Cysteine proteinases and metastasis

CANCER AND METASTASIS REVIEW

Volumn 3, Issue 3, 1984, Pages 249-263

  Sloane, Bonnie F ^a   Honn, Kenneth V ^a  

^a WAYNE STATE UNIVERSITY   (United States)

Author keywords

B16 melanoma; cathepsin B; cysteine proteinases; human tumors; invasion; metastasis

Indexed keywords

CATHEPSIN; CATHEPSIN B; CLOSTRIDIOPEPTIDASE A; CYSTEINE PROTEINASE; PROTEINASE;

ANIMAL; CELL CULTURE; CELL MEMBRANE; CELL MOTION; ENZYMOLOGY; HUMAN; LYSOSOME; METABOLISM; METASTASIS; NEOPLASM; PATHOLOGY; PATHOPHYSIOLOGY; REVIEW;

ANIMAL; CATHEPSIN B; CATHEPSINS; CELL MEMBRANE; CELL MOVEMENT; CELLS, CULTURED; CYSTEINE ENDOPEPTIDASES; ENDOPEPTIDASES; HUMAN; LYSOSOMES; MICROBIAL COLLAGENASE; NEOPLASM METASTASIS; NEOPLASMS; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0021728249     PISSN: 01677659     EISSN: 15737233     Source Type: Journal    
DOI: 10.1007/BF00048388     Document Type: Article

References (124)

