Focal cerebral ischemia: reduction in size of infarcts by ventriculo-subarachnoid perfusion with fluorocarbon emulsion

Brain Research

Volumn 328, Issue 2, 1985, Pages 223-231

  Bose, Bikash ^a   Osterholm, Jewell L ^a   Triolo, Anthony ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

cat; fluorocarbon; focal cerebral ischemia; tetrazolium staining; ventriculo cisternal perfusion

Indexed keywords

FLUOROCARBON; PERFLUOROBUTYLTETRAHYDROFURAN;

ANIMAL EXPERIMENT; BLOOD SUBSTITUTION; BRAIN ISCHEMIA; CAT; CELL PROTECTION; CENTRAL NERVOUS SYSTEM; DRUG EFFICACY; INFARCTION; NONHUMAN; PERIPHERAL VASCULAR SYSTEM; PRIORITY JOURNAL; STROKE;

ANIMAL; BRAIN ISCHEMIA; CATS; CEREBRAL VENTRICLES; EMULSIONS; FLUOROCARBONS; OXYGEN; PERFUSION; SUBARACHNOID SPACE;

EID: 0021916143     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-8993(85)91033-9     Document Type: Article

References (44)

1. Cerebral ischemia II The no-reflow phenomenon
2. An isolated perfusion rat brain preparation, its spontaneous and stimulated activity
3. A reproducible experimental model of focal cerebral ischemia in the cat
4. Cerebral ischemia: III. Vascular changes
5. Can fluorocarbon emulsions be used as artificial blood?
6. Survival of mammals breathing organic liquids equilibrated with oxygen at atmospheric pressure
7. Ring versus straight chain perfluorocarbon emulsions for perfusion media
8. Perfusion of the cervical spinal cord in situ of adult rats using a perfluorocarbon emulsion
9. Fluorocarbon perfusion medicum applied to the isolated rat brain
10. 2 induced by anoxic anoxia
11. The permeability of brain cells and capillaries to various water-soluble molecules as determined by ventriculocisternal perfusion
12. Impaired perfusion following cerebrovascular stasis: a review
13. Increased free fatty acid turnover in CSF during hypothesion in dogs
14. ‘Bloodless’ rats through the use of artificial blood substitute
15. Potential uses of artificial blood substitutes
16. Survival of rats having red cells totally replaced with emulsified fluorocarbon
17. Survival of rats perfused with a fluorocarbon-detergent preparation
18. Perfluorocarbon emulsion in the perfusion of canine organs
19. Acute ischemic cerebral infarction treated by perfluorochemicals
20. Can perfluorochemicals reduce cerebral ischemia?
21. Oxygenated fluorocarbon perfusion as treatment of acute spinal cord compression injury in dogs
22. Bulk flow and diffusion in the cerebrospinal fluid system of the goat
23. Reversibility of ischemic brain damage
24. Cation activities in reversible ischemia of the cat brain
25. Resuscitation of the monkey brain after 1 hour complete ischemia: I. Physiological and morphological observations
26. Purine nucleotide metabolism in the cat brain after one hour of complete ischemia
27. Cerebral ATP and lactate levels in the squirrel monkey following occlusion of the middle cerebral artery
28. Neural activities during replacement of blood with fluorocarbon emulsion
29. Efficacy of fluorocarbon (Fluosol-DA) on brain in low hematocrit condition: Part 1. Study on severely hemodiluted dogs by exchange transfusion
30. Adenosine in rate cerebral cortex: its determination, normal values, and correlation to AMP and cyclic AMP during short lasting ischemia
31. Severe cerebral ischemia treatment by ventriculo-subarachnoid perfusion with an oxygenated fluorocarbon emulsion
32. Perfusion of the cerebral ventricular system in unanesthetized goats
33. Protective effect of Fluosol-DA in acute cerebral ischemia
34. Extracellular space of brain as determined by diffusion of inulin from the ventricular system
35. Fluorocarbon emulsions and cerebral microcirculation
36. Brain mitochondrial function after ischemia and hypoxia: II. Normotensive systemic hypoxemia
37. Metabolic aspects of cerebral hypoxia-ischemia
38. Recirculatory spinal subarachnoid perfusions in dogs: a method for determining CSF dynamics under non-steady state conditions
39. Erythrocyte substitute for perfusion of brain
40. Cerebral metabolism following brain injury: II. Lactic acid changes
41. Hemodynamic and oxygen transport effects of a perfluorochemical blood substitute, Fluosol-DA (20%)
42. Cerebrospinal fluid may nourish cerebral vessels through pathways in the adventitia that may be analogous to systemic vasa vasorum