Induction of drug metabolizing enzymes in human liver cell line Hep G2

FEBS Letters

Volumn 183, Issue 2, 1985, Pages 219-222

  Dawson, J R ^a   Adams, D J ^b   Wolf, C R ^b  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b WESTERN GENERAL HOSPITAL   (United Kingdom)

Author keywords

Cell line; Cytochrome; Drug metabolism; Enzyme induction; Hep G2; P 450; UDP glucoronosyltransferase

Indexed keywords

3 METHYLCHOLANTHRENE; 7 ETHOXYCOUMARIN; PHENOBARBITAL; UMBELLIFERONE;

CELL STRAIN HEPG2; DOSE RESPONSE; DRUG MECHANISM; DRUG METABOLISM; DRUG RESPONSE; ENZYME INDUCTION; GENE CONTROL; HEREDITY; HUMAN; IN VITRO STUDY; LIVER; LIVER CELL CULTURE; PRIORITY JOURNAL;

CELL LINE; COUMARINS; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME INDUCTION; GLUCURONOSYLTRANSFERASE; HUMAN; ISOENZYMES; LIVER; METHYLCHOLANTHRENE; PHARMACEUTICAL PREPARATIONS; PHENOBARBITAL; SULFURTRANSFERASES;

EID: 0021846279     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-5793(85)80780-8     Document Type: Article

References (19)

1. Identification of human cytochromes P-450 analogous to forms induced by phenobarbital and 3-methylcholanthrene in the rat.