The neurobiology of vascular head pain

Annals of Neurology

Volumn 16, Issue 2, 1984, Pages 157-168

  Moskowitz, Michael A ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NEUROTRANSMITTER; SUBSTANCE P;

BRAIN BLOOD VESSEL; CENTRAL NERVOUS SYSTEM; CEREBROSPINAL FLUID; ETIOLOGY; HUMAN; MIGRAINE; PERIPHERAL VASCULAR SYSTEM; TRIGEMINUS GANGLION;

AFFERENT PATHWAYS; ANIMAL; ARTERITIS; BLOOD-BRAIN BARRIER; CAPILLARY PERMEABILITY; CEREBRAL ARTERIES; HUMAN; MIGRAINE; NERVE FIBERS; NEUROTRANSMITTERS; NOCICEPTORS; SPREADING CORTICAL DEPRESSION; SUBSTANCE P; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TRIGEMINAL GANGLION; TRIGEMINAL NERVE; VASCULAR HEADACHES;

EID: 0021183491     PISSN: 03645134     EISSN: 15318249     Source Type: Journal    
DOI: 10.1002/ana.410160202     Document Type: Article

References (154)

1. Human and rabbit platelets form platelet‐activating factor in response to calcium ionophore
2. Peptidergic (substance P) nerves in the genito‐urinary tract
3. Flunarizine, a calcium channel blocker: a new prophylactic drug in migraine
4. Cluster headache: ultrastructural aspects and pathogenetic mechanisms
5. Migraine, headache, and related conditions: panel 7
6. Headache in cerebral embolic disease
7. Bradykinin stimulates phospholipid methylation, calcium influx, prostaglandin formation, and cAMP accumulation in human fibroblasts
8. Endogenous pain control mechanisms: review and hypothesis
9. Substance P releases 3H‐arachidonic acid from vascular endothelial cells in culture
10. Enhancement of phagocytosis: a newly found activity of substance P residing in its N‐terminal tetrapeptide sequence
11. Hormone‐induced enlargement of receptive fields in trigeminal mechanoreceptive neurons. II. Possible mechanisms
12. Release of adenosine from ischemic brain: effect on cerebrovascular resistance and incorporation into cerebral adenine nucleotides
13. Substance P: release on trigeminal nerve stimulation, effects in the eye
14. Axonal transport of substance P in the vagus and sciatic nerves of the guinea pig
15. Substance P in trigeminal nerve endings: occurrence and release
16. Vasodilator axon reflexes
17. Neuropeptides in sensory neurons
18. Pathophysiology of migraine: a new hypothesis
19. Sympathetic innervation of vascular smooth muscle in normal and hypertensive animals: Symposium on Hypertensive Mechanisms
20. The effects of sensory denervation on the responses of the rabbit eye to prostaglandin E1, bradykinin and substance P
21. Some observations of the fifth and seventh cranial nerves
22. Endothelial cells and relaxation of vascular smooth muscle cells: possible relevane to lipoxygenases and their significance in vascular diseases
23. Isolation of a sialogogic peptide from bovine hypothalamic tissue and its characterization as substance P
24. Amino acid sequence of substance P
25. A humoral agent implicated in vascular headaches of the migraine type
26. Role of endothelial cells in relaxation of isolated arteries by bradykinin
27. Experimental studies on headache: observations on headache produced by histamine
28. The regional distribution of somatostatin, substance P, and neurotensin in human brain
29. Distribution of enteric neurons showing immunoreactivity for substance P in the guinea‐pig ileum
30. The dog common carotid artery: a sensitive bioassay for studying vasodilator effects of substance P and of kinins
31. Minireview: smooth muscle pharmacology of substance P
32. The central and peripheral ends of the substance P–containing sensory neurones in the rat trigeminal system
33. A method of total extirpation of the gasserian ganglion for trigeminal neuralgia
34. Surgery of the head
35. Coexistence of cholecystokinin—and substance P–like peptides in neurons of the dorsal root ganglia of the rat
36. Flunarizine, a calcium channel blocker, in the prophylactic treatment of migraine
37. Substance P in the cerebral vasculature: depletion by capsaicin suggests a sensory role
38. The vascular responses of the eye
39. Neurotransmitters decrease the calcium conductance activated by depolarization of embryonic chick sensory neurones
40. Aqueous flow determination in the rabbit by means of a minimal eye trauma
41. 7,9)–substance P of the cerebrovascular dilatation induced by substance P
42. Immunohistochemical localization and effect upon cat pial arteries in vitro and in situ
43. Feline cerebral veins and arteries: comparison of autonomic innervation and vasomotor responses
44. Immunohistochemical localization and dilatatory effect of substance P on human cerebral vessels
45. Enhancement of the permeability‐increasing effect of bradykinin and substance P by a peptide derived from fibrinogen
