Action of camptothecin and its derivatives on deoxyribonucleic acid

Biochemical Pharmacology

Volumn 34, Issue 8, 1985, Pages 1225-1230

  Fukada, Masako ^a  

^a AICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALOID; ANTINEOPLASTIC AGENT; CAMPTOTHECIN; CAMPTOTHECIN DERIVATIVE; DNA; POLY(DEOXYADENYLATE DEOXYTHYMIDYLATE); RADIOISOTOPE;

BIOLOGICAL MODEL; CAMPTOTHECIN H 3; CANCER CHEMOTHERAPY; DOSE RESPONSE; DRUG BINDING; DRUG MECHANISM; DRUG RESPONSE; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; THERAPY;

ALKALIES; CAMPTOTHECIN; DNA; DNA, SUPERHELICAL; NUCLEIC ACID CONFORMATION; NUCLEIC ACID DENATURATION; OSMOLAR CONCENTRATION; SPECTROPHOTOMETRY, ULTRAVIOLET; STRUCTURE-ACTIVITY RELATIONSHIP; SUPPORT, NON-U.S. GOV'T;

EID: 0021799944     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-2952(85)90499-X     Document Type: Article

References (33)

1. The effects of camptothecin on mammalian DNA
2. A Selective One-step Introduction of Hydroxylic Functions at the C-5 and C-7 Positions of 20(S)-Camptothecin, an Alkaloid Having Antitumor Activity
3. Chemical Modification of Antitumor Alkaloid Camptothecin. Acid-Catalyzed Conversion of 7-Hydroxymethylcamptothecin into the Aldehyde and Its Acetals
4. Sedimentation velocity behavior of closed circular SV40 DNA as a function of superhelix density, ionic strength, counterion and temperature
5. THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS