A therapeutic trial with low-dose cytarabine in myelodysplastic syndromes and acute leukemia

Acta Haematologica

Volumn 73, Issue 2, 1985, Pages 71-74

  Inbal, A ^a   Januszewicz, E ^a   Rabinowictz, M ^a   Shaklai, M ^a  

^a TEL AVIV UNIVERSITY   (Israel)

Author keywords

Low dose cytarabine; Myelodysplastic syndromes

Indexed keywords

CYTARABINE; DAUNORUBICIN; THROMBOCYTE CONCENTRATE;

ACUTE LEUKEMIA; ADVERSE DRUG REACTION; ANEMIA; BLOOD AND HEMOPOIETIC SYSTEM; BONE MARROW CELL; BONE MARROW DISEASE; CANCER CHEMOTHERAPY; CASE REPORT; CLINICAL ARTICLE; DRUG DOSE; DRUG EFFICACY; DRUG INDICATION; DRUG THERAPY; ERYTHROCYTE CONCENTRATE; HISTOLOGY; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; METHODOLOGY; MYELODYSPLASIA; PRIORITY JOURNAL; THERAPY;

ACUTE DISEASE; AGED; BONE MARROW DISEASES; CLINICAL TRIALS; CYTARABINE; DRUG ADMINISTRATION SCHEDULE; HUMAN; LEUKEMIA; MIDDLE AGE; SYNDROME; TIME FACTORS;

EID: 0021823862     PISSN: 00015792     EISSN: 14219662     Source Type: Journal    
DOI: 10.1159/000206283     Document Type: Article

References (11)

1. Bennett, J.M.; Catovsky, D.; Daniel, M.T.; Flandrin, G.; Galton, D.A.G.; Gralnick, H.R.; Sultan, C.: Proposals for the classification of the myelodysplastic syndromes. Br. J. Haemat. 51: 189-199 (1982).
2. Editorial: Treatment for preleukemia. Lancet i: 943-944 (1984).
3. Cooperative Group for the Study of Aplastic and Refractory Anemias. Retreatment with androgens or cytosine arabinoside: results of a prospective trial in 58 patients. Cancer 44: 1976-1982 (1979).
4. Lotem, J.; Sachs, L.: Different blocks in the differentiation of myeloid leukemia cells. Proc. natn. Acad. Sci. USA 71: 3507-3511 (1974).
5. Griffin, J.; Munroe, D.; Major, P.; Kufe, D.: Induction of differentiation of human myeloid leukemia cells by inhibition of DNA synthesis. Exp. hematol. 10: 774-781 (1982).
6. Moloney, W.C.; Rosenthal, D.S.: Treatment of early acute nonlymphocytic leukemia with low-dose cytosine arabinoside. Haematol. Blood Transfus. 26: 59-62 (1981).
7. Baccarani, M.; Tura, S.: Differentiation of myeoloid leukaemic cells: new possibilities for therapy. Br. J. Haemat. 42: 485-487 (1979).
8. Housset, M.; Daniel, M.T.; Degos, L.: Small doses of ARA-C in the treatment of acute myeloid leukaemia: differentiation of myeloid leukaemia cells?. Br. J. Haemat. 51: 125-129 (1982).
9. Wisch, J.; Griffin, J.; Kufe, D.: Response of preleukemic syndromes to continuous infusion of low-dose cytarabine. New Engl. J. Med. 309: 1599-1602 (1983).
10. Seabright, M.: Rapid binding technique for human chromosomes. Lancet ii: 971-972 (1971).
11. Castaigne, S.; Daniel, M.T.; Tilly, H.; Herait, P.; Degos, L.: Does treatement with ARA-C in low dosage cause differentiation of leukemic cells? Blood 62: 85-86 (1983)