26,26,26,27,27,27-Hexafluoro-1,25-dihydroxyvitamin D3: A highly potent, long-lasting analog of 1,25-dihydroxyvitamin D3

Archives of Biochemistry and Biophysics

Volumn 229, Issue 1, 1984, Pages 348-354

  Tanaka, Yoko ^a   DeLuca, Hector F ^a   Kobayashi, Yoshiro ^b   Ikekawa, Nobuo ^c  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

^c TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CALCITRIOL; CALCIUM; FALECALCITRIOL; NEW DRUG; RADIOISOTOPE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; BLOOD AND HEMOPOIETIC SYSTEM; BONE; BONE MINERALIZATION; CALCIFEDIOL H 3; CALCITRIOL H 3; CHICKEN; DOSE RESPONSE; DRUG COMPARISON; DRUG EFFICACY; DRUG MECHANISM; DRUG PROTEIN BINDING; DRUG RECEPTOR BINDING; DRUG RESPONSE; NONHUMAN; ORAL DRUG ADMINISTRATION; PHARMACOKINETICS; PHOSPHATE BLOOD LEVEL; RAT; RICKETS; SMALL INTESTINE; SUBCUTANEOUS DRUG ADMINISTRATION; THERAPY;

ANIMAL; BIOLOGICAL TRANSPORT; BONE AND BONES; CALCITRIOL; CALCIUM; CARRIER PROTEINS; COMPARATIVE STUDY; DUODENUM; KINETICS; MALE; MINERALS; PHOSPHORUS; RATS; RECEPTORS, CALCITRIOL; RECEPTORS, STEROID; RICKETS; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.; VITAMIN D-BINDING PROTEIN;

EID: 0021347866     PISSN: 00039861     EISSN: 10960384     Source Type: Journal    
DOI: 10.1016/0003-9861(84)90161-9     Document Type: Article

References (24)

1. VITAMIN D METABOLISM
2. Synthesis of 24,24-difluoro- and 24ξ-fluoro-25-hydroxyvitamin D3
3. Synthesis of 26,26,26,27,27,27-hexafluoro-25-hydroxyvitamin D3
4. 25-Hydroxy-26,26,26,27,27,27-hexafluorovitamin D3: Biological activity in the rat