Authentic T helper CD4 (W3/25) antigen on rat peritoneal macrophages

Journal of Experimental Medicine

Volumn 162, Issue 1, 1985, Pages 117-127

  Jefferies, Wilfred A ^a   Green, Jon R ^a   Williams, Alan F ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

MONOCLONAL ANTIBODY;

HELPER CELL; IMMUNOPRECIPITATION; LYMPHATIC SYSTEM; MACROPHAGE ANTIGEN; NONHUMAN; PERITONEUM; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; RAT; T LYMPHOCYTE; T4 ANTIGEN;

ANIMAL; ANTIBODIES, MONOCLONAL; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; ANTIGENS, SURFACE; ASCITIC FLUID; COMPARATIVE STUDY; HUMAN; IN VITRO; LYMPHOCYTE ACTIVATION; MACROPHAGES; MICE; RATS; SPECIES SPECIFICITY; T-LYMPHOCYTES, HELPER-INDUCER;

EID: 0021796697     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.162.1.117     Document Type: Article

References (31)

1. Williams, A. F., G., Galfré, and C. Milstein. 1977. Analysis of cell surfaces by xenogeneic myeloma-hybrid antibodies: differentiation antigens of rat lymphocytes. Cell. 12:663.
2. White, R. A. H., D. W. Mason, A. F. Williams, G. Galfré, and C. Milstein. 1978. Tlymphocyte heterogeneity in the rat: separation of functional subpopulations using a monoclonal antibody. J. Exp. Med. 148:664.
3. Bernard, A, L. Bounsell, J. Dausset, C. Miistein, and S. F. Schlossman, editors. 1984. Leucocyte Typing. Springer-Verlag, Heidelberg. 45-48.
4. Wilde, D. B., P. Marrack, J. Kappler, D. P. Dialynas, and F. W. Fitch. 1983. Evidence implicating L3T4 in class II MHC antigen reactivity: monoclonal antibody GK1.5 (anti-L3T4a) blocks class II MHC antigen-specific proliferation, release of lymphokines, and binding by cloned murine helper T lymphocyte lines. J. Immunol. 131:2178.
5. Dialynas, D. P., Z. S. Quan, K. A. Wall, A. Pierres, J. Quintáns, M. R. Loken, M. Pierres, and F. W. Fitch. 1983. Characterization of the murine T cell surface molecule, designated L3T4, identified by monoclonal antibody GK1.5: similarity of L3T4 to the human Leu-3/T4 molecule. J. Immunol. 131:2445.
6. Thomas, M. L., andJ. R. Green. 1983. Molecular nature of the W3]25 and MRC OX-8 marker antigens for rat T lymphocytes: comparisons with mouse and human antigens. Eur. J. Immunol. 13:855.
7. Webb, M., D. W. Mason, and A. F. Williams. 1979. Inhibition of the mixed lymphocyte response with a monoclonal antibody specific for a rat T lymphocyte subset. Nature (Lond.). 282:841.
8. Mason, D. W., C. W. Pugh, and M. Webb. 1981. The rat mixed lymphocyte reaction:roles of a dendritic cell in intestinal lymph and T-cell subsets defined by monoclonal antibodies. Immunology. 44:75.
9. Watts, T.H., A. A. Brian, J. W. Kappler, P. Marrack, and H. M. McConnell. 1984. Antigen presentation by supported planar membranes containing affinity-purified I-A d. Proc. Natl. Acad. Sci. USA. 81:7564.
10. Greenstein, J. L., J. Kappler, P. Marrack, and S. F. Burakoff. 1984. The role of L3T4 in recognition of Ia by a cytotoxic, H-2Dd-specific T cell hybridoma. J. Exp. Med. 159:1213.
11. Barclay, A. N. 1981. The localization of populations of lymphocytes defined by monoclonal antibodies in rat lymphoid tissues. Immunology. 42:593.
12. Wood, G. S., N. L. Warner, and R. A. Warnke. 1983. Anti-Leu-3/T4 antibodies react with cells of monocyte-macrophage and Langerhans lineage. J. Immunol. 131:212.
