Enteropathogenic escherichia coli of classic serotypes associated with infant diarrhea: Epidemiology and pathogenesis

Epidemiologic Reviews

Volumn 6, Issue 1, 1984, Pages 31-51

  Levine, Myron M ^a   Edelman, Robert ^b  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ANTIGEN; ENTEROTOXIN;

ADULT; ANIMAL; BIOSYNTHESIS; CLASSIFICATION; DISEASE CARRIER; DISEASE TRANSMISSION; ENTEROBACTER INFECTION; EPIDEMIC; ESCHERICHIA COLI; GENETICS; HUMAN; INFANT; INFANTILE DIARRHEA; INTESTINE MUCOSA; METABOLISM; MICROBIOLOGY; PATHOGENICITY; PATHOLOGY; PLASMID; REVIEW; SEROTYPING; DIARRHEA; DIGESTIVE SYSTEM; EPIDEMIOLOGY; ETIOLOGY;

ADULT; ANIMAL; ANTIGENS, BACTERIAL; DIARRHEA, INFANTILE; DISEASE OUTBREAKS; DISEASE RESERVOIRS; ENTEROTOXINS; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; HUMAN; INFANT; INTESTINAL MUCOSA; PLASMIDS; SEROTYPING;

EID: 0021645988     PISSN: 0193936X     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.epirev.a036274     Document Type: Article

References (144)

1. Levine MM, Kaper JB, Black RE, et al. New knowledge on pathogenesis of bacterial enteric infections as applied to vaccine development. Microbiol Rev 1983;47:510-50.
2. Edelman R, Levine MM. Acute diarrheal infections in infants. II. Bacterial and viral causes. Hosp Pract 1980;15:97-104.
3. Harris JR, Wachsmuth IK, Davis BR, et al. High-molecular-weight plasmid correlates with Escherichia coli enteroinvasiveness. Infect Immun 1982;37:1295-8.
4. Sansonetti PJ, Kopecko DJ, Formal SB. Involvement of a plasmid in the invasive ability of Shigella flexneri. Infect Immun 1982;35: 852-60.
5. Riley L, Remis RS, Helgerson SD, et al. Hemorrhagic colitis associated with a rare Escherichia coli serotype. N Engl J Med 1983; 308:681-5.
6. Wells JG, Davis BR, Wachsmuth IK, et al. Laboratory investigation of hemorrhagic colitis outbreaks associated with a rare Escherichia coli serotype. J Clin Microbiol 1983; 18:512-20.
7. O’Brien AD, Lively TA, Chen ME, et al. Escherichia coli 0157:H7 strains associated with hemorrhagic colitis in the United States produce a Shigella dysenteriae 1 (Shiga)-like cy- totoxin. Lancet 1983;1:1235-6.
8. Bray J. Isolation of antigenically homogeneous strains of Bact. coli neapolitanum from summer diarrhoea of infants. J Pathol Bacte- riol 1945;57:239-47.
9. Bray J, Beaven TED. Slide agglutination of Bad. coli var neapolitanum in summer diarrhea. J Pathol Bacteriol 1948;60:395-401.
10. Giles C, Sangster MB. An outbreak of infantile gastroenteritis in Aberdeen. J Hyg 1948; 46:1-9.
11. Giles C, Sangster G, Smith J. Epidemic gastroenteritis of infants in Aberdeen during 1947. Arch Dis Child 1949;24:45-53.
12. Taylor J, Powell BW, Wright J. Infantile diarrhea and vomiting: a clinical and bacteriological investigation. Br Med J 1949;2:117-41.
13. Kauffmann F, DuPont A. Escherichia strains from infantile epidemic gastroenteritis. Acta Pathol Microbiol Scand 1950;27:552-64.
14. 4. J Lab Clin Med 1952;32:122-8.
15. Hinton NA, MacGregor RR. A study of infections due to pathogenic serogroups of Escherichia coli. Can Med Assoc J 1958;79:359-64.
