Different modes of Ca channel gating behaviour favoured by dihydropyridine Ca agonists and antagonists

Nature

Volumn 311, Issue 5986, 1984, Pages 538-544

  Hess, Peter ^a   Lansman, Jeffry B ^a   Tsien, Richard W ^a  

^a YALE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIHYDRO 2,6 DIMETHYL 5 NITRO 4 [2 (TRIFLUOROMETHYL)PHENYL] 3 PYRIDINECARBOXYLIC ACID METHYL ESTER; 4 [2 (DIFLUOROMETHOXY)PHENYL] 1,4,5,7 TETRAHYDRO 2 METHYL 5 OXOFURO[3,4 B]PYRIDINE 3 CARBOXYLIC ACID ETHYL ESTER; CALCIUM ANTAGONIST; NIFEDIPINE; NIMODIPINE; NITRENDIPINE;

ANIMAL CELL; DRUG EFFICACY; DRUG INTERACTION; GUINEA PIG; HEART; HEART MUSCLE CELL; HEART VENTRICLE WALL; NONHUMAN;

ANIMAL; BAY-K-8644; CALCIUM; CALCIUM CHANNEL BLOCKERS; ELECTRIC CONDUCTIVITY; GUINEA PIGS; HEART; ION CHANNELS; KINETICS; NICOTINIC ACIDS; NIFEDIPINE; NIMODIPINE; NITRENDIPINE; RANIDAE; SARCOLEMMA; STRUCTURE-ACTIVITY RELATIONSHIP; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0021182780     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/311538a0     Document Type: Article

References (36)

1. Reuter, H. Nature 301, 569-574 (1983).
2. Tsien, R. W. A. Rev. Physiol 45, 341-358 (1983).
3. Fleckenstein, A. Calcium Antagonism in Heart and Smooth Muscle (Wiley, New York, 1983).
4. Flaim, S. F. & Zelts, R. Calcium Blockers (Urban and Schwarzenberg, Baltimore, 1982).
5. Schwartz, A. & Taira, N. (eds) Cire. Res., 52 (Suppl., part II), 1-181 (1983).
6. Scriabine, A. (ed.) Nitrendipine (Urban and Schwarzenberg, Baltimore, 1984).
7. Curtis, B. M. & Catterall, W. A. J. biol Chem., 258, 7280-7283 (1983).
8. Venter, J. C. et al. J. biol Chem., 258, 9344-9348 (1983).
9. Norman, R. I., Borsotto, M., Fosset, M. & Lazdunski, M. Biochem. biophys. Res. Commun., 111, 878-883 (1983).
10. Glossmann, H. & Ferry, D. R. Naunyn-Schmiedeberg’s Arch. Pharmac., 323, 279-291 (1983).
11. Schramm, M., Thomas, G., Towart, R. & Franckowiak, G. Nature 303, 535-537 (1983).
12. Truog, A. G. et al. in Calcium in Biological Systems (eds Rubin, R. P., Weiss, G. B. & Putney, J. W. Jr). (Plenum, New York, 1984).
13. Sanguinetti, M. C. & Kass, R. S. Biophys. J., 45, 394a (1984).
14. Hess, P., Lansman, J. B. & Tsien, R. W. Biophys. J., 45, 394a (1984).
15. Cohen, C. J. & Chung, M. Biophys. J., 45, 394a (1984).
16. Freedman, S. B. & Miller, R. J. Proc. natn. Acad. Sci, U.S.A., (in the press).
17. Kao, R. L. et al. Archs Biochem. Biophys., 203, 587-599 (1980).
18. Bean, B. P., Nowycky, M. C. & Tsien, R. W. Nature 307, 371-375 (1984).
19. Lee, K. S., Akaike, N. & Brown, A. M. J. Neurosci. Meth., 2, 51-78 (1980).
20. Hamill, O., Marty, A., Neher, E., Sakmann, B. & Sigworth, F. J. Pflügers Arch. ges. Physiol., 391, 85-100 (1981).
21. Cavalie, A., Ochi, R., Pelzer, D. & Trautwein, W. Pflügers Arch. ges. Physiol 398, 284-297 (1983).
22. Cachelin, A. B., dePeyer, J. E., Kokubun, S. & Reuter, H. Nature 304, 462-464 (1983).
23. Marban, E. & Tsien, R. W. Biophys J., 33, 143a (1981).
24. Lee, K. S. & Tsien, R. W. J. Physiol, Lond., (in the press).
25. Reuter, H., Stevens, C. F., Tsien, R. W. & Yellen, G. Nature 297, 501-504 (1982).
26. Fenwick, E. M., Marty, A, & Neher, E. J. Physiol., Lond., 331, 599-635 (1982).
27. Brum, G., Osterrieder, W. & Trautwein, W. Pflügers Arch ges. Physiol 401, 111-118 (1984).
28. Sanguinetti, M. C. & Kass, R. S. Cire. Rec., submitted.
29. Himori, N., Ono, H. & Taira, N. Jap. J. Pharmac., 26, 427-435 (1976).
30. Janis, R. A., Sarmiento, J. G., Maurer, S. C., Bolger, G. T. & Triggle, D. J. J. Pharm, exp. Ther, (in the press).
31. Fox, A. P., Hess, P., Lansman, J. B., Nowycky, M. C. & Tsien, R. W. J. Physiol, Lond., 353, 75P (1984).
32. Fox, A. P., Nowycky, M. C. & Tsien, R. W. Soc. Neurosci. Abs., 10, 526 (1984).
33. Lee, K. S. & Tsien, R. W. Nature 302, 790-794 (1983).
34. Glossmann, H., Lin, T., Rombusch, M. & Ferry, D. R. FEBS Lett., 160, 226-232 (1983).
35. Ochi, R., Hino, N. & Niimi, Y. Proc. Jap. Acad. Sci. B 60, 153-156 (1984).
36. Kokubun, S. & Reuter, H. Proc. natn. Acad. Sci. U.S.A., 81, 4824-4827 (1984).