2-Phenylindoles. relationship between structure, estrogen receptor affinity, and mammary tumor inhibiting activity in the rat

Journal of Medicinal Chemistry

Volumn 27, Issue 11, 1984, Pages 1439-1447

  Angerer, Erwin von ^a   Prekajac, Jelica ^a   Strohmeier, Josef ^a  

^a UNIVERSITY OF REGENSBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

2 PHENYLINDOLE DERIVATIVE; 7,12 DIMETHYLBENZ[A]ANTHRACENE; ESTRADIOL; ESTROGEN RECEPTOR; ESTRONE; HEXESTROL; NEW DRUG; RADIOISOTOPE; TAMOXIFEN; ZINDOXIFENE;

5 ACETOXY 2 (3 ACETOXYPHENYL) 1 ETHYL 3 METHYLINDOLE; 5 ACETOXY 2 (4 ACETOXYPHENYL) 3 METHYL 1 PROPYLINDOLE; 6 ACETOXY 2 (3 ACETOXYPHENYL) 1 ETHYL 3 METHYLINDOLE; 6 ACETOXY 2 (4 ACETOXYPHENYL) 1 ETHYL 3 METHYLINDOLE; 6 ACETOXY 2 (4 ACETOXYPHENYL) 1,3 DIETHYLINDOLE; 6 ACETOXY 2 (4 ACETOXYPHENYL) 1,3 DIMETHYLINDOLE; 6 ACETOXY 2 (4 ACETOXYPHENYL) 3 ETHYL 1 METHYLINDOLE; ANIMAL CELL; ANIMAL EXPERIMENT; BREAST; BREAST TUMOR; CANCER CHEMOTHERAPY; CATTLE; CHEMICAL CARCINOGENESIS; DOSE RESPONSE; DRUG ANALYSIS; DRUG ANTAGONISM; DRUG COMPARISON; DRUG EFFICACY; DRUG IDENTIFICATION; DRUG MECHANISM; DRUG RECEPTOR BINDING; DRUG RESPONSE; DRUG SCREENING; DRUG SYNTHESIS; ESTRADIOL H 3; FEMALE GENITAL SYSTEM; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; PHARMACOKINETICS; RAT; STRUCTURE ACTIVITY RELATION; SUBCUTANEOUS DRUG ADMINISTRATION; THERAPY;

ANIMAL; ANTINEOPLASTIC AGENTS; CATTLE; FEMALE; INDOLES; MAMMARY NEOPLASMS, EXPERIMENTAL; RATS; RATS, INBRED STRAINS; RECEPTORS, ESTROGEN; STRUCTURE-ACTIVITY RELATIONSHIP; SUPPORT, NON-U.S. GOV'T; UTERUS;

EID: 0021738560     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00377a011     Document Type: Article

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