46. An identified depressor substance in certain tissue extracts
47. The mechanism of headache
48. The effects of substance P on histamine and 5‐hydroxytryptamine release in the rat
49. Clinical syndromes in cerebral arterial occlusion
50. Cerebral circulation: the reaction of the pial arteries to a fall of blood pressure
51. Cerebral circulation. II. Reaction of pial arteries to increase in blood pressure
52. The requirement for endothelial cells in the relaxation of arteries by acetylcholine and some other vasodilators
53. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine
54. Substance P–like immunoreactivity in nerves associated with the vascular system of guinea‐pigs
55. Decrease of substance P in primary afferent neurons and impairment of neurogenic plasma extravasation by capsaicin
56. Left‐handedness: association with immune disease, migraine, and developmental learning disorder
57. Herpes zoster ophthalmicus and delayed contralateral hemiparesis: relationship of the syndrome to central nervous system granulomatous angiitis
58. 5‐Hydroxytryptamine, bradyskinin an histamine as mediators of inflammatory hyperesthesia
59. Lesions of the central nervous system in herpes zoster
60. The nature of the endothelium‐derived vascular relaxant factor
61. Flare and itch induced by SP in human skin
62. The role of tyramine in the aetiology of migraine, and related studies on the cerebral and extracerebral circulations
63. Brain extracellular space during spreading depression and ischemia
64. + during spreading depression
65. Extracellular ion concentrations during spreading depression and ischemia in the rat brain cortex
66. Alcohol injection of the gasserian ganglion for migrainous neuralgia
67. Surgical treatment of intractable unilateral cephalgia
68. Immunoreactive substance P in rat blister fluid following sciatic nerve stimulation
69. Immunoreactive substance P in rat blisters
70. Effects of substance P on functionally identified units in cat spinal cord
71. Substance P in spinal sensory and autonomic pathways
72. Interactions of arachidonate products with other pain mediators
73. Dorsal root vasodilation in cat skeletal muscle
74. Experimental immunohistochemical studies on the localization and distribution of substance P in cat primary sensory neurons
75. Localization in the central nervous system and in some primary sensory neurons
76. A substance P antagonist, (D‐Pro2, D‐Trp7,9) SP, inhibits inflammatory responses in the rabbit eye
77. Chemosensitive pain fibres and inflammation
78. Desensitization with capsaicin and related acrylamides as a tool for studying the function of pain receptors
79. Direct evidence for neurogenic inflammation and its prevention by denervation and by pretreatment with capsaicin
80. The role of sensory nerve endings in neurogenic inflammation induced in human skin and in the eye and paw of the rat
81. Opiate analgesics inhibit substance P release from rat trigeminal nucleus
82. Capsaicin‐induced depletion of substance P from primary sensory neurons
83. Release of histamine from mast cells by vasoactive peptides
84. Substance P and noncholinergic excitatory synaptic transmission in guinea pig sympathetic ganglia
85. Headache provocation by continuous intravenous infusion of histamine: clinical results and receptor mechanisms
86. Headache
87. Patterns of cerebral integration indicated by the scotomas of migraine
88. Control of cerebral circulation in health and disease
89. Changes in regional cerebral blood flow during the course of classic migraine attacks
90. Regulation of regional cerebral blood flow during and between migraine attacks
91. Pial circulation and spreading depression of activity in the cerebral cortex
92. Spreading depression of activity in the cerebral cortex
93. Zur Frage der zentralen Ubertragung afferenter Impulse III. Mitteilung: das Vorkommen und die Bedeutung der Substanz P in den dorsalen Wurzeln des Ruckenmarks
94. Peripheral substance P neurones: afferent, efferent or both functions?
95. Sir Thomas Lewis's nocifensor system, histamine and substance‐P‐containing primary afferent nerves
96. Inhibition of neurogenic vasodilatation and plasma extravasation by substance P antagonists, somatostatin and (D‐MET2, PRO5) enkephalinamide
97. Analgesic effect of antagonists of substance P
98. Substance P as neurogenic mediator of antidromic vasodilation and neurogenic plasma extravasation
99. Inhibition of the A23187‐stimulated leukotriene and prostaglandin biosynthesis of rat basophil leukemia RBLI cells by nonsteroidal anti‐inflammatory drugs, anti‐oxidant, and calcium channel blockers
100. Vascular reactions of the skin to injury
