Effects of Combined Treatment with Interferon and Mezerein on Melanogenesis and Growth in Human Melanoma Cells

Journal of Interferon Research

Volumn 5, Issue 1, 1985, Pages 11-22

  Fisher, Paul B ^a   Prignoli, Diane R ^a   Hermo, Henry ^a   Weinstein, I Bernard ^a   Pestka, Sidney ^b  

^a Columbia University College of Physicians and Surgeons ^*  (United States)

^b HOFFMANN LA ROCHE INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4ALPHA PHORBOL DIDECANOATE; DIMETHYL SULFOXIDE; INTERFERON; MELANIN; MEZEREIN; PHORBOL; PHORBOL 13 ACETATE 12 MYRISTATE; RECOMBINANT ALPHA INTERFERON A; RECOMBINANT ALPHA INTERFERON AD; RECOMBINANT ALPHA INTERFERON D; RECOMBINANT BETA INTERFERON; UNCLASSIFIED DRUG;

ARTICLE; CANCER IMMUNOTHERAPY; DRUG EFFICACY; HUMAN; HUMAN CELL; MELANOMA CELL; PRIORITY JOURNAL; THERAPY; TUMOR CELL; TUMOR DIFFERENTIATION;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL DIFFERENTIATION; CELL DIVISION; CELL LINE; DITERPENES; DRUG SYNERGISM; HUMANS; INTERFERON TYPE I; MELANINS; MELANOMA; TERPENES;

EID: 0021848970     PISSN: 01978357     EISSN: 15577465     Source Type: Journal    
DOI: 10.1089/jir.1985.5.11     Document Type: Article

References (62)

