Direct mutagenesis of Ha-ras-1 oncogenes by N-nitroso-N-methylurea during initiation of mammary carcinogenesis in rats

Nature

Volumn 315, Issue 6018, 1985, Pages 382-385

  Zarbl, Helmut ^a   Sukumar, Saraswati ^a   Arthur, Anne V ^a   Martin Zanca, Dionisio ^a   Barbacid, Mariano ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

METHYLNITROSOUREA; RADIOISOTOPE;

ANIMAL EXPERIMENT; BREAST; BREAST CANCER; ETIOLOGY; GENE ACTIVATION; GENETIC ENGINEERING; HEREDITY; MUTAGENESIS; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; ONCOGENE; PRIORITY JOURNAL; RAT;

9,10-DIMETHYL-1,2-BENZANTHRACENE; ANIMALS; BASE SEQUENCE; FEMALE; MAMMARY NEOPLASMS, EXPERIMENTAL; METHYLNITROSOUREA; MUTATION; NITROSOUREA COMPOUNDS; ONCOGENES; RATS;

ANIMALIA;

EID: 0021871265     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/315382a0     Document Type: Article

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