Fibronectin modulation of cell shape and lipogenic gene expression in 3t3-adipocytes

Cell

Volumn 35, Issue 3 PART 2, 1983, Pages 657-666

  Spiegelman, Bruce M ^a,b   Ginty, Carol A ^a  

^a DANA FARBER CANCER INSTITUTE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; FATTY ACID SYNTHASE; FIBRONECTIN; GLYCEROL 3 PHOSPHATE DEHYDROGENASE; RADIOISOTOPE;

ADIPOCYTE; ANIMAL CELL; CELL SHAPE; CYTOSKELETON; GENE EXPRESSION; HEREDITY; HISTOLOGY; IN VITRO STUDY; LIPOGENESIS; MOUSE; NONHUMAN; SOFT TISSUE;

ACTINS; ADIPOSE TISSUE; ANIMAL; CELL DIFFERENTIATION; CELL LINE; CELLS, CULTURED; COLLAGEN; CYTOSKELETON; EXTRACELLULAR MATRIX; FIBRONECTINS; GENE EXPRESSION REGULATION; MICE; MICROTUBULES; RNA, MESSENGER; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TUBULIN;

EID: 0021069981     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/0092-8674(83)90098-3     Document Type: Article

References (50)

1. Restoration of normal morphology: adhesion and cytoskeleton in transformed cells by addition of a transformation-sensitive surface protein
2. Mechanisms of regulating tubulin synthesis in cultured mammalian cells
3. A film detection method for tritium-labeled proteins and nucleic acids in polyacrylamide gels
4. A rapid and sensitive method for the quantitation of microgram quantities of protein-dye binding
5. Cytochalasin inhibits the rate of elongation of actin filament fragments
6. The nuclear matrix: three-dimensional architecture and protein composition
7. Unpolymerized tubulin modulates the level of tubulin mRNAs
8. Evidence that microtubule depolymerization early in the cell cycle is sufficient to initiate DNA synthesis
9. Molecular analysis of cytoplasmic microtubules in situ: identification of both widespread and specific proteins
10. Binding of soluble form of fibroblast surface protein, fibronectin, to collagen
11. Metabolic obesity in man
12. Adipose conversion: a program of differentiation
13. Spontaneous heritable changes leading to increased adipose conversion in 3T3 cells
14. Specific interaction of cytochalasins with muscle and platelet actin filaments in vitro
15. Behavior of cells seeded in isolated fibronectin matrices
16. Relationships between fibronectin (LETS protein) and actin
17. Tyrosine-specific protein kinase activity is associated with the purified insulin receptor
18. Genetic and developmental control of multiple forms of L-glycerol-3-phosphate dehydrogenase
19. Adipose conversion of 3T3 cells depends on a serum factor
20. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
21. Nucleotide sequence and evolution of a mammalian β-tubulin messenger RNA
22. Dibutyryl cyclic AMP decreases glutamine synthetase in cultured 3T3-L1 adipocyte
23. An association between glutamine synthetase activity and adipocyte differentiation in cultured in 3T3-L1 cells
24. Organelle relationships in cultured 3T3-L1 preadipocytes
25. The display of microtubules in transformed cells
26. The structure of histone-depleted metaphase chromosomes
27. The influence of an adhesive cell surface protein on chondrogenic expression in vitro
28. Insulin activates a tyrosine-specific protein kinase in extracts of 3T3-L1 adipocytes and human placenta
29. Fibronectin delays the fusion of L6 lymphoblasts
30. Labeling deoxyribonucleic acid to high specific activity in vitro by nick-translation with DNA polymerse I
31. The ovalbumin gene is associated with the nuclear matrix of chicken oviduct cells
32. Action of cytochalasin D on cytoskeletal networks
33. Vinculin: a cytoskeletal target of the transforming protein of Rous sarcoma virus
34. Two-dimensional electrophoresis analysis of proteins synthesized during differentiation of 3T3-L1 preadipocytes
35. Decreases in tubulin and actin gene expression prior to morphological differentiation of 3T3-adipocytes
36. Control of specific protein biosynthesis during adipose conversion of 3T3 cells
37. Cyclic AMP-mediated control of lipogenic enzyme synthesis during adipose differentiation of 3T3 cells
38. Turnover of tubulin and the N site GTP in Chinese hamster ovary cells
39. Molecular cloning of mRNA from 3T3 adipocytes: regulation of mRNA content for glycerophosphate dehydrogenase and other differentiation-dependent proteins during adipocyte development
40. A clonal analysis of 3T3-L1 preadipose cells: role of insulin
41. Regulation of fatty acid synthetase concentration and activity during adipocyte differentiation
42. Fibronectin alters the phenotypic properties of cultured chick embryo chondroblasts
43. Microfilament bundles and cell shape are related to adhesiveness to substratum and are dissociable from growth control in cultured fibroblasts
44. Participation of one isozyme of cytosolic glycerophosphate dehydrogenase in the adipose conversion of 3T3 cells
45. Correlation between effects of 24 different cytochalasins on cellular structures and cellular events and those on actin in vitro
46. Cell surface protein partially restores morphology adhesiveness, and contact inhibition of movement of transformed fibroblasts
47. Quantitation of a transformation-sensitive, adhesive cell surface glycoprotein: decrease on several untransformed permanent cell lines
48. Transformation-sensitive cell surface protein: isolation, characterization and role in cellular morphology and adhesion