1. Extracellular matrix destruction by invasive tumor cells
2. Proteolytic mechanisms of tissue destruction in tumor growth and metastasis
3. The role of proteinases in cellular invasiveness
4. Tumor invasion and the extracellular matrix
5. Tumor invasion and host extracellular matrix
6. Role of collagenases in tumor cell invasion
7. Inhibition of tumorigenesis in mouse skin by leupeptin, a protease inhibitor from Actinomycetes
8. Protease inhibitors suppress radiation-induced malignant transformation in vitro
9. Effects of protease inhibitors on radiation transformation in vitro
10. Conditions for inhibiting and enhancing effects of the protease inhibitor antipain on x-ray induced neoplastic transformation in hamster and mouse cells
11. Effects of protease inhibitors on growth of hamster tumor cells in culture
12. Selective inhibition of growth of transformed cells by protease inhibitors
13. Isolation of a cartilage factor that inhibits tumor neovascularization
14. Shark cartilage contains inhibitors of tumor angiogenesis
15. Proteolytic enzymes initiating cell division and escape from contact inhibition of growth
16. Overgrowth stimulating factor released from Rous sarcoma cells
17. The many forms and functions of cellular proteinases
18. Evolution of proteolytic enzymes
19. Homology of amino acid sequences of rat liver cathepsins B and H with that of papain
20. Amino acid sequence around the active site cysteine residue of calcium activated neutral protease (CANP)
21. Steady state kinetic evidence for an acyl-enzyme intermediate in reactions catalyzed by bovine spleen cathepsin B
22. The pH dependency of bovine spleen cathepsin B catalyzed transfer of N-benzyloxycarbonyl-L-lysine from p-nitrophenol to water and dipeptide nucleophiles. Comparisons with papain
23. Structures and functions of lysosomal thiol proteinases and their endogenous inhibitor
24. Characterization of a thiol proteinase secreted by malignant human breast tumors
25. Human cathepsin B1. Purification and some properties of the enzyme
26. Degradation of myofibrillar proteins by cathepsins B and D
27. Susceptibilities of various myofibrillar proteins to cathepsin B and morphological alteration of isolated myofibrils by this enzyme
28. Action of human liver cathepsin B on the oxidized insulin B chain
29. The specificity of cathepsin B. Hydrolysis of glucagon at the C-terminus by a peptidyldipeptidase mechanism
30. Degradation of fructose-1,6-biphosphate aldolase by cathepsin B. A further example of peptidyldipeptidase activity of this proteinase
31. Cathepsins B1 and D action on human cartilage proteoglycans
32. Cathepsin B1. A lysosomal enzyme that degrades native collagen
33. The action of cathepsin B and collagenolytic cathepsin in the degradation of collagen
34. Further studies on the activation of procollagenase, the latent precursor of bone collagenase. Effects of lysosomal cathepsin B, plasmin and kallikrein, and spontaneous activation
35. Cellular detachment by purified lysosomal cathepsin B
36. Human cathepsin H
37. Cathepsin L. A new proteinase from rat liver lysosomes
38. Action of rat liver cathepsin L on collagen and other substrates
39. Limited autolysis reduces the Ca2+ requirement of a smooth muscle Ca2+-activated protease
40. Evidence for two structurally different forms of skeletal muscle Ca2+-activated protease
41. Two distinct Ca2+ proteases (calpain I and calpain II) purified concurrently by the same method from rat kidney
42. Purification and characterization of two forms of Ca2+-activated neutral protease from calf brain
43. Calcium-dependent proteolysis in living cells
44. Stimulation of rat platelet adenylate cyclase by an endogenous calcium-dependent protease-like activity
45. Proteolysis of the epidermal growth factor receptor by endogenous calcium-activated neutral protease from rat liver
46. Proteolysis of vimentin and desmin by the Ca2+-activated proteinase specific for these intermediate filament proteins
47. Calcium-activated neutral protease: its degradative role in muscle cells
48. Cleavage of cytoskeletal proteins by two forms of Ca activated neutral proteases in human platelets
49. Purification of human platelet calcium-activated protease. Effect on platelet and endothelial function
50. Enzyme activity in invasive tumors of human breast and colon
51. On the in vitro release of cytoplasmic enzymes from ascites tumor cells as compared with strain L cells
52. The content of dipeptidases and acid proteinases in the ascitic fluid of mice with ascites tumors
53. Immunofluorescent studies on the occurrence of cathepsin B1 at tumor cell surfaces
54. Elevation of lysosomal enzymes in primary Lewis lung tumor correlated with the initiation of metastasis
55. Some mechanisms involved in cancer cell detachment by necrotic material
56. The histological distribution of proteinase and peptidase activity in solid mouse tumor transplants. A histochemical study on the enzymic characteristics of the different tumor cell types
57. Increase of lysosomal enzymes in skin cancer
58. Cathepsin B activity in B16 melanoma cells: a possible marker for metastatic potential
59. Proteolytic and metastatic activities of clones derived from a methylcholanthrene-induced murine fibrosarcoma
60. Comparative studies of mouse liver cathepsin B and an analogous tumor thiol proteinase
61. Purification and properties of a cathepsin B-like enzyme from human tumors: comparison with cathepsin B isolated from human liver and spleen (Abstract)
62. Lysosomal cathepsin B: correlation with metastatic potential
63. Association of cysteine proteinase activities with viable tumor cells isolated from rodent primary subcutaneous tumors (Abstract)
64. Tumor cysteine proteinases, platelet aggregation and metastasis
