Exposure to anesthetic gases and reproductive outcome: A review of the epidemiologic literature

Journal of Occupational Medicine

Volumn 27, Issue 9, 1985, Pages 659-668

  Tannenbaum, Terry N ^a   Goldberg, Robert J ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANESTHETIC GAS;

ANESTHESIST; CONGENITAL DISORDER; CONGENITAL MALFORMATION; EMBRYO; EPIDEMIOLOGY; ETIOLOGY; FEMALE GENITAL SYSTEM; HOSPITAL PERSONNEL; HUMAN; INTOXICATION; MALE GENITAL SYSTEM; NURSE; OCCUPATIONAL EXPOSURE; PREGNANCY; PRIORITY JOURNAL; REPRODUCTION; RISK FACTOR; SPONTANEOUS ABORTION; SURVEY;

ABNORMALITIES, DRUG-INDUCED; ABORTION, SPONTANEOUS; ANESTHESIOLOGY; ANESTHETICS; DATA COLLECTION; EPIDEMIOLOGIC METHODS; FEMALE; GREAT BRITAIN; HUMAN; MALE; OCCUPATIONAL DISEASES; PREGNANCY; REPRODUCTION; RISK; UNITED STATES;

EID: 0021965266     PISSN: 00961736     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (77)

1. Jastak JT, Sternfield W: Trace concentrations of anesthetic gases: A brief review. J Am Dent Assoc 95: 758-762, 1977.
2. Ferslandig LL: Trace concentrations of anaesthetic gases: A critical review of their disease potential. Anesth Analg 57: 328-345, 1978.
3. Smith WDA: Pollution and the anesthetist. Int Anesth Clin 16: 131-173, 1978.
4. Spence AA, Knill-Jones RP: Is there a health hazard in anaesthetic practice? Br J Anaesth 50: 213-219, 1978.
5. Vessey MP: Epidemiological studies of occupational hazards of anesthesia-a review. Anesthesia 33: 430-438, 1978.
6. Baden JM, Simmon VF: Mutagenic effects of inhalational anesthetics. Mutat Res 75: 169-189, 1980.
7. Vessey MP, Nunn JF: Occupational hazards of anesthesia. Br Med J 281: 696-698, 1980.
8. Ferstandig LL: Trace concentrations of anesthetic gases. Acta Anesth Scand Suppl 25: 38-43, 1982.
9. Vaisman AI: Working conditions in surgery and their effect on the health of anesthesiologists. Eksp Khir Anesth 3: 44-49, 1967.
10. Askrog V, Harvald B: Teratogen effekt of inhalation anaestetika. Saertvk Nord Med 3: 490-500, 1970.
11. Cohen FN, Belville JW, Brown BW: Anesthesia, pregnancy, and miscarriage: A study of operating room nurses and anesthetists. Anes-thesiology 34: 343-347, 1971.
12. Knill-Jones RP, Moir DB, Rodriguez LV: Anesthetic practice and pregnancy: Controlled survey of women anesthetists in the United Kingdom. Lancet 1: 1326-1328, 1972.
13. Knill-Jones RP, Newman BJ, Spence AA: Anaesthetic practice and pregnancy: Controlled survey of male anaesthetists in the United Kingdom. Lancet 2: 807-809, 1975.
14. Rosenberg P, Kirves A: Miscarriage among operating theatre staff. Acta Anaesth Scand Suppl 53: 37-42, 1973.
15. Corbett TH, Cornell RG, Endres JL: Birth defects among children of nurse-anesthetists. Anesthesiology 41: 341-344, 1974.
16. American Society of Anesthesiologists: Occupational disease among operating room personnel: A national study. Anesthesiology 41: 321-340, 1974.
17. Cohen EN, Brown BW Jr, Bruce DL, et al: A survey of anesthetic health hazards among dentists. J Am Dent Assoc 90: 1291-1296, 1975.
18. Cohen EN, Brown BW, Wu ML, et al: Occupational disease in dentistry and chronic exposure to trace anesthetic gases. J Am Dent Assoc 101: 21-31, 1980.
19. Pharoah POD, Alberman E, Doyle P: Outcome of pregnancy among women in anaesthetic practice. Lancet 1: 34-36, 1977.
20. Rosenberg PH, VanHinen H: Occupational hazards to reproduction and health in anaesthetists and paediatricians. Acta Anaesth Scand 22: 202-207, 1978.
21. Ericson A, Källen B: Survey of infants born in 1973 or 1975 to Swedish women working in operating rooms during their pregnancies. Anesth Analg 58: 302-305, 1979.
22. Lauwerys R, Siddons H, Misson CB, et al: Anaesthetic health hazards among Belgian nurses and physicians. Int Arch Occup Environ Health 48: 195-203, 1981.
23. Tomlin PJ: Health problems of anaesthetists and their families in the West Midlands. Br Med J 1: 779-784, 1979.