1. GRESSER, I. (1977). On the varied biologic effects of interferon. Cell. Immunol. 34, 406–415.
2. TAYLOR-PAPADIMITRIOU, J. (1980). Effect of interferons on cell-growth and function, in: Interferon. I. Gresser (ed.). Academic, New York, Vol. 2, pp. 13–46.
3. FISHER, P.B. and GRANT, S. (1984). Effects of interferon on differentiation in normal and tumor cells, in: Pharmacology and Therapeutics, Part A: Chemotherapy, Toxicology and Metabolic Inhibitors. A.C. Sartorelli (ed.). Pergamon Press, England, New York (in press).
4. FISHER, P.B., HERMO, H., Jr., PRIGNOLI, D.R., WEINSTEIN, I.B., and PESTKA, S. (1984). Hybrid recombinant human leukocyte interferon inhibits differentiation in murine B-16 melanoma cells. Biochem. Biophys. Res. Commun. 119, 108–115.
5. ROSSI, G.B., DOLEI, A., CIOE, L., BENEDETTO, A., MATARESE, G.P., and BELARDELLI, F. (1977). Inhibition of transcription and translation of globin messenger RNA in dimethyl sulfoxide-stimulated Friend erythroleukemic cells treated with interferon. Proc. Natl. Acad. Sci. USA 74, 2036–2040.
6. ROSSI, G.B., MATARESE, G.P., GRAPPELLI, C., BELARDELLI, F., and BENEDETTO, A. (1977). Interferon inhibits dimethyl sulphoxide-induced erythroid differentiation of Friend leukemia cells. Nature (London) 267, 50–52.
7. CIOE, L., O'BRIEN, T.G., and DIAMOND, L. (1980). Inhibition of adipose conversion of Balb-C 3T3 cells by interferon and 12-O-tetradecanoylphorbol-13-acetate. Cell Biol. Int. Rep. 4, 255–264.
8. KEAY, S. and GROSSBERG, S.E. (1980). Interferon inhibits the conversion of 3T3-L1 mouse fibroblasts into adipocytes. Proc. Natl. Acad. Sci. USA 77, 4099–4103.
9. FISHER, P.B., MUFSON, R.A., and WEINSTEIN, I.B. (1981). Interferon inhibits melanogenesis in B-16 mouse melanoma cells. Biochem. Biophys. Res. Commun. 100, 823–830.
10. TOMIDA, M., YAMAMOTO, Y., and HOZUMI, M. (1982). Stimulation by interferon of induction of differentiation of human promyelocytic leukemia cells. Biochem. Biophys. Res. Commun. 104, 30–37.
11. LOUGH, J., KEAY, S., SABRAN, J.L., and GROSSBERG, S.E. (1982). Inhibition of chicken myogenesis in vitro by partially purified interferon. Biochem. Biophys. Res. Commun. 109, 92–99.
12. FISHER, P.B., MIRANDA, A.F., BABISS, L.E., PESTKA, S., and WEINSTEIN, I.B. (1983). Opposing effects of interferon produced in bacteria and of tumor promoters on myogenesis in human myoblast cultures. Proc. Natl. Acad. Sci. USA 80, 2961–2965.
13. WEINSTEIN, I.B., LEE, L.S., FISHER, P.B., MUFSON, R.A., and YAMASAKI, H. (1979). Action of phorbol esters in cell -culture - mimicry of transformation, altered differentiation, and effects on cell-membranes. J. Supramol. Struct. 12, 195–208.
14. FISHER, P.B. (1984). Enhancement of viral transformation and expression of the transformed phenotype by tumor promoters, in: Tumor Promotion and Carcinogenesis In Vitro, Mechanisms of Tumor Promotion. T.J. Slaga (ed.). CRC Press, Florida, pp. 57–123.
15. YAMASAKI, H., FIBACH, E., NUDEL, U., WEINSTEIN, I.B., RIFKIND, R.A., and MARKS, P.A. (1977). Tumor promoters inhibit spontaneous and induced differentiation of murine erythroleukemia cells in culture. Proc. Natl. Acad. Sci. USA 74, 3451–3455.
16. ROVERA, G., O'BRIEN, T.G., and DIAMOND, L. (1977). Tumor promoters inhibit spontaneous differentiation of Friend erythroleukemia cells in culture. Proc. Natl. Acad. Sci. USA 74, 2894–2898.
17. ISHII, D.N., FIBACH, E., YAMASAKI, H., and WEINSTEIN, I.B. (1979). Tumor promoters inhibit morphological differentiation in cultured mouse neuroblastoma cells. Science 200, 556–559.
18. MUFSON, R.A., FISHER, P.B., and WEINSTEIN, I.B. (1979). Effect of phorbol ester tumor promoters on the expression of melanogenesis in B-16 melanoma cells. Cancer Res. 39, 3915–3919.
19. MUFSON, R.A., FISCHER, S.M., VERMA, A.K., GLEASON, G.L., SLAGA, T.J., and BOUTWELL, R.K. (1979). Effects of 12–0-teradecanoylphorbol-13-acetate and mezerein on epidermal ornithine decarb-oxylase activity, isoproterenol-stimulated levels of cyclic adenosine 3′:5′-monophosphate, and induction of mouse skin tumors in vivo. Cancer Res. 39, 4791–4795.
20. SLAGA, T.J., FISCHER, S.M., NELSON, K., and GLEASON, G.L. (1980). Studies on the mechanism of skin tumor promotion: evidence for several stages in promotion. Proc. Natl. Acad. Sci. USA 77, 3659–3663.
21. SLAGA, T.J., KLEIN-SZANTO, A.J.P., FISCHER, S.M., WEEKS, C.E., NELSON, K., and MAJOR, S. (1980). Studies on mechanism of action of anti-tumor-promoting agents: their specificity in two-stage promotion. Proc. Natl. Acad. Sci. USA 77, 2251–2254.
