G2 chromosomal radiosensitivity of ataxia-telangiectasia heterozygotes

Cancer Genetics and Cytogenetics

Volumn 14, Issue 1-2, 1985, Pages 163-168

  Parshad, Ram ^a   Sanford, Katherine K ^b   Jones, Gary M ^b   Tarone, Robert E ^b  

^a HOWARD UNIVERSITY COLLEGE OF MEDICINE   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; ATAXIA TELANGIECTASIA; CELL LINE; CHROMATID; CYTOLOGY; FIBROBLAST; GENETICS; HETEROZYGOTE; HUMAN; INTERPHASE; KARYOTYPING; METAPHASE; PATHOLOGY; RADIATION EXPOSURE; SKIN; CELL CYCLE G2 PHASE; CHROMOSOME ABERRATION; CONGENITAL DISORDER; DNA REPAIR; ETIOLOGY; HEREDITY; HISTOLOGY; HUMAN CELL; IN VITRO STUDY; MAJOR CLINICAL STUDY; NERVOUS SYSTEM; PRIORITY JOURNAL; RADIOSENSITIVITY;

ATAXIA TELANGIECTASIA; CELL LINE; CHROMATIDS; FIBROBLASTS; HETEROZYGOTE; HUMAN; INTERPHASE; KARYOTYPING; METAPHASE; SKIN;

EID: 0021893817     PISSN: 01654608     EISSN: None     Source Type: Journal    
DOI: 10.1016/0165-4608(85)90227-4     Document Type: Article

References (30)

1. Malignant neoplasms in the families of patients with ataxia-telengiectasia
2. Ataxia-telangiectasia. A familial syndrome of progressive cerebellar ataxia, oculocutaneous telengiectasia and frequent pulmonary infection
3. Progressive degenerative disease associated with defective DNA repair: xeroderma pigmentosum and ataxia telangiectasia
4. Specific chromosome aberrations in ataxia telangiectasia
5. Ataxia telangiectasia: A human mutation with abnormal radiation sensitivity
6. Unrepaired DNA strand breaks in irradiated ataxia telangiectasia lymphocytes suggested from cytogenetic observations
7. Chromosomal radiosensitivity of ataxia telangiectasia cells at different cycle stages
8. Effects of the DNA strand-cleaving antitumor agent, streptonigrin, on ataxia telangiectasia cells
9. The cytogenetic response of Fanconi's anemia lymphoblastoid cell lines to various clastogens
10. Unusual levels of (ADP-ribose) and DNA synthesis in ataxia telangiectasia cells following γ-irradiation
11. Radiosensitivity in ataxia telangiectasia A new explanation
12. Identification of ataxia telangiectasia heterozygotes, a cancer prone population
13. Ataxia telangiectasia heterozygotes: dominant expression of ionizing radiation sensitive mutants
14. Enhanced radiosensitivity of cultured fibroblasts from ataxia telangiectasia heterozygotes manifested by defective colonyforming ability and reduced DNA repair replication after hypoxic γ-irradiation
15. Radiosensitivity in Huntington's disease: Implications for pathogenesis and presymptomatic diagnosis
16. Cellular hypersensitivity to neocarzinostatin in ataxia-telangiectasia skin fibroblasts
17. Susceptibility to fluorescent light-induced chromatid breaks associated with DNA repair deficiency and malignant transformation in culture
18. 2 phase in a line of normal human fibroblasts and its malignant derivative
19. Neoplastic transformation of human cells in culture associated with deficient repair of light-induced chromosomal DNA damage
20. 2
21. 2 chromosomal radiosensitivity in Fanconi's anemia
22. 2 phase x-irradiation of cells from cancer-prone individuals implicates deficiency in DNA repair
23. Neoplastic transformation of human diploid fibroblast cells by chemical carcinogens
24. Light-induced chromatid damage in human skin fibroblasts in culture in relation to their neoplastic potential
25. Effect of intensity and wavelength of fluorescent light on chromosome damage in cultured mouse cells
26. Fluorescent light-induced DNA crosslinkage and chromatid breaks in mouse cells in culture
27. Attempts to detect ataxia telangiectasia (AT) heterozygotes by cytogenetical techniques
28. Increased level of bleomycin-induced chromosome breakage in ataxia telangiectasia skin fibroblasts