16. Neter E, Westphal O, Luderitz O, et al. Demonstration of antibodies against enteropatho- genic Escherichia coli in sera of children of various ages. Pediatrics 1955;16:801-7.
17. Kirby AC, Hall EG, Coackley W. Neonatal diarrhoea and vomiting: outbreaks in the same maternity unit. Lancet 1950;2:201-7.
18. Neter E, Shumway C. E. coli serotype D433: occurrence in intestinal and respiratory tracts. Cultural characteristics, pathogenicity, sensitivity to antibiotics. Proc Soc Exp Biol Med 1950;75:504-7.
19. 4, a coliform organism associated with infant diarrhea. Am J Hyg 1952;55:155-69.
20. 5, a coliform organism associated with infant diarrhea. Am J Hyg 1953;57:222-36.
21. 4 in the intestinal tract of adult volunteers in feeding experiments: intubation study with Miller-Abbott’s double lumen tube. Jpn J Med Sci Biol 1954;7:197-201.
22. 4 in the intestinal tract of adult volunteers and its relation to manifestation of coli enteritis. Jpn J Med Sci Biol 1954;7:655-61.
23. Wentworth FH, Brock DW, Stulberg CS, et al. Clinical, bacteriological and serological observations on two human volunteers following ingestion of Escherichia coli 0127:B8. Proc Soc Exp Biol Med 1956;91:586-8.
24. Sack RB, Hirschhorn N, Brownlee I, et al. Enterotoxigenic Escherichia coli associated with diarrheal disease in Apache children. N Engl J Med 1975;292:1041-5.
25. Gross RJ, Scotland SM, Rowe B. Enterotoxin testing of Escherichia coli causing epidemic infantile enteritis in the UK. Lancet 1976;1: 629-32.
26. Echevarria P, Blacklow NR, Sanford LB, et al. Enterotoxigenicity and invasive capacity of “enteropathogenic” serotypes of Escherichia coli. J Pediatr 1976;89:8-10.
27. Goldschmidt MC, DuPont HL. Enteropathogenic Escherichia coli: lack of correlation of serotype with pathogenicity. J Infect Dis 1976;133:153-6.
28. Sack RB. Serotyping of E. coli. Lancet 1976;1:1132.
29. Gurwith MJ, Wiseman DA, Chow P. Clinical and laboratory assessment of the pathogenicity of serotyped Escherichia coli. J Infect Dis 1977;135:736-43.
30. Gangarosa EU, Merson MH. Epidemiologic assessment of the relevance of the so-called enteropathogenic serogroups of Escherichia coli in diarrhea. N Engl J Med 1977;296:1210-13.
31. Kauffmann F. The serology of the coli group. J Immunol 1947;57:71-100.
32. Ewing WH. Isolation and identification of Escherichia coli serotypes associated with diarrheal diseases. Atlanta, GA: US Department of Health, Education and Welfare, Public Health Service, Communicable Disease Center, 1963.
33. Orskov I, Orskov F, Jann B, et al. Serology, chemistry and genetics of O and K antigens of Escherichia coli. Bacteriol Rev 1977;41:667-710.
34. Orskov F, Orskov I, Jann B, et al. Immuno- electrophoretic patterns of extracts from all Escherichia coli O and K antigen test strains: correlation with pathogenicity. Acta Pathol Microbiol Scand 1971;79(Section B):142-52.
35. Ewing WH, Davis BR, Montague TS. Studies on the occurrence of Escherichia coli serotypes associated with diarrheal disease. Atlanta, GA: US Department of Health, Education and Welfare, Public Health Service, Communicable Disease Center, 1963.
36. Taylor J. Host specificity and enteropathogen- icity of Escherichia coli. J Appl Bacteriol 1961;3:316-25.
37. Farmer JJ III, Davis BR, Cherry WB, et al. “Enteropathogenic serotypes” of Escherichia coli which really are not. J Pediatr 1977;90:1047-9.
