Metabolism in vivo of furazolidone: Evidence for formation of an open-chain carboxylic acid and α-ketoglutaric acid from the nitrofuran in rats

Archives of Biochemistry and Biophysics

Volumn 234, Issue 1, 1984, Pages 112-116

  Tatsumi, Kiyoshi ^a   Nakabeppu, Hitoshi ^a   Takahashi, Yoshihiro ^a   Kitamura, Shigeyuki ^a  

^a HIROSHIMA UNIV SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

FURAZOLIDONE;

ANIMAL EXPERIMENT; DRUG METABOLISM; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT;

ADMINISTRATION, ORAL; ANIMAL; BIOTRANSFORMATION; CARBOXYLIC ACIDS; FURAZOLIDONE; KETOGLUTARIC ACIDS; MAGNETIC RESONANCE SPECTROSCOPY; MALE; RATS; RATS, INBRED STRAINS; SPECTRUM ANALYSIS, MASS;

EID: 0021720591     PISSN: 00039861     EISSN: 10960384     Source Type: Journal    
DOI: 10.1016/0003-9861(84)90330-8     Document Type: Article

References (9)

1. Isolation and identification of the metabolite of N-(5-nitro-2-furfurylidene)-3-amino-2-oxazolidone (furazolidone).