101. Cholecystokinin‐8 (CCK8) immunoreactivity in cerebral arteries and pia arachnoid and the effect of unilateral trigeminal ganglionectomy
102. Pia arachnoid contains substance P originating from trigeminal neurons
103. Substance P–containing fibers in middle cerebral arteries: origin and ultrastructure
104. Immunohistochemical evidence for a substance P–containing trigeminovascular pathway to pial arteries in cats
105. Bronchial smooth muscle contraction induced by stimulation of capsaicin‐sensitive sensory neurons
106. Capsaicin‐sensitive vagal neurons involved in control of vascular permeability in rat trachea
107. Capsaicin‐induced desensitization of airway mucosa to cigarette smoke, mechanical and chemical irritants
108. Increased vascular permeability of rat nasal mucosa induced by SP and stimulation of capsaicin‐sensitive trigeminal neurons
109. Angiographic findings in herpes zoster arteritis
110. The innervation of the intracranial blood vessels and dural sinuses
111. Ocular responses to antidromic trigeminal stimulation, intracemeral prostaglandin E1 and E2, capsaicin and substance P
112. In the eye (D‐Pro2, D‐Trp7,9)‐SP is a substance P agonist, which modifies the responses to substance P, prostaglandin E1 and antidromic trigeminal nerve stimulation
113. Substance P binds to the formylpeptide chemotaxis receptor on the rabbit neutrophil
114. Substance P–immunoreactive peripheral branches of sensory neurons innervate guinea pig sympathetic neurons
115. Perivascular meningeal projections from the cat trigeminal ganglia: possible pathway for vascular headaches in man
116. Trigeminal projections to supratentorial pial and dural blood vessels in cats demonstrated by horseradish peroxidase histochemistry
117. Features peculiar to the trigeminal innervation
118. Note on a possible correspondence between the scotomas of migraine and spreading depression of Leao
119. In vitro release of immunoreactive substance P from putative afferent nerve endings in bovine pia arachnoid
120. Cat piaarachnoid contains immunoreactive substance P within neurons projecting from the fifth cranial nerve
121. VIP, CCK, and met‐enkephalin in pia arachnoid and cerebral arteries after unilateral lesions of cat trigeminal ganglia
122. Neurotransmitters and the fifth cranial nerve: is there a relation to the headache phase of migraine?
123. Enkephalin inhibits release of substance P from sensory neurons in culture and decreases action potential duration
124. Fluoride‐resistant acid phosphatase–containing neurones in dorsal root ganglia are separate from those containing substance P or somatostatin
125. Substance P as a transmitter candidate
126. The effects of lesioning the trigeminal superior cervical sympathetic, C2 and C3 ganglia on substance P in cat cerebral arteries
127. Some observations on headache
128. Focal hyperemia followed by spreading oligemia and impaired activation of rCBF in classic migraine
129. Release of substance P–like immunoreactivity from the dental pulp
130. Notes on the surgical treatment of migraine
131. Headache and hydration
132. Release of substance P–like immunoreactivity from isolated spinal cord of newborn rat
133. Specific stimulation of human T lymphocytes by substance P
134. Operative treatment of migraine and observations on the mechanism of vascular pain
135. Observations on the mechanism of headache produced by histamine
136. Use of substance P fragments to differentiate substance P receptors of different tissues
137. Chemical headaches
138. Experimental studies on headache: painsensitive structures of the head and their significance in headache
139. Serotonin neurons project to small blood vessels in the brain
140. Die Architektur des corticalen Sehenzentrums durch Selbstbeobachtung bei Flimmerscotom beleuchtet
141. Inhibition of antidromic and substance P–induced vasodilation by a substance P–antagonist
142. Pain pathways in migraine
143. Cluster headache after herpes zoster ophthalmicus
144. Calcium‐ and endothelial‐mediated vascular smooth muscle relaxation in rabbit aorta
145. Perivascular substance P–immunoreactive nerves in tracheobronchial tissue
146. A pharmacological approach to the elucidation of the role of different nerve fibers and receptor endings in mediation of pain
147. Synthesis of substance P
148. The dilatory action of adenosine on pial arteries of cats and its inhibition by theophylline
149. Trigeminal neurotomy and blood pressure responses from stimulation of lateral cerebral cortex of Macaca mulatta
150. Intrathecal morphine inhibits substance P release from mammalian spinal cord in vivo
151. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by substance P