38. Marker SC, Blazevic DJ. Enteropathogenic serotypes of E. coli. J Pediatr 1977;90:1037.
39. Goldschmidt R. Untersuchunger zur Atiologie det Durchfalserkrankungen des Sauglings. Jahrb Kinderheilk 1933;89:318-58.
40. Bray J. Bray’s discovery of pathogenic Esch. coli as a cause of infantile gastroenteritis. Arch Dis Child 1973;48:923-6.
41. Beavan TED. Society of medical officers of health discussion on infantile gastro-enteritis. Lancet 1944;1:568.
42. Smith J. Association of certain types (A and B) of Bact. coli with infantile gastroenteritis. J Hyg 1949;47:221-6.
43. Buttiaux R, Nicolle P, Le Minor L, et al. Études sur les E. coli de gastro-enterite infantile. Ann Inst Pasteur 1956;91:799-809.
44. Braun OH, Specht J. Beitrag zur Epidemiologie der infekiosen Colienteritis der Sauglinge. Z Kinderheilk 1955;76:197-207.
45. Olitzki AL. Investigations of infantile gastroenteritis in Jerusalem 1953-1956. Acta Med Orient 1956;15:137-44.
46. Mushin R, Lowson FM, Bishop RF. Bacteriological and epidemiological studies on coliform diarrhoea in children. Med J Aust 1960;2: 365-72.
47. Laurell G, Magnusson JH, Frisell E, et al. Epidemic infantile diarrhoea and vomiting. Acta Paediatr Scand 1951;40:302-37.
48. Joe LK, Sahab K, Hin PS. Escherichia coli type 0111:B4:H2 and type 055:B5:H~ in Djakarta: its epidemiological aspects. J Trop Pediatr 1958;4:20-7.
49. Orskov F. On the occurrence of E. coli belonging to O group 26 in cases of infantile diarrhea and white scours. Acta Pathol Microbiol Scand 1951;29:373-8.
50. Harris AH, Yankhauer A, Green DC, et al. Control of epidemic diarrhea of the newborn in hospital nurseries and pediatric wards. Ann NY Acad Sci 1956;66:118-28.
51. Ewing WH, Tatum HW, Davis BR. The occurrence of Escherichia coli serotypes associated with diarrheal disease in the United States. Public Health Lab 1957;15:118-38.
52. Smith J. The association of serological types of Bad. coli with infantile gastroenteritis. J Pathol Bacteriol 1953;65:503-11.
53. Ewing WH, Tanner KE, Tatum HW. A new serotype of Escherichia coli associated with infantile diarrhea. Public Health Rep 1955;70:107-14.
54. Taylor J, Charter R. Escherichia coli 0128 causing gastroenteritis of infants. J Clin Pathol 1955;8:276-81.
55. Stulberg CS, Zuelzer WW, Nolke AC, et al. Escherichia coli 0127:B8, a pathogenic strain causing infantile diarrhea. Am J Dis Child 1955;90:125-34.
56. Cooper ML, Walters EW, Keller HM. Detection of a new serotype of Escherichia coli, 0127:B8, associated with acute diarrhea in infants. J Bacteriol 1955;69:689-94.
57. Cooper ML, Walters EW, Keller HM, et al. Epidemic diarrhea among infants associated with the isolation of a new serotype of Escherichia coli: E. coli 0127:B8. Pediatrics 1955;16: 215-27.
58. Ewing WH. Enteropathogenic Escherichia coli serotypes. Ann NY Acad Sci 1956;66:61-70.
59. Payne AMM, Cook GT. A specific serological type of Bact. coli found in infants home in absence of epidemic diarrhoea. Br Med J 1950;2:192-5.
60. Cathie IAB, MacFarlane JCW. Incidence of Bact. coli O group 111 in sporadic infantile gastroenteritis. Br Med J 1951;2:1002-4.
