Probes for Narcotic Receptor Mediated Phenomena. 6.1 Synthesis of (±)-(1α,4aα,9aβ)-1,3,4,9a-Tetrahydro-2-Methyl-2H-1,4a-Propanobenzofuro[2,3-c]Pyridin-8-ol, an Oxide-Bridged 5-(3-Hydroxyphenyl)Morphan

Journal of Organic Chemistry

Volumn 49, Issue 13, 1984, Pages 2508-2510

  Burke, Terrence R ^a   Jacobson, Arthur E ^a   Rice, Kenner C ^a   Silverton, J V ^b  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NEW DRUG;

1,3,4,9A TETRAHYDRO 2 METHYL 2H 1,4A PROPANOBENZOFURO[2,3 C]PYRIDIN 8 OL; DRUG ANALYSIS; DRUG IDENTIFICATION; DRUG STRUCTURE; DRUG SYNTHESIS; MASS SPECTROMETRY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRELIMINARY COMMUNICATION; THEORETICAL STUDY;

EID: 0021248596     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo00187a045     Document Type: Article

References (9)

1. Jacobson, A. E.; Bajwa, B. S.; Streaty; R. A.; Klee, W. A.; Rice, K. C. Life Sci. 1983, 33 (Suppl. I), 159.
2. May, E. L.; Murphy, J. G. J. Org. Chem. 1954, 19, 618. profs.
3. Burke, T. R., Jr.; Jacobson, A. E.; Rice, K. C.; Silverton, J. V. J. Org. Chem. 1984, 49, 1051.
4. Burke, T. R., Jr.; Jacobson, A. E.; Rice, K. C.; Weismann, B. A.; Silverton, J. V. Prob. Drug Depend., in press.
5. Schultz, A. G.; Motyka, L. A. In “Organic Photochemistry”; Padwa, A., ed.; Marcel Dekker: New York, 1983; Vol. 6, p 1.
6. Rice, K. C. J. Med. Chem. 1977, 20, 164.
7. Main, P.; Hull, S. E.; Lessinger, L.; Germain, G.; DeClercq, J. P.; Woolfson, M. M. MULTAN78, a system of computer programs for the solution of crystal structures from X-ray diffraction data; Universities of York and Louvain, 1978.
8. Stewart, J. M.; Kruger, G. J.; Ammon, H. L.; Dickinson, C.; Hall, S. R. XRAY72, Tech. Report TR-192, Computer Center, The University of Maryland, College Park, MD, 1972.
9. Johnson, C. K. ORTEP. Report ORNL-3794. Oak Ridge National Laboratory, Oak Ridge, TN, 1965.