(E,Z)-Ajoene: A Potent Antithrombotic Agent from Garlic

Journal of the American Chemical Society

Volumn 106, Issue 26, 1984, Pages 8295-8296

  Block, Eric ^a   Ahmad, Saleem ^a   Jain, Mahendra K ^b   Crecely, Roger W ^b   Apitz Castro, Rafael ^c   Cruz, Maria R ^c  

^a STATE UNIVERSITY OF NEW YORK   (United States)

^b UNIVERSITY OF DELAWARE   (United States)

^c INSTITUTO VENEZOLANO DE INVESTIGACIONES CIENTÍFICAS   (Venezuela)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMICAL ENGINEERING;

AJOENE; ANTITHROMBOTIC AGENT; ATHEROSCLEROSIS; GARLIC; STROKE;

BIOCHEMISTRY;

AJOENE; COLLAGEN; NEW DRUG;

2 VINYL 4H 1,3 DITHIIN; ANIMAL CELL; ANIMAL EXPERIMENT; BLOOD AND HEMOPOIETIC SYSTEM; DRUG ANALYSIS; DRUG IDENTIFICATION; DRUG ISOLATION; DRUG SCREENING; DRUG SYNTHESIS; HIGHER PLANT; INFRARED SPECTROMETRY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; ORAL DRUG ADMINISTRATION; PRELIMINARY COMMUNICATION; PRIORITY JOURNAL; THIN LAYER CHROMATOGRAPHY; THROMBOCYTE AGGREGATION; ULTRAVIOLET SPECTROPHOTOMETRY;

EID: 0021749332     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja00338a049     Document Type: Article

References (23)

1. Block, E.; O'Connor, J. J. Am. Chem. Soc. 1974, 96, 3929–3944.
2. Lau, B. H. S.; Adetumbi, M. A.; Sachez, A. Nutr. Res. (N.Y.) 1983, 3, 119–128.
3. Bolton, S.; Null, G.; Troetel, W. M. Am. Pharm. 1982, NS22, 40–43.
4. Singer, M. “The Fanatic's Ecstatic Aromatic Guide to Onions, Garlic, Shallots and Leeks”; Prentice Hall: Englewood Cliffs, NJ, 1981.
5. Pros, J. S. “Virtudes Curativas del Ajo”; Editorial Sintes: Barcelona, 1975.
6. Harris, L. J. “The Book of Garlic”; Holt, Rinehart and Winston: New York, 1974.
7. Watanabe, T. “Garlic Therapy”; Japan Publications: Tokyo, 1974.
8. Binding, G. J. “About Garlic”; Thorsons Publishers: London, 1970; and references therein.
9. Cavallito, C. J.; Bailey, J. H. J. Am. Chem. Soc. 1944, 66, 1950–1951.
10. Cavallito, C. J.; Buck, J. S.; Suter, C. M. J. Am. Chem. Soc. 1944, 66, 1952–1954.
11. Barone, F. E. Mycologia 1977, 69, 793–825.
12. Bordia, A. Atherosclerosis (Shannon, Irel.) 1978, 30, 355–360.
13. Samson, R. R. Atherosclerosis (Shannon, Irel.) 1982, 44, 119–120.
14. Augusti, K. T.; Mathew, P. T. Experientia 1974, 30, 468–470.
15. Ariga, T.; Oshiba, S.; Tamada, T. Lancet 1981, 1, 150–151.
16. Apitz-Castro, R.; Cabrera, S.; Cruz, M. R.; Ledezma, E.; Jain, M. K. Thromb. Res. 1983, 32, 155–169.
17. Bock, H.; Mohmand, S.; Hirabayashi, T.; Semkow, A. Chem. Ber. 1982, 115, 1339–1348.
18. Vedejs, E.; Eberlein, T. H.; Varie, D. L. J. Am. Chem. Soc. 1982, 104, 1445–1447.
19. Bell, R.; Cottam, P. D.; Davies, J.; Jones, D. N.; Meanwell, N. A. Tetrahedron Lett. 1980, 21, 4379–4382.
20. Brodnitz, M. H.; Pascale, J. V.; Van Derslice, L. J. Agric. Food Chem. 1971, 19, 273–275.
21. Stoll, A.; Seebeck, E. Adv. Enzymol. Relat. Subj. Biochem. 1951, 11, 377–400.
22. Baldwin, J. E.; Lopez, R. G. Tetrahedron 1983, 39, 1487–1498.
23. Kice, J. L. Adv. Phys. Org. Chem. 1980, 77, 65–181.