On the Possible Mechanism of Phenylacetate Neurotoxicity: Inhibition of Choline Acetyltransferase by Phenylacetyl‐CoA

Journal of Neurochemistry

Volumn 42, Issue 5, 1984, Pages 1499-1501

  Potempska, Anna ^a   Loo, Yen H ^a   Wisniewski, Henry M ^a  

^a NEW YORK STATE INSTITUTE FOR BASIC RESEARCH IN DEVELOPMENTAL DISABILITIES   (United States)

Author keywords

Acetyl CoA; ChATinhibition; Phenylacetate neurotoxicity; Phenylacetyl CoA

Indexed keywords

ACETYL COENZYME A SYNTHETASE; CHOLINE ACETYLTRANSFERASE; PHENYLACETIC ACID; RADIOISOTOPE;

CHOLINE H 3; DRUG MECHANISM; ENZYME INHIBITION; HUMAN; HUMAN CELL; INTOXICATION; NERVOUS SYSTEM; NEUROTOXICITY; PHENYLACETYL COENZYME A; PHENYLBUTYRIC ACID;

ACETATE-COA LIGASE; ACETYL COENZYME A; CHOLINE O-ACETYLTRANSFERASE; FEMALE; HUMAN; KINETICS; NEUROTOXINS; PHENYLACETATES; PHENYLKETONURIAS; PLACENTA; PREGNANCY; SACCHAROMYCES CEREVISIAE; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0021325438     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.1984.tb02819.x     Document Type: Article

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