Kinetic Studies on the Mechanism of the Penicillin Amidase-Catalysed Synthesis of Ampicillin and Benzylpenicillin

Hoppe-Seyler's Zeitschrift fur Physiologische Chemie

Volumn 365, Issue 2, 1984, Pages 1435-1444

  Kasche, Volker ^a   Haufler, Ursula ^a   ZöLlner, Roswitha ^a  

^a UNIVERSITY OF BREMEN   (Germany)

Author keywords

Ampicillin, acyl enzyme, semisynthetic penicillins, penicillin amidase, nucleophilic deacylation

Indexed keywords

6 AMINOPENICILLANIC ACID; AMPICILLIN; PENICILLIN AMIDASE; PENICILLIN G; PHENYLACETIC ACID;

DEXTRO PHENYLGLYCINE; DOSE RESPONSE; DRUG MECHANISM; DRUG RESPONSE; DRUG SYNTHESIS; NONHUMAN; PHARMACOKINETICS; PHENYLGLYCINE METHYL ESTER;

AMIDOHYDROLASES; AMPICILLIN; ESCHERICHIA COLI; ISOELECTRIC FOCUSING; KINETICS; OSMOLAR CONCENTRATION; PENICILLANIC ACID; PENICILLIN AMIDASE; PENICILLIN G; SUPPORT, NON-U.S. GOV'T;

EID: 0021672205     PISSN: 00184888     EISSN: 14374315     Source Type: Journal    
DOI: 10.1515/bchm2.1984.365.2.1435     Document Type: Article

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