65. Heparan sulfate degradation correlates with tumor invasive and metastatic properties of B16 melanoma sublines
66. Enhanced metastatic potential of cloned low-metastatic Lewis lung carcinoma cells treated in vitro with dimethyl sulfoxide
67. Biochemical methods for predicting metastatic ability of prostatic cancer utilizing the Dunning R-3327 rat prostatic adenocarcinoma system as a model
68. Biochemical parameters correlated with tumor cell implantation
69. Tumor cell surfaces: some characteristics of neoplastic cells that determine states of transformation and malignancy
70. Alkaline phosphatase and acid arylamidase as marker enzymes for normal and transformed WI-38 cells
71. Localization and characterization of N-ethyl maleimide sensitive inhibitor(s) of thiol cathepsin activity from cultured Nil and polyoma virus-transformed Nil hamster cells
72. Lysosomal cathepsin B-like activity: mobilization in prereplicative and neoplastic epithelial cells
73. Synthesis of cathepsin B by cells derived from the HL60 promyelocytic leukemia cell line
74. Clonal drift of cell surface, melanogenic, and experimental metastatic properties of in vivo selected, brain meninges-colonizing murine B16 melanoma
75. Phenotypic drift and heterogeneity in response of metastatic mammary adenocarcinoma cell clones to Adriamycin, 5-fluoro-2′-deoxyuridine and methotrexate treatment in vitro
76. Quantitative and qualitative studies of chemical transformation of cloned C3H mouse embryo cells sensitive to postconfluence inhibition of cell division
77. Methods and models for studying tumor invasion
78. Lysosomal composition in cultured vascular smooth muscle cells: electron probe analysis
79. The pathogenesis of atherosclerosis
80. Subcellular fractionation and morphology of calf aortic smooth muscle cells. Studies on whole aorta, aortic explants, and subcultures grown under different conditions
81. Modulation of lysosomal enzyme levels in cultured cells. Effects of alterations in cell density, balanced growth, and endocytosis
82. Separation of cells from mouse solid tumors by centrifugal elutriation
83. Synchronization of mouse L-P59 cells by centrifugal elutriation separation
84. Isolation of quiescent cells from multicelluar tumor spheroids using centrifugal elutriation
85. Characterization of a murine ovarian reticulum cell sarcoma of histocytic origin
86. Collagenolytic activities in methylcholanthrene-induced fibrosarcomas in mice
87. Cysteine proteinases of lysosomes
88. Tumor cell-platelet aggregation: induced by cathepsin B-like proteinase and inhibited by prostacyclin
89. Involvement of a cathepsin B-like cysteine proteinase in platelet aggregation induced by tumor cells and their shed membrane vesicles
90. Histochemical localization of cathepsin B at the invasion front of the rabbit V2 carcinoma
91. A cysteine proteinase secreted from human breast tumours is immunologically related to cathepsin B
92. Differences in secretion of the proteinase cathepsin B at the edges of human breast carcinomas and fibroadenomas
93. Secretion of proteinases from malignant and nonmalignant human breast tissue
94. Increased cathepsin B activity in pancreatic juice from a patient with pancreatic cancer
95. Elevated serum cathepsin B1 and vaginal pathology after prenatal DES exposure
96. Elevated serum cathepsin B1-like activity in women with neoplastic disease
97. Detection of increased levels of cysteinyl proteinase activity in urine of gynecological cancer patients (Abstract)
98. Production of monoclonal antibodies against cathepsin B-like enzyme derived from urine of gynecologic cancer patients (Abstract)
99. Secretion of a thiol proteinase from mouse mammary carcinomas and its characterization
100. Lipoxygenase products as mediators of tumor cell lysosomal enzyme release: inhibition by nafazatrom
101. A latent thiol proteinase from ascitic fluid of patients with neoplasia
102. Extracellular cysteine proteinase and collagenase activities as a consequence of tumor-host interaction in the rabbit V2 carcinoma
103. Cathepsin B-like enzymes. Subcellular distribution and properties in neoplastic and control cells from human ectocervix
104. Proteolytic activities associated with plasma membrane preparations from tumour cells in enzootic bovine leukosis and from normal bovine lymphoid cells
105. In vitro mechanisms of platelet aggregation by purified plasma membrane vesicles shed by mouse 15091A tumor cells
106. Aggregation of platelets and cell membrane vesiculation by rat cells transformed in vitro by Rous sarcoma virus
107. Arrest and metastasis of blood-borne tumor cells are modified by fusion of plasma membrane vesicles from highly metastatic cells
108. Tumor cell proteinase visualization and quantification using a fluorescent transition-state analog probe
109. A trypsin-like neutral protease on Ehrlich ascites cell surfaces: its role in the activation of tumour-cell zymogen of collagenase
110. Inhibition of free and bound trypsin-like enzymes
111. Proteolysis by neutrophils. Relative importance of cell-substrate contacts and oxidative inactivation of proteinase inhibitors in vitro
112. Characterization of a latent cysteine proteinase from ascitic fluid as a high molecular weight form of cathepsin B
113. Latent collagenase from human polymorphonuclear leukocytes and activation to collagenase by removal of an inhibitor
114. Human cathepsin B1. Inhibition by α2-macroglobulin and other serum proteins
115. Human plasma α1- and α2-thiol proteinase inhibitors strongly inhibit Ca-activated neutral protease from muscle
116. Preventive role of protease inhibitors on lung metastasis of ascites hepatoma
117. Lysosomal enzyme inhibitors and antimetastatic activity in the mouse
118. Paradoxical effect of leupeptin in vivo on cathepsin B activity