24. Axelsson G, Rylander R: Exposure to anaesthetic gases and spontaneous abortion: Response bias in a postal questionnaire study. Int J Epidemiol 11: 250-256, 1982.
25. Criqui MH, Barrell-Connor E, Austin M: Differences between respondents and non-respondents in a population-based cardiovascular disease study. Am J Epidemiol 108: 367-372, 1978.
26. Criqui MH: Response bias and risk ratios in epidemiologic studies. Am J Epidemiol 109: 394-399, 1979.
27. Heilbrun LK, Nomura A, Stemmerman GN: The effects of nonresponse in a prospective study of cancer. Am J Epidemiol 116: 353-363, 1982.
28. Anderson NB: The effect of CNS depressants on mitosis. Acta Anaesth Scand 10: 2-36, 1966.
29. Fink BR: Effect of anesthesia on cell division, in Gray TC, New JF (Eds.): General Anesthesia Vol. 1. London: Butterworths, 1971, pp 42-54.
30. Sturrock JE, New JF: Mitosis in mammalian cells during exposure to anesthetics. Anesthesiology 43: 21-33, 1975.
31. Kusyk CJ, Hso TC: Mitotic anomalies induced by three inhalation halogenated anesthetics. Environ Res 12: 366-370, 1976.
32. Grant CJ, Powell JN, Radford SG: Halothane and the cell cycle. Br J Anaesth 45: 923, 1973.
33. Grant CJ, Powell JN, Radford SG: Effects of halothane on DNA synthesis and mitosis in root tip meristems of Vicia faba. Br J Anaesth 46: 653-657, 1974.
34. Grant CJ, Powell JN: Chromosomal abnormalities induced in Vicia faba by inhalational anesthetics. Heredity 38: 270, 1977.
35. Grant CJ, Powell JN, Radford SG: Induction of chromosomal abnormalities by inhalational anesthetics. Mut Res 46: 177-184, 1977.
36. Coate WB, Kapp RW, Lewis TR: Chronic exposure to low concentrations of halothane-nitrous oxide: Reproductive and cytogenetic effects in the rat. Anesthesiology 50: 310-318, 1979.
37. Carney FMT, Van Dyke RA: Halothane hepatitis-a critical review. Anesth Analg 51: 135-160, 1972.
38. Chang LW, Katz J: Pathologic effects of chronic halothane inhalation: An overview. Anesthesiology 45: 640-653, 1976.
39. Mazze RI, Shue GL, Jackson SH: Renal dysfunction associated with methoxyflurane anesthesia. JAMA 216: 278-288, 1971.
40. Lassen HCA, Henriksen E, Nenkirch F, et al: Treatment of tetanus: severe bone marrow depression after prolonged nitrous oxide anesthesia. Lancet 1: 527-530, 1956.
41. Ablett JL: Tetanus and the anesthetist. Br J Anesth 28: 258-273, 1956.
42. Wilson P, Martin FIR, Last PM: Bone marrow depression in tetanus: Report of a fatal case. Lancet 2: 442-443, 1956.
43. Amess JAL, Burman JF, Greany M, et al: The effect of nitrous oxide on hematopoiesis, in Proc Int Soc Haematol. Istanbul: 1977, p 614.
44. Amess JAL, Burman JF, Rees GM, et al: Megaloblastic haema-topaeisis in patients receiving nitrous oxide. Lancet 2: 339-342, 1978.
45. Skacel P, Chanamin I, Lumb M, et al: Serial Studies on the Effects of Nitrous Oxide (NO2) in Man. Sheffield, England: British Society of Haematologists, March, 1981.
46. Sahenk Z, Herdel JR, Coum D, et al: Polyneuropathy from inhalation of NO2 cartridges through a whipped cream dispenser. Neurology 28: 485-487, 1978.
47. Layzer RB, Fishman RA, Schafer JA: Neuropathy following abuse of nitrous oxide. Neurology 28: 504-506, 1978.
48. Layzer RB: Myelonephropathy after prolonged exposure to nitrous oxide. Lancet 2: 1227-1230, 1978.
49. Deacon R, Perry J, Lumb M, et al: Selective inactivation of vitamin B12 in rats by nitrous oxide. Lancet 2: 1023-1024, 1978.
50. Nunn JF, Chanarin I: Nitrous oxide and vitamin B12. Br J Anaesth 50: 1089-1090, 1978.
51. Deacon R, Lumb M, Chanarin I, et al: Inactivation of methionine synthase by nitrous oxide. Eur J Biochem 104: 419-423, 1980.
52. Nunn JF: Anesthesia and the leukocyte. Acta Anaesth Belg 30 (suppl): 23-28, 1979.
53. Chanarin I: The effects of nitrous oxide on cobalamines, folates and on related events. CRC Crit Rev Toxicol 10: 129-213, 1982.