61. Stevenson JS. Bact. coli D433 in cases of diarrhoea in adults. Br Med J 1950;2:195-6.
62. Stevenson JS. Further observations on the occurrence of Bact. coli D433 in adult faeces. Br Med J 1952;2:123-4.
63. Shanks RA, Studzinski LP. Bact. coli in infantile diarrhoea. Br Med J 1952;2:119-23.
64. Neter E. Enteritis due to enteropathogenic Escherichia coli. J Pediatr 1959;55:223-39.
65. Taylor J, Maltby MP, Payne JM. Factors influencing the response of ligated rabbit-gut segments to injected Escherichia coli. J Pathol Bacteriol 1958;76:491-9.
66. Taylor J, Wilkins MP, Payne JM. Relation of rabbit gut reaction to enteropathogenic Escherichia coli. Br J Exp Pathol 1961;42:43-52.
67. Thomson S, Watkins AG, Gray OP. Escherichia coli gastroenteritis. Arch Dis Child 1956;31:340-5.
68. Gamble DR, Rowson KEK. The incidence of pathogenic Escherichia coli in routine faecal specimens. Lancet 1957;2:619-21.
69. Hutchinson RI. Escherichia coli (O types 111, 55 and 26) and their association with infantile diarrhoea: a five-year study. J Hyg 1957;55: 27-44.
70. McCormack WM, Islam MdS, Fahimuddin Md, et al. A community study of inapparent cholera infections. Am J Epidemiol 1969;89:658-64.
71. Khan M, Shahidullah Md. Contrasting epidemiology of Shigellae dysenteriae and Shigellae flexneri, Dacca. Trans R Soc Trop Med Hyg 1980;74:528-33.
72. Aserkoff B, Schroeder SA, Brachman PS. Salmonellosis in the United States-a five year review. Am J Epidemiol 1970;92:13-24.
73. Shaughnessy HJ, Olsson RC, Bass K, et al. Experimental human bacillary dysentery. JAMA 1946;132:362-8.
74. Thomson S. The role of certain varieties of Bacterium coli in gastroenteritis of babies. J Hyg 1955;53:357-67.
75. Neter E, Westphal O, Luderitz O, et al. The bacterial hemagglutination test for the demonstration of antibodies to enterobacteriaceae. Ann NY Acad Sci 1956;66:141-56.
76. Young VM, Lindberg RB, Ortiz A, et al. Studies of infectious agents in feces of Puerto Rican children. Am J Trop Med Hyg 1962; 2:380-8.
77. Neter E, Zalewski NJ, Ferguson WN. Escherichia coli hemagglutinin response of adult volunteers to ingested E. coli O55 B5. Proc Soc Exp Biol Med 1953;82:215-19.
78. Taylor J. Infectious infantile enteritis, yesterday and today. Proc R Soc Med 1970; 63;1297-1301.
79. Olarte J, Ramos-Alvarez M. Epidemic diarrhea in premature infants: etiological significance of a newly recognized type of Escherichia coli (0142:K86(B):H6). Am J Dis Child 1965;109:436-8.
80. Hone R, Fitzpatrick S, Keane C, et al. Infantile enteritis in Dublin caused by Escherichia coli 0142. J Med Microbiol 1973;6:505-10.
81. Love WC, Gordon AM, Gross RJ, et al. Infantile gastroenteritis due to Escherichia coli 0142. Lancet 1972;2:355-7.
82. Kennedy DH, Walker GH, Fallon RJ, et al. An outbreak of infantile gastroenteritis due to E. coli 0142. J Clin Pathol 1973;26:731-7.
83. Jacobs SI, Holzel A, Wolman B, et al. Outbreak of infantile gastro-enteritis caused by Escherichia coli 0114. Arch Dis Child 1970;45: 656-63.
