Lipofuscin accumulation resulting from senescence and vitamin E deficiency: Spectral properties and tissue distribution

Mechanisms of Ageing and Development

Volumn 25, Issue 1-2, 1984, Pages 149-159

  Katz, Martin L ^a   Robinson Jr , W Gerald ^a   Herrmann, Roland K ^a   Groome, Anne B ^a   Bieri, John G ^a  

^a NATIONAL EYE INSTITUTE   (United States)

Author keywords

Aging; Fluorescence spectra; Lipofuscin; Retinal pigment epithelium; Vitamin E deficiency

Indexed keywords

ALPHA TOCOPHEROL; LIPOFUSCIN;

AGE; ANIMAL CELL; ANIMAL EXPERIMENT; CONGENITAL DISORDER; CYTOLOGY; DIAGNOSIS; METHODOLOGY; NONHUMAN; PIGMENT EPITHELIUM; RAT; SHORT SURVEY; VISUAL SYSTEM;

AGING; ANIMALS; CHOROID; DUODENUM; FEMALE; LIPOFUSCIN; MICROSCOPY, FLUORESCENCE; OLIVARY NUCLEUS; PIGMENT EPITHELIUM OF EYE; PIGMENTS, BIOLOGICAL; RATS; RATS, INBRED STRAINS; SCLERA; SPINAL CORD; UTERUS; VITAMIN E DEFICIENCY;

EID: 0021242471     PISSN: 00476374     EISSN: None     Source Type: Journal    
DOI: 10.1016/0047-6374(84)90137-4     Document Type: Article

References (19)

1. Cellular features, regional accumulation, and prospects of modification of age pigments in mammals
2. Effect of antioxidants and nutrients on lipid peroxidation fluorescence products and aging parameters in the mouse
3. Lipid peroxidation and fluorescent molecular damage to membranes
4. Lipid peroxidation, cross-linking reactions, and aging
5. Lipid pigments in relation to aging and dietary factors (lipofuscins)
6. Fluorescent pigment accumulation in retinal pigment epithlium of antioxidant deficient rats
7. Vitamin E deficiency and the retina: photoreceptor and pigment epithelial changes
8. Lipofuscin in vitamin E deficiency and the possible role of retinol
9. Simultaneous determination of α-tocopheral and retinol in plasma or red cells by high pressure liquid chromatography
10. Effect of dietary vitamin E on expiration of pentane and ethane by the rat
11. Properties of neuronal lipofuscin pigment in mice
12. Lipofuscin: resolution of discrepant fluorescence data
13. Procedures for the isolation of two distinct lipopigments from human brain: lipofuscin and ceroid
14. Studies on the chemical nature of lipofuscin (age pigment) isolated from normal human brain
15. Chemical characterization of age pigments
16. Isolierung und Eigenschaften von Lipofuscin aus Herzgewebe des Menschen
17. The roles of vitamin E and unsaturated fatty acids in the visual process