54. Chenaweth MD, Leong BKJ, Sparschu GL, et al: Toxicides of methoxyflurane, halothane and diethyl ether in laboratory animals on repeated inhalation at subanesthetic concentrations, in Fuik BR (Ed.): Cellular Biology and Toxicity of Anesthetics. Baltimore: Williams & Wilkins Co., 1972, pp 275-285.
55. Stevens WC, Halsey MJ, Munger W, et al: Comparative toxicides of halothane, isoflurane, and diethyl ether at subanesthetic concentrations In laboratory animals. Anesthesiology 42: 408-419, 1975.
56. Stevens WC, Eger EI II, White A, et al: Comparative toxicities of enflurane, fluroxene, and nitrous oxide at subanesthetic concentrations in laboratory animals. Can Anaesth Soc J 24: 479-490, 1977.
57. Green CJ: Anaesthetic gases and health risks to laboratory personnel: A review. Lab Animals 15: 397-403, 1981.
58. Halsey MJ: Studying toxicity of inhaled general anesthesthetics. Br J Anaesth 53: 57S-62S, 1981.
59. Basford AB, Fink RB: The teratogenicity of halothane in the rat. Anesthesiology 29: 1167-1173, 1968.
60. Bussard DA, Stoling LK, Peterson IM: Fetal changes in hamsters anesthetized with nitrous oxide. Anesthesiology 41: 275-278, 1974.
61. Wharton RS, Sieverpiper TS, Mazze RI: Developmental toxicity of methoxyflurane in mice. Anesth Analg 59: 421-425, 1980.
62. Lane GA, Nahrwold ML, Tait AR, et al: Anesthetics as teratogens: Nitrous oxide is fetotoxic, xenon is not. Science 210: 899-901, 1980.
63. Viera E, Cleaton-Jones P, Austin JC, et al: Effects of low concentrations of nitrous oxide on rat fetuses. Anesth Analg 59: 175-177, 1980.
64. Wharton RS, Mazze RI, Baden JM, et al: Fertility, reproduction and postnatal survival In mice chronically exposed to halothane. Anes-thesiology 48: 167-174, 1978.
65. Viera E, Cleaton-Jones PE, Austin JL, et al: Intermittant exposure of ground rats to 1% nitrous oxide and the effect on the postnatal growth of their offspring. S Afr Med J 53: 106-108, 1978.
66. Corbett TH, Cauell RG, Endres JL, et al: Effects of low concentrations of nitrous oxide on rat pregnancy. Anesthesiology 39: 299-301, 1973.
67. Pope WDB, Halsey MJ, Lansdown ABG, et al: Fetotoxicity in rats following chronic exposure to halothane, nitrous oxide or methoxyflurane. Anesthesiology 48: 11-16, 1978.
68. Pope WDB, Persaud TVN: Faetal growth retardation in the rat following chronic exposure to the inhalation anaesthetic enflurane. Experientla 34: 1332-1333, 1977.
69. Wharton RS, Mazze RI, Wilson AI: Reproduction and fetal development in mice chronically exposed to enflurane. Anesthesiology 54: 505-510, 1981.
70. Viera E: Effect of the chronic administration of nitrous oxide, 0.5%, to ground rats. Br J Anaesth 51: 283-287, 1979.
71. Mazze RI, Wilson AI, Rice SA, et al: Reproduction and fetal development in mice chronically exposed to nitrous oxide. Teratology 26: 11-16, 1982.
72. Strout CD, Nahrwold ML, Taylor MD, et al: Effects of suba-nesthetic concentrations of enflurane on rat pregnancy and early development. Environ Health Perspect 21: 211-214, 1977.
73. Green CJ, Monk SJ, Knight JF, et al: Chronic exposure of rats to enflurane 200 ppm: No evidence of toxicity or teratogenicity. Br J Anaesth 54: 1097-1104, 1982.
74. Halsey MJ, Green CJ, Monk SJ, et al: Maternal and paternal chronic exposure to enflurane and halothane: Fetal and histological changes in the rat. Br J Anaesth 53: 203-215, 1981.
75. Kennedy GL, Smith SH, Keplinger ML, et al: Reproductive and teratologic studies with halothane. Toxicol Appl Pharmacol 35: 467-474, 1976.
76. Lansdown ABG, Pope PBG, Halsey MJ, et al: Analyses of fetal development in rats following maternal exposure to subanesthetic concentrations of halothane. Teratology 13: 299-304, 1976.
77. Cohen EN: Waste anesthetic gases and reproductive health in operating room personnel, in Proceedings of a Workshop on Methodology for Assessing Reproductive Hazards in the Workplace. U.S. Dept. of Health and Human Services, Public Health Service, Center for Disease Control, National Institute for Occupational Safety and Health, 1978.