84. Pal SC, Rao CK, Keresclidze T, et al. An extensive community outbreak of enteropathogenic Escherichia coli 086:B7 gastroenteritis. Bull WHO 1969;41:851-8.
85. Severs D, Fardy P, Acres S, et al. Epidemic gastroenteritis in Newfoundland during 1963 asscoiated with E. coli 0111:B4. Can Med Assoc J 1966;94:373-8.
86. Boris M, Thomason BM, Hines VD, et al. A community epidemic of enteropathogenic Escherichia coli 0126:B16:NM gastroenteritis associated with asymptomatic respiratory infection. Pediatrics 1964;33:18-29.
87. Orskov F, Orskov I, Rees JA, et al. Two new E. coli O-antigens: 0141 and 0142 and two new coli K-antigens: K85 and K86. Acta Pathol Microbiol Scand 1960;48:48-50.
88. Boyer KM, Petersen NJ, Farzaneh I, et al. Anoutbreak of gastroenteritis due to E. coli 0142 in a neonatal nursery. J Pediatr 1975;86:919-27.
89. Goldhar J, Gutman R, Peri R. An outbreak caused by Escherichia coli 0126:K71:H5 in premature infants. Zentralbl Bakteriol Hyg I Abt Orig A 1981;250:470-7.
90. Costin ID, Voiculescu D, Gorcea V. An outbreak of food poisoning in adults associated with Escherichia coli serotype 86:B7:H34. Pathol Microbiol 1964;27:68-78.
91. Schroeder SA, Caldwell JR, Vernon TM, et al. A waterborne outbreak of gastroenteritis in adults associated with Escherichia coli. Lancet 1968;1:737-40.
92. French GL. Enteropathogenic E. coli. Lancet 1976;1:1411-12.
93. Levine MM, Bergquist EJ, Nalin DR, et al. Escherichia coli strains that cause diarrhoea but do not produce heat-labile or heat-stable enterotoxins and are non-invasive. Lancet 1978;1:1119-22.
94. Polotsky YE, Dragunskaya EM, Seliverstova VG, et al. Pathogenic effect of enterotoxigenic Escherichia coli and Escherichia coli causing infantile diarrhoea. Acta Micrbiol Acad Sci Hung 1977;24:221-36.
95. Moon HW, Whipp SC, Argenzio RA, et al. Attaching and effacing activities of rabbit and human enteropathogenic Escherichia coli in pig and rabbit intestines. Infect Immun 1983;41:1340-51.
96. Rothbaum R, McAdams J, Giannella R, et al. A clinicopathologic study of enterocyte-ad- herent Escherichia coli: a cause of protracted diarrhea in infants. Gastroenterology 1982;83:441-54.
97. Ulshen MH, Rollo JL. Pathogenesis of Escherichia coli gastroenteritis in man — another mechanism. N Engl J Med 1980;302:99-101.
98. Cravioto A, Gross RJ, Scotland SM, et al. An adhesive factor found in strains of Escherichia coli belonging to the traditional infantile enteropathogenic serotypes. Curr Microbiol 1979;3:95-9.
99. Trabulsi L. Quoted by Edelman R, Levine MM. Summary of a workshop on enteropathogenic Escherichia coli. J Infect Dis 1983;147: 1108-18.
100. Baldini MM, Kaper JB, Levine MM, et al. Plasmid-mediated adhesion in enteropathogenic Escherichia coli. J Pediatr Gastroenterol Nutr 1983;2:534-8.
101. Clausen CR, Christie DL. Chronic diarrhea in infants caused by adherent enteropathogenic Escherichia coli. J Pediatr 1982;100:358-61.
102. Drucker MM, Polliach A, Yeivin R, et al. Im- munofluorescent demonstration of enteropathogenic Escherichia coli in tissues of infants dying with enteritis. Pediatrics 1970;46:855-64.
103. McNeish AS, Turner P, Fleming J, et al. Mucosal adherence of human enteropathogenic Escherichia coli. Lancet 1975;2:946-8.
