Biologic and biochemical effects of mitoxantrone

Seminars in Oncology

Volumn 11, Issue 3 SUPPL. 1, 1984, Pages 3-10

  Durr, Frederick E ^a  

^a WYETH RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; CYCLOPHOSPHAMIDE; CYTARABINE; DOXORUBICIN; FLUOROURACIL; METHOTREXATE; MITOXANTRONE; VINCRISTINE;

BLOOD AND HEMOPOIETIC SYSTEM; CANCER CHEMOTHERAPY; DRUG EFFICACY; DRUG TOXICITY; IN VITRO STUDY; INTOXICATION; LEUKEMIA CELL; MOUSE; NONHUMAN; THERAPY;

ANIMAL; ANTHRAQUINONES; ANTINEOPLASTIC AGENTS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CELL LINE; COLONIC NEOPLASMS; DNA REPLICATION; DRUG RESISTANCE; HUMAN; MICE; MITOXANTRONE; NEOPLASMS, EXPERIMENTAL; TRANSCRIPTION, GENETIC;

EID: 0021690087     PISSN: 00937754     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Antitumor agents I. 1,4-bis-(aminoalkylamino)-9,10-anthracenediones
2. Activity of a novel anthracenedione, 1,4-dihydroxy-5,8-bis((2-((2-hydroxyethyl)amino)-ethyl)-amino)-9,10-anthracenedione dihydrochloride, against experimental tumors in mice
3. Comparison of the antitumor activity of CL 232,315, a novel aminoanthraquinone, with standard anticancer agents
4. Molecular and biochemical pharmacology of mitoxantrone
5. CL 232,315 (NSC-301739) 1,4-dihydroxy-5,8-bis((2-((2-hydroxyethyl)amino)-ethyl)amino)-9-l0-anthracenedione dihydrochloride: A novel antitumor agent
6. Experimental antitumor activity of aminoanthraquinones
7. DNA-binding specificity and RNA polymerase inhibitory activity of bis (aminoalkyl) anthraquinones and bis (methylthio) vinylquinolinium iodides
8. Interactions of a new antitumor agent, 1,4-dihydroxy-5,8-bis((2-((2-hydroxyethyl)amino)ethyl)amino)-9,10-anthracenedione with nucleic acids
9. Comparison of the interaction of antineoplastic aminoanthraquinone analogs with DNA using competitive fluorescence polarization
10. The inhibitory effect of 1,4-dihydroxy-5,8-bis((2-((2-hydroxyethyl)-amin)ethyl)amino))-9,10-anthracendione dihydrochloride (CL 232,315; NSC-301739D) on dividing and nondividing cells in vitro
11. Action of dihydroxyanthraquinone on cell cycle progression and survival of a variety of cultured mammalian cells
12. Protein associated DNA single strand breaks and cytotoxicity of dihydroxyanthracenedione (DHAD); NSC-301739, in mouse L1210 leukemia cells
13. Studies on the development of resistance to mitoxantrone in human colon carcinoma cells in vitro
14. Uptake and retention of adriamycin and daunorubicin by sensitive and anthracyclineresistant sublines of P388 leukemia
15. Anthracycline antibiotic pharmacology and metabolism
16. Nuclear catalyzed antibiotic free radical formation
17. Differential effects of anthracycline drugs on rat heart and liver microsomal reduced nicotinamide adenine dinucleotide phosphate-dependent lipid peroxidation
18. Comparative cardiac oxygen radical metabolism by anthracycline antibiotics, mitoxantrone, bisantrene, 4′-(9-acridinylamino)-methanesulfonm-anisidide, and neocarzinostatin
19. Safety assessment of a new anticancer compound, mitoxantrone, in beagle dogs: Comparison with doxorubicin. II Histologic and ultrastructural pathology