Toxic properties of arachidonic acid on normal, ischemic and reperfused hearts. Indirect evidence for free radical involvement

Prostaglandins, Leukotrienes and Medicine

Volumn 17, Issue 2, 1985, Pages 251-264

  Karmazyn, M ^a   Moffat, M P ^a  

^a DALHOUSIE UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; ARACHIDONIC ACID; CREATINE KINASE; INDOMETACIN; NIFEDIPINE; NORDIHYDROGUAIARETIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; DRUG EFFICACY; DRUG TOXICITY; HEART; INTOXICATION; ISCHEMIA; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMAL; ARACHIDONIC ACID; ARACHIDONIC ACIDS; BLOOD PRESSURE; CORONARY DISEASE; CREATINE KINASE; FREE RADICALS; HEART; INDOMETHACIN; MALE; MYOCARDIAL CONTRACTION; PERFUSION; RATS; RATS, INBRED STRAINS; SUPPORT, NON-U.S. GOV'T;

EID: 0021925467     PISSN: 02621746     EISSN: None     Source Type: Journal    
DOI: 10.1016/0262-1746(85)90112-X     Document Type: Article

References (22)

1. Cardiac and renal lipases and prostaglandin biosynthesis
2. Production of lysophospholipids by a sarcolemmal fraction from canine myocardium
3. 2
4. Prostacyclin is the major prostaglandin released from the isolated perfused rabbit and rat heart
5. How is the level of free arachidonic acid controlled in mammalian cells?
6. Coronary vasoconstrictor and vasodilator actions of arachidonic acid in the isolated perfused heart of the rat
7. Alterations in membrane integrity and cellular constituents by arachidonic acid in neuroblastoma and glioma cells
8. A direct protective influence of sulphinpyrazone on ischemic/reperfused rat hearts
9. A possible mechanism of inotropic action of prolactin on rat heart
10. Effect of Prostaglandins on rat heart sarcolemmal ATPases
11. Comparative effects of calcium channel blocking agents and role of varying extracellular calcium concentration on hypoxia/reoxygenation and ischemia/reperfusion cardiac injury
12. Putative role of hydroperoxy acids and leukotrienes in vascular diseases: mechanism of indomethacininduced acute renal failure — a hypothesis
13. Oxidation of arachidonic acid in micelles by superoxide and hydrogen peroxide
14. Vitamin E and lipid antioxidants in free radical initiated reactions
15. Inhibition of the slow inward current by nifedipine in mammalian ventricular myocardium
16. Prostaglandin actions and interactions on isolated perfused rat hearts
17. +)-stimulated ATPase of heart by fatty acids
18. Lipid-membrane interactions and the pathogenesis of ischemic damage in the myocardium
19. The mechanism of α-adrenergic activation of the dog coronary artery
20. Prostaglandins and polyunsaturated fatty acids in heart muscle
21. The biosynthesis and metabolism of pcostaglandins
22. The role of lipid peroxidation in pathogenesis of ischemic damage and the antioxidant protection of the heart