Circadian changes in anticoagulant effect of heparin infused at a constant rate

British Medical Journal (Clinical research ed.)

Volumn 290, Issue 6465, 1985, Pages 341-344

  Levi, F A ^c   Reinberg, A ^c   De Bonadona, J F ^a   Queneau, P M ^a  

^a SERVICE DE NEUROLOGIE   (France)

^b Hopital Bellevue   (France)

^c FONDATION OPHTALMOLOGIQUE ADOLPHE DE ROTHSCHILD   (France)

Author keywords

[No Author keywords available]

Indexed keywords

HEPARIN;

ARTICLE; BLOOD AND HEMOPOIETIC SYSTEM; BLOOD CLOTTING TEST; CARDIOVASCULAR SYSTEM; CIRCADIAN RHYTHM; CLINICAL ARTICLE; DRUG DOSE; DRUG EFFICACY; DRUG THERAPY; HUMAN; INFUSION PUMP; INTRAVENOUS DRUG ADMINISTRATION; PERIPHERAL VASCULAR SYSTEM; PRIORITY JOURNAL; THERAPY; THROMBOEMBOLISM; VENOUS THROMBOEMBOLISM;

AGED; ANTICOAGULANTS; BLOOD COAGULATION TESTS; CIRCADIAN RHYTHM; FEMALE; HEPARIN; HUMANS; INFUSIONS, PARENTERAL; MALE; MIDDLE AGED; PARTIAL THROMBOPLASTIN TIME; PULMONARY EMBOLISM; THROMBOPHLEBITIS;

EID: 0021943976     PISSN: 02670623     EISSN: None     Source Type: Journal    
DOI: 10.1136/bmj.290.6465.341     Document Type: Article

References (15)

1. Barrit DW, Jordan SC. Anticoagulant drugs in the treatment of pulmonary embolism: A controlled trial. Lancet 1960;1:1309-1312.
2. Bauer G. Heparin as a therapeutic against thrombosis. Acta Chir Scand 1942:86:267-272.
3. Mant MJ, O’Brien B, Thong et al KL Haemorrhagic complications of heparin therapy. Lancet 1977;1: 1133-1135.
4. Wilson JE, Bynum LJ, Parkey RW. Heparin therapy in venous thrombo embolism. Am J Med 1981;70:808-816.
5. Hattersley PG, Mitsuoka JC, King JH. Heparin therapy for thromboembolic disorders. JAMA 1983;250:1413-1416.
6. Reinberg A, Smolensky MH, Levi F. Clinical chronopharmacology. Biomedicine 1981;34:171-178.
7. Basu D, Gallus A, Hirsh et al J A prospective study of the value of monitoring heparin treatment with the activated partial thromboplastin time. N Engl J Med 1972;287:324-327.
8. Raby C. Héparinothérapie contrôlée. Presse Medicale 1967;75:1526.
9. Yin ET, Wessler S, Butler J. Plasma heparin: A unique practical, submicrogramsensitive assay. J Lab Clin Med 1973;81:298-310.
10. Nelson W, Tong Y, Lee JK, Halberg F. Methods for cosinor rhythmometry. Chronobiologia 1979;6:305-23.
11. Brandt JT, Triplett DA. Laboratory monitoring of heparin. Effect of reagents and instruments on the activated partial thromboplastin time. Am J Clin Pathol 1981;76:530-7.
12. Wessler S, Gitel SN. Heparin: New concepts relevant to clinical use. Blood 1979;53:525-44.
13. Kakkar W, Djazaeri B, Fok et al J Low-molecular-weight heparin and prevention of postoperative deep vein thrombosis. Br Med J 1982;284:375-9.
14. Reinberg A, Smolensky MH. Circadian changes of drug disposition in man. Clin Pharmacokinet 1982;7:401-20.
15. Petralito A, Mangiafico RA, Gibhno et al S Daily modifications of plasma fibrinogen, platelets aggregation, Howell's time, PTT, TT, and antithrombin III in normal subjects and in patients with vascular disease. Chronobiologia 1982;9:195-201.