Reduced elimination of ketoprofen in the elderly is not necessarily due to impaired glucuronidation.

British Journal of Clinical Pharmacology

Volumn 17, Issue 6, 1984, Pages 783-784

  Verbeeck, RK ^a   Wallace, SM ^a   Loewen, GR ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

CLOFIBRIC ACID; DIFLUNISAL; KETOPROFEN; PROBENECID;

AGED; DRUG ELIMINATION; EDITORIAL; HUMAN; LIVER; PHARMACOKINETICS; THERAPY;

AGED; AGING; CLOFIBRIC ACID; DIFLUNISAL; GLUCURONATES; HUMAN; KETOPROFEN; PHENYLPROPIONATES; PROBENECID;

EID: 0021137858     PISSN: 03065251     EISSN: 13652125     Source Type: Journal    
DOI: 10.1111/j.1365-2125.1984.tb02421.x     Document Type: Article

References (13)

1. Pharmacokinetics of ketoprofen in the elderly
2. Measurement of clofibric acid (CPIB) metabolites in plasma of patients on clofibrate therapy
3. Clofibrate disposition in renal failure and acute and chronic liver disease
4. Diflunisal‐probenecid co‐disposition: Michaelis‐Menten kinetics with competitive inhibition
5. Physiological disposition of fenoprofen in man. III Metabolism and protein binding of fenoprofen
6. Pharmacokinetics of ketoprofen in patients with chronic renal failure
7. Negligible excretion of unchanged ketoprofen, naproxen and probenecid in urine
8. Effects of probenecid on ketoprofen kinetics
9. Probenecid‐clofibrate interaction
10. Glucuronidation and disposition of drug glucuronides in patients with renal failure: a review
11. Clinical pharmacokinetics of nonsteroidal anti‐inflammatory drugs
12. Biotransformation of diflunisal and renal excretion of its glucuronides in renal insufficiency