104. Williams PH, Sedgwick MI, Evans N, et al. Adherence of an enteropathogenic strain of Escherichia coli to human intestinal mucosa is mediated by a colicinogenic conjugative plasmid. Infect Immun 1978;22:393-402.
105. Nalin D. Quoted by Edelman R, Levine MM. Summary of a workshop on enteropathogenic Escherichia coli. J Infect Dis 1983;147: 1108-18.
106. Klipstein FA, Rowe B, Engert RF, et al. En- terotoxigenicity of enteropathogenic serotypes of Escherichia coli isolated from infants with epidemic diarrhea. Infect Immun 1978;21: 171-8.
107. O’Brien AD, LaVeck GD, Thompson MR, et al. Production of Shigella dysenteriae type 1-like cytotoxin by Escherichia coli. J Infect Dis 1982;146:763-9.
108. Konawalchuk J, Speirs JI, Stavric S. Vero response to a cytotoxin of Escherichia coli. Infect Immun 1977;18:775-9.
109. O’Brien AD, Chen ME, Wells JG, et al. Epidemiology of Shigella dysenteriae 1-like toxin production by Escherichia coli. In: Pierce N, Kuwahara S, eds. Advances in cholera and related diarrheas. Vol 2. Tokyo: KTK Scientific Publishers/Martinus Nijhoff, 1984 (in press).
110. Graber CD, Dunlop SG. Incidence of serologic types of Escherichia coli associated with infantile diarrhea among pediatric patients in the Denver area. J Lab Clin Med 1954;44:416-21.
111. Cooper ML, Keller HM, Walters EW. Comparative frequency of detection of enteropathogenic E. coli, Salmonella, and Shigella in rectal swab cultures from infants and young children. Pediatrics 1957;19:411-23.
112. Ramos-Alvarez, Sabin AB. Enteropathogenic viruses and bacteria. JAMA 1958;167:147-56.
113. Joe LK, Sahab K, Siok Yauw G-O, et al. Diarrhea among infants and children in Djakarta, Indonesia, with special reference to pathogenic Escherichia coli. Am J Trop Med Hyg 1960;9:626-32.
114. Wegman ME. The clinical significance of bacteria in the coliform, paracolon, pseudomonas, and similar groups. Am J Trop Med Hyg 1955;4:731-8.
115. Koomhoff HJ, Richardson NJ, Politzer WM, et al. A study of summer diarrhoea in white children in Johannesburg. S Afr Med J 1964; 38:821-6.
116. Guardiola-Rotger A, de Gonzalez EF, Kauder E, et al. Studies on diarrheal diseases. J Pediatr 1964;65:81-91.
117. Ramos-Alvarez M, Olarte J. Diarrheal disease of children: the occurrence of enteropathogenic viruses and bacteria. Am J Dis Child 1964;107:218-31.
118. Gaines S, Achavasmith Y, Thareesawat M, et al. Type and distribution of enteropathogenic Escherichia coli in Bangkok, Thailand. Am J Hyg 1964;80:388-94.
119. Yow MD, Melnick JL, Phillips CA, et al. An etiologie investigation of infantile diarrhea in Houston during 1962 and 1963. Am J Epidemiol 1966;83:255-61.
120. Ingram VG, Rights FL, Khan HA, et al. Diarrhea in children of West Pakistan: occurrence of bacterial and parasitic agents. Am J Trop Med Hyg 1966;15:743-50.
121. Moore HA, de la Cruz E, Vargas-Mendez O, et al. Diarrheal disease studies in Cost Rica. H. The prevalence of certain enteric organisms and their relationship to diarrhea. Am J Public Health 1966;56:442-51.
122. Moffet HL, Shulenberger HK, Burkholder ER. Epidemiology and etiology of severe infantile diarrhea. J Pediatr 1968;72:1-14.