22. PESTKA, S. (1983). The human interferons from protein purification and sequence to cloning and expression in bacteria: before, between, and beyond. Arch. Biochem. Biophys. 221, 1–37.
23. BRADLEY, E.C. and RUSCETTI, F.W. (1981). Effect of fibroblast, lymphoid, and myeloid interferons on human tumor colony formation in vitro. Cancer Res. 41, 244–249.
24. GRANT, S., BHALLA, K., WEINSTEIN, I.B., PESTKA, S., and FISHER, P.B. (1982). Differential effect of recombinant human leukocyte interferon on human leukemia and normal myeloid progenitor cells. Biochem. Biophys. Res. Commun. 108, 1048–1055.
25. FISH, E.N., BANERJEE, K., and STEBBING, N. (1983). Human-leukocyte interferon subtypes have different anti-proliferative and antiviral activities on human cells. Biochem. Biophys. Res. Commun. 112, 537–546.
26. EVINGER, M., RUBINSTEIN, M., and PESTKA, S. (1981). Antiproliferative and antiviral activities of human leukocyte interferons. Arch. Biochem. Biophys. 210, 319–329.
27. PESTKA, S., KELDER, B., REHBERG, E., ORTALDO, J.R., HERBERMAN, R.B., KEMPNER, E.S., MOSCHERA, J.A., and TARNOWSKI, S.J. (1983). The specific molecular activities of interferons differ for antiviral, anti-proliferative, and natural killer cell activities, in: The Biology of the Interferon System 1983. e. DeMaeyer and H. Schellekens (eds.). Elsevier Science Publishers B.V., pp. 535–549.
28. MAKOVER, S.D., TELEP, E., and WRIGHT, R.B. (1981). Antiproliferative activity of human leukocyte interferon. Abstract, Second Annual Congress for Interferon Research, San Francisco, CA, Oct. 21–31, 1981.
29. STRANDER, H., CANTELL, K., CARLSTROM, G., and JAKOBSSON, P.A. (1973). Clinical and laboratory investigations on man: systemic administration of potent interferon to man. J. Natl. Cancer Inst. 51, 733–742.
30. MERIGAN, T.C., RAND, K.H., POLLARD, R.B., ABDALLAH, P.S., JORDAN, G.W., and FRIED, R.P. (1978). Human leukocyte interferon for the treatment of herpes zoster in patients with cancer. N. Eng. J. Med. 298, 981–987.
31. GUTTERMAN, J.U., BLUMENSCHEIN, G.R., ALEXANIAN, R., YAP, H.Y., BUZDAR, A.U., CABANILLAS, F., HORTOBAGYI, G.N., HERSCH, E.M., RASMUSSEN, S.L., HARMON, M., KRAMER, M., and PESTKA, S. (1980). Leukocyte interferon-induced tumor regression in human metastatic breast cancer, multiple myeloma, and malignant lymphoma. Ann. Intern. Med. 93, 399–406.
32. GUTTERMAN, J.U., FINE, S., QUESADA, J., HORNING, S.J., LEVINE, J.F., ALEXANIAN, R., BERNHARDT, L., KRAMER, M., SPIEGEL, H., COLBURN, W., TROWN, P., MERIGAN, T., and DZIEWANOWSKA, Z. (1982). Recombinant leukocyte A interferon: pharmacokinetics, single-dose tolerance and biologic effects in cancer patients. Ann. Intern. Med. 96, 549–556.
33. QUESADA, J.R., SWANSON, D.A., TRINDADE, A., and GUTTERMAN, J.U. (1983). Renal cell carcinoma: antitumor effects of leukocyte interferon. Cancer Res. 43, 940–947.
34. GIOVANELLA, B.C., STEHLIN, J.S., SANTAMARIA, C., YIM, S.O., MORGAN, A.C., WILLIAMS, L.J., LEIBOVITZ, A., FIALKOW, P.Y., and MUMFORD, D.M. (1976). Human neoplastic and normal cells in tissue culture. I. Cell lines derived from malignant melanomas and normal melanocytes. J. Natl. Cancer Inst. 56, 1131–1142.
35. FISHER, P.B., GOLDSTEIN, N.I., BONNER, D.P., MECHLINSKI, W., BRYSON, V., and Schaff-NER, C.P. (1975). Toxicity of amphotericin B and its methyl ester toward normal and tumor cell lines. Cancer Res. 35, 1996–1999.
36. WHITTAKER, J.R., (1963). Changes in melanogenesis during the dedifferentiation of chick retinal pigment cells in cell cultures. Dev. Biol. 8, 99–127.
37. GOEDDEL, D.V., YELVERTON, E., ULRICH, A., HEYNEKER, H.L., MIOZZARI, G., HOLMES, W., SEEBURG, P.H., DULL, T., MAY, L., STEBBING, N., CREA, R., MAEDA, S., McCANDLISS, R., SLOMA, A., TABOR, J.M., GROSS, M., FAMILLETTI, P.C., and PESTKA, S. (1980). Human leukocyte interferon produced by E. coli is biologically active. Nature (London) 287, 411–416.
38. REHBERG, E., KELDER, B., HOAL, E.G., and PESTKA, S. (1982). Specific molecular activities of recombinant and hybrid leukocyte interferons. J. Biol. Chem. 257, 11497–11502.
39. GOEDDEL, D.V., SHEPARD, H.M., YELVERTON, E., LEUNG, D., CREA, R., SLOMA, A., and PESTKA, S. (1980). Synthesis of human fibroblast interferon by E. coli. Nucleic Acids Res. 8, 4057–4074.
40. STAEHLIN, T., HOBBS, D.S., KUNG, H.F., LAI, C.Y., and PESTKA, S. (1981). Purification and characterization of recombinant human leukocyte interferon (IFLrA) with monoclonal antibodies. J. Biol. Chem. 256, 9750–9754.
