of antibodies to the SS-A/Ro antigen in pregnancy sera, abstracted. Arthritis Rheum 1984;27:S20.
32. Callen JP, Fowler JF, Kulick JB, et al: Neonatal lupus erythematosus: Discordant disease expression in fraternal twins: Serologic and immunogenetic studies, abstracted. Arthritis Rheum 1984;27:S62.
33. Alarcón-Segovia D, Ruiz-Arguelles A, Fishbein E: Antibody to nuclear ribonucleoprotein penetrates live human mononuclear cells through Fc-receptors. Nature 1978;271:67–69.
34. Alarcón-Segovia D, Ruiz-Arguelles A, Llorente L: Antibody penetration into living cells: II. Antiribonucleoprotein IgG penetrates into Tγ lymphocytes causing their deletion and their abrogation of suppressor function. J Immunol 1979;122:1855–1862.
35. Bell DA, Maddison PJ: An examination of autoantibodies in relationship to clinical features of disease and HLA antigens. Arthritis Rheum 1980;23:1268–1273.
36. Marsh DG, Meyers DA, Freidhoff LR, et al: Association of HLA phenotypes Al, B8, DW3 and A3, B7, BW2 with allergy, abstracted. Fed Proc 1980;39:936.
37. Lawley TJ, Hall RP, Fauci AS, et al: Defective Fc receptor functions associated with the HLA-B8/DR3 haplotype. N Engl J Med 1980;304:185–192.
38. Ambinder JM, Chiazzi N, Gibofsky A, et al: Special characteristics of cellular immune function in normal individuals of the HLA DR3 type. Clin Immunol Immunopathol 1984;23:269–274.