123. Kourany M, Vasquez MA. Enteropathogenic bacteria associated with diarrhea among infants in Panama. Am J Trop Med Hyg 1969;18:930-5.
124. Yow MD, Melnick JL, Blattner RJ, et al. The association of viruses and bacteria with infantile diarrhea. Am J Epidemiol 1970;92:33-9.
125. Freiman I, Hartman E, Kassel H, et al. A microbiological study of gastro-enteritis in black infants. S Afr Med J 1977;52:261-5.
126. Sanyal SC, Sen PC, Tiwari IC, et al. Microbial agents in stools of infants and young children with and without acute diarrhoeal disease. J Trop Med Hyg 1977;80:2-8.
127. Maiya PP, Pereira SM, Mathan M, et al. Aetiology of acute gastroenteritis in infancy and early childhood in southern India. Arch Dis Child 1977;52:482-5.
128. Gurwith M, Hinde D, Gross R, et al. A prospective study of enteropathogenic Escherichia coli in endemic diarrheal disease. J Infect Dis 1978;137:292-7.
129. Abraham AA, Cahill KM, Davies J, et al. Studies on infantile diarrhea in Cairo, Egypt. Trop Pediatr Environ Child Health 1978; 24:187-94.
130. Koomhoff HJ, Robins-Browne RM, Richardson NJ, et al. Etiology of infantile enteritis in South Africa. Isr J Med Sci 1979;15:341-7.
131. Robins-Browne RM, Still CS, Miliotis MD, et al. Summer diarrhoea in African infants and children. Arch Dis Child 1980;55:923-8.
132. Weindling AM, Walter-Smith JA, Bind R. Micro-organisms in outpatient infantile gastroenteritis. Arch Dis Child 1980;55:185-8.
133. Toledo RF, Alvariza M do CB, Murahovschi J, et al. Enteropathogenic Escherichia coli serotypes and endemic diarrhea in infants. Infect Immun 1983;39:586-9.
134. Gronroos JA. Investigations on certain Escherichia coli sero-types: with special reference to infantile diarrhoea. Ann Med Exp Biol Fenn 1954;32(Suppl 4):1-71.
135. Donta ST, Wallace RB, Whipp SC, et al. Enterotoxigenic Escherichia coli and diarrheal disease in Mexican children. J Infect Dis 1977;155:482-5.
136. Maki M, Vesikari T, Gronroos P. Enterotoxigenic and invasive Escherichia coli as causes of childhood diarrhoea in Finland. Acta Pae- diatr Scand 1980;69:219-24.
137. Magalhaes M, Andrade M, Carvalho AE. Pathogenic Escherichia coli associated with infantile diarrhea. Rev Microbiol (S. Paulo) 1981;12:39-41.
138. Persson BL, Thoren A, Tufvesson B, et al. Diarrhoea in Swedish infants: aetiology and clinical appearance. Acta Paediatr Scand 1982;71:909-13.
139. Thoren A. The role of enteropathogenic E. coli in infantile diarrhoea: aspects on bacteriology, epidemiology and therapy. Scand J Infect Dis 1983;(Suppl 37):1-51.
140. Thomson S. Is infantile gastro-enteritis fundamentally a milk-borne infection. J Hyg 1956;54:311-14.
141. Cooper ML, Keller HM, Walters EW, et al. Isolation of enteropathogenic Escherichia coli from mothers and newborn infants. Am J Dis Child 1959;97:255-66.
142. Rogers KB, Koegler SJ. Inter-hospital crossinfection of epidemic infantile gastro-enteritis associated with type strains of Bacterium coli. J Hyg 1951;42:152-61.
143. Rogers KB. The spread of infantile gastro-enteritis in a cubicled ward. J Hyg 1951;49: 140-51.
144. Belnap WD, O’Donnell JJ. Epidemic gastroenteritis due to Escherichia coli O-lll: a review of the literature with the epidemiology, bacteriology and clinical findings of a large outbreak. J Pediatr 1955;47:178-93.