41. STEIN, S., KENNY, C, FRIESEN, H.J., SHIVELY, J., DEL VALLE, U., and PESTKA, S. (1980). NH2-terminal amino-acid sequence of human fibroblast interferon. Proc. Natl. Acad. Sci. USA 77, 5716–5719.
42. KENNY, C, MOSCHERA, J.A., and STEIN, S. (1981). Purification of human fibroblast interferon produced in the absence of serum by cibacon blue F3GA-agarose and high-performance liquid chromatography, in: Methods in Enzymology. S. Pestka (ed.). Academic Press, New York, Vol. 78, pp. 435–447.
43. RUBINSTEIN, S., FAMILLETTI, P.C., and PESTKA, S. (1981). Convenient assay for interferons. J. Virol. 37, 755–758.
44. HUBERMAN, E., HECKMAN, C., and LANGENBACH, R. (1979). Stimulation of differentiated functions in human melanoma cells by tumor-promoting agents and dimethyl sulfoxide. Cancer Res. 39, 2618–2624.
45. BELLET, R.E., BERD, D., and MASTRANGELO, M.J. (1979). Chemotherapy of malignant melanoma, in: Human Malignant Melanoma. W.H. Clark, Jr., L.I. Goldman, and M.J. Mastrangelo (eds.). Grune and Stratton, New York.
46. KIRKWOOD, J.M. and MARSH, J.C. (1983). In vivo drug sensitivity assay of clonogenic human melanoma cells and correlation with treatment outcome. Cancer Res. 43, 3434–3440.
47. KOHNO, M., IDA, N., NAGAO, S., TANAKA, N., SEKIGUCHI, F., UENISHI, N., KAJITA, A., and OGAWA, H. (1982). Effects of human fibroblast interferon on human-tumors transplanted into nude mice-sensitivity of human-tumors to interferon. Gann 73, 945–951.
48. IDA, N., UENISCHI, N., KAJITA, A., and SATOH, Y. (1982). Anti-tumor effect of human fibroblast interferon on the growth of human-melanoma cells implanted in nude-mice. Gann 73, 952–960.
49. BRANCA, A.A. and BAGLIONI, C. (1981). Evidence that Type-I and Type-II interferons have different receptors. Nature 294, 768–770.
50. MOGENSEN, K.E., BANDU, M.T., VIGNAUX, F., AGUET, M., and GRESSER, I. (1981). Binding of 125I-labelled human interferon to human lymphoid cells. Int. J. Cancer 28, 575–582.
51. BAGLIONI, C., BRANCA, A.A., D'ALESSANDRO, S.B., HOSSENLOPP, D., and CHADHA, K.C. (1982). Low interferon binding activity of two human cell lines which respond poorly to the antiviral and antiproliferative activity of interferon. Virol. 122, 202–206.
52. ZOON, K.C., ZUR NEDDEN, D., and ARNHEITER, H. (1982). Specific binding of human α interferon to a high affinity cell surface binding site on bovine kidney cells. J. Biol. Chem. 257, 4695–4697.
53. DREIDGER, P.E. and BLUMBERG, P.M. (1980). Specific binding of phorbol ester tumor promoters. Proc. Natl. Acad. Sci. USA 77, 567–571.
54. SHOYAB, M. and TODARO, G.J. (1980). Specific high affinity cell membrane receptors for biologically active phorbol and ingenol esters. Nature (London) 288, 451–455.
55. HOROWITZ, A.D., GREENEBAUM, E., and WEINSTEIN, I.B. (1981). Identification of receptors for phorbol ester tumor promoters in intact mammalian cells and of an inhibitor of receptor binding in biologic fluids. Proc. Natl. Acad. Sci. USA 78, 2315–2319.
56. FISHER, P.B., COGAN, U., HOROWITZ, A.D., SCHACHTER, D., and WEINSTEIN, I.B. (1981). TPA-resistance in Friend erythroleukemia cells: role of membrane lipid fluidity. Biochem. Biophys. Res. Commun. 100, 370–376.
57. FISHER, P.B., FLAMM, M., SCHACHTER, D., and WEINSTEIN, I.B. (1979). Tumor promoters induce membrane changes detected by fluorescence polarization. Biochem. Biophys. Res. Commun. 86, 1062–1068.
58. CASTAGNA, M., ROCHETTE-EGLY, C., ROSENFELD, C., and MISHAL, Z. (1979). Altered lipid microviscosity in lymphoblastoid cells treated with 12-O-tetradecanoyl phorbol 13-acetate, a tumor promoter. FEBS Lett. 100, 62–66.
59. KUHRY, J.G., POINDRON, P., and LAUSTRIAT, G. (1983). Evidence for early fluidity changes in the plasma membranes of interferon treated L cells, from fluorescence anisotrophy data. Biochem. Biophys. Res. Commun. 110, 88–95.
60. FISHER, P.B., SCHACHTER, D., ABBOTT, R.E., CALLAHAM, M.F., and HUBERMAN, E. (1984). Membrane lipid dynamics in human promyelocytic leukemia cells sensitive and resistant to 12-O-tetra-decanoyl-phorbol-13-acetate induction of cell differentiation. Cancer Res. 44, 5550–5554.
61. WEINSTEIN, I.B. (1983). Protein kinase, phospholipids and control of growth. Nature 302, 750.
62. GRANT, S., MILENO, M.D., WEINSTEIN, I.B., PESTKA, S., and FISHER, P.B. (1983). Interferon enhances growth suppression induced by retinoic acid and phorbol ester tumor promoters in sensitive and resistant HL-60 myeloid leukemia cells. Blood 62, 503.