Effect of oxidants and antioxidants on chromosomal breakage in Fanconi anemia lymphocytes

Human Genetics

Volumn 69, Issue 1, 1985, Pages 62-65

  Dallapiccola, B ^a   Porfirio, B ^b   Mokini, V ^b   Alimena, G ^b   Isacchi, G ^b   Gandini, E ^b  

^a UNIVERSITY OF URBINO   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BUTADIENE DIEPOXIDE; BUTYL HYDROPEROXIDE; HYDROGEN PEROXIDE;

BLOOD AND HEMOPOIETIC SYSTEM; CHROMOSOME BREAKAGE; CONGENITAL DISORDER; FANCONI ANEMIA; HEREDITY; HISTOLOGY; HUMAN; LYMPHOCYTE CULTURE; MAJOR CLINICAL STUDY; PRIORITY JOURNAL;

ANEMIA, APLASTIC; ANTIOXIDANTS; ASCORBIC ACID; CELLS, CULTURED; CHROMOSOME ABERRATIONS; CROSS-LINKING REAGENTS; CYSTEINE; EPOXY COMPOUNDS; ETHERS, CYCLIC; FANCONI ANEMIA; GLUTATHIONE; HETEROZYGOTE; HOMOZYGOTE; HUMANS; HYDROGEN PEROXIDE; LYMPHOCYTES; MERCAPTOETHANOL; PEROXIDES; THIOPRONINE;

EID: 0021923545     PISSN: 03406717     EISSN: 14321203     Source Type: Journal    
DOI: 10.1007/BF00295530     Document Type: Article

References (28)

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2. An enzyme catalysing the conjugation of epoxides with glutathione
3. Erythrocyte superoxide dismutase in ataxia telangiectasia and Fanconi's anemia
4. Cytogenetic differentiation of Fanconi anemia, “idiopathic” aplastic anemia, and Fanconi anemia heterozygotes
5. Absence of chromosome heterogeneity between classical Fanconi's anemia and the Estren-Dameshek type
6. Detection of Fanconi's anemia heterozygotes by different cytogenetic approaches
7. Increased glutathione S-transferase and fast decay of reduced glutathione in Fanconi's anemia
8. Clinical and cytogenetic diversity in Fanconi's anemia
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10. Spectrum of anomalies in Fanconi's anemia
11. Deficiency of DNA ligase activity in Fanconi's anemia
12. An international system for human cytogenetic nomenclature
13. Effect of oxygen tension on chromosomal aberrations in Fanconi anemia
14. Erythrocyte superoxide dismutase deficiency in Fanconi anaemia established by two independent methods of assay
15. Oxygen-dependence of chromosomal aberrations in Fanconi's anemia
16. The use of short-term tests to measure the preventive action of reducing agents on formation and activation of carcinogenic nitroso compounds
17. Selective modification of glutathione metabolism
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19. Lack of effect of vitamin C on the incidence of chromosome anomalics induced by influenza virus in germ cells of mice
20. Defective DNA repair in Fanconi's anemia
21. Defective repair of ultraviolet and gamma ray-damaged DNA in Fanconi's anemia
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23. Deficiency of gamma-ray excision repair in skin fibroblasts from patients with Fanconi's anemia
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28. Mutagenic action of ascorbic acid