Preferential induction of polyclonal IgA secretion by murine peyer’s patch dendritic cell-T cell mixtures

Journal of Experimental Medicine

Volumn 160, Issue 3, 1984, Pages 941-946

  Spalding, David M ^a   Williamson, Shane I ^a   Koopman, William J ^a   McGhee, Jerry R ^b  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b BIRMINGHAM VA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN A;

ANIMAL EXPERIMENT; DIGESTIVE SYSTEM; ENDOCRINE SYSTEM; IMMUNOREGULATION; LANGERHANS CELL; LYMPHATIC SYSTEM; MOUSE; NONHUMAN; PEYER PATCH; SPLEEN; T LYMPHOCYTE;

ANIMAL; B-LYMPHOCYTES; CELL COUNT; CLONE CELLS; IMMUNOGLOBULIN A; IMMUNOGLOBULIN M; LYMPHOCYTE ACTIVATION; LYMPHOCYTE COOPERATION; LYMPHOID TISSUE; MICE; MICE, INBRED C3H; MITOGENS; PEYER'S PATCHES; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.; T-LYMPHOCYTES;

EID: 0021269306     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.160.3.941     Document Type: Article

References (9)

1. Kiyono, H., J. R. McGhee, M.J. Wannemuehler, M. V. Frangakis, D. M. Spalding, S. M. Michalek, and W. J. Koopman. 1982. In vitro immune responses to a T cell-dependent antigen by cultures of disassociated murine Peyer’s patch. Proc. Natl. Acad. Sci. USA. 79: 596.
2. Kearney, J. F., and A. R. Lawton. 1975. B lymphocyte differentiation induced by lipopolysaccharide. I. Generation of cells synthesizing four major immunoglobulin classes. J. Immunol. 115: 671.
3. Elson, C. O., J. A. Heck, and W. Strober. 1979. T cell regulation of murine IgA synthesis. J. Exp. Med. 149: 632.
4. Kawanishi, H., L. E. Saltzman, and W. Strober. 1982. Characteristics and regulatory function of murine Con A-induced, cloned T cells obtained from Peyer’s patches and spleen. J. Immunol. 129: 475.
5. Frangakis, M. V., W.J. Koopman, H. Kiyono, S. M. Michalek, and J. R. McGhee. 1982. An enzymatic method for preparation of dissociated murine Peyer’s patch cells enriched for macrophages. J. Immunol. Methods. 48: 33.
6. Spalding, D. M., W.J. Koopman, J. H. Eldridge, J. R. McGhee, and R. M. Steinman. 1983. Accessory cells in murine Peyer’s patch. I. Identification and enrichment of a functional dendritic cell. J. Exp. Med. 157: 1646.
7. Wysocki, L. J., and V. L. Sato. 1978. "Panning" for lymphocytes: a new method of cell selection. Proc. Natl Acad. Sci. USA. 75: 2844.
8. Inaba, K., A. Granelli-Piperno, and R. Steinman. 1983. Dendritic cells induce T lymphocytes to release B cell-stimulating factors by an interleukin 2-dependent mechanism. J. Exp. Med. 158: 2040.
9. Mayer, L., S. M. Fu, and H. G. Kunkel. 1982. Human T cell hybridomas secreting factors for IgA-specific help, polyclonal B cell activation, and B cell proliferation. J. Exp. Med. 156: 1860.