13. Moscicki, R. A., E. P. Amento, S. M. Krane, J. T. Kurnick, and R. B. Colvin. 1983. Modulation of surface antigens of a human monocyte cell line, U937, during incubation with T lymphocyte-conditioned medium: detection of T4 antigen and its presence on normal blood monocytes. J. Immunol. 131:743.
14. Galfré, G., and C. Milstein. 1981. Preparation of monoclonal antibodies: strategies and procedures. Methods. Enzymol. 73:3.
15. McMaster, W. R., and A. F. Williams. 1979. Identification of Ia glycoproteins in rat thymus and purification from rat spleen. J. Immunol. 9:426.
16. Hunt, S. V., and M. H. Fowler. 1981. A repopulation assay for B and T lymphocyte stem cells employing radiation chimaeras. Cell Tissue Kinet. 14:445.
17. Dallman, M.J., M. L. Thomas, andJ. R. Green. 1984. MRC OX-19: a monoclonal antibody that labels rat T lymphocytes and augments in vitro proliferative responses. Eur. J. lmmunol. 14:260.
18. Hsiung, L.-M., A. N. Barclay, M. R. Brandon, E. Sire, and R. R. Porter. 1982. Purification of human C3b inactivator by monoclonal-antibody affinity chromatography. Biochem. J. 203:293.
19. Barnstable, C. J., W. F. Bodmer, G. Brown, G. Galfré, C. Milstein, A. F. Williams, and A. Ziegler. 1978. Production of monoclonal antibodies to Group A erythrocytes, HLA, and other human cell surface antigens--new tools for genetic analysis. Cell. 14:9.
20. Spickett, G. P., M. R. Brandon, D. W. Mason, A. F. Williams, and G. R. Woollett. 1983. MRC OX-22, a monoclonal antibody that labels a new subset ofT lymphocytes and reacts with the high molecular weight form of the leukocyte-common antigen. J. Exp. Med. 158:795.
21. Woollett, G. R., A. N. Barclay, M. Puklavec, and A. F. Williams. 1985. Molecular and antigenic heterogeneity of the rat leucocyte-common antigen from thymocytes and T and B iymphocytes. Eur.J. lmmunol. 15:168.
22. Mason, D. W., and A. F. Williams. 1980. The kinetics of antibody binding to membrane antigens in solution and at the cell surface. Biochem. J. 187:1.
23. Mason, D. W. 1981. Subsets of T cells in the rat mediating lethal graft-versus-host disease. Transplantation (Baltimore). 32:222.
24. Ford, W. L. 1978. The preparation and labeling of lymphocytes. In Handbook of Experimental Immunology. D. M. Weir, editor. Blackwell Scientific Publications, Oxford, England. Third ed. 2:1-26.
25. Jefferies, W. A., M. R. Brandon, A. F. Williams, and S. V. Hunt. 1985. Analysis of lymphopoietic stem cells with a monoclonal antibody to the rat transferrin receptor. Immunology. 54:333.
26. Dallman, M.J., D. W. Mason, and M. Webb. 1982. The roles of host and donor cells in the rejection of skin allografts by T cell-deprived rats injected with syngeneic T cells. Eur. J. Immunol. 12:511.
27. Mason, D. W., R. P. Arthur, M.J. Dallman, J. R. Green, G. P. Spickett, and M. L. Thomas. 1983. Functions of rat T-lymphocyte subsets isolated by means of monoclonal antibodies. Immunol. Rev. 74:57.
28. Nilsson, S. F., and M. J. Waxdal. 1976. Isolation and identification of the major concanavalin A-binding glycoproteins from murine lymphocytes. Biochemistry. 15:2698.
29. Steueger, B., J. Klempnauer, and K. Worngeit. 1984. Phenotype and histological distribution of interstitial dendritic cells in the rat pancreas, liver, heart and kidney. Transplantation (Baltimore). 38:169.
30. Steinman, R. M., and M. C. Nussenzweig. 1980. Dendritic cells: features and functions. Immunol. Rev. 53:127.
31. + cytotoxic T cells can lyse targets via class I molecules and can be blocked by monoclonal antibody against T4 molecules. J. Immunol. 133:1705.