Serum cholesterol levels in homicidal offenders: A Low cholesterol level is connected with a habitually violent tendency under the influence of alcohol

Neuropsychobiology

Volumn 10, Issue 2-3, 1983, Pages 65-69

  Virkkunen, Matti ^a  

^a HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

Author keywords

Alcohol; Antisocial personality; Cholesterol; Habitual violence; Intermittent explosive disorder

Indexed keywords

ALCOHOL; CHOLESTEROL;

ADULT; ANTISOCIAL BEHAVIOR; CENTRAL NERVOUS SYSTEM; CHOLESTEROL BLOOD LEVEL; CLINICAL ARTICLE; FORENSIC MEDICINE; HOMICIDE; HUMAN; VIOLENCE;

ADULT; AGGRESSION; ALCOHOL DRINKING; ALCOHOLIC INTOXICATION; ANTISOCIAL PERSONALITY DISORDER; CHOLESTEROL; HOMICIDE; HUMAN; MALE; VIOLENCE;

EID: 0021051056     PISSN: 0302282X     EISSN: 14230224     Source Type: Journal    
DOI: 10.1159/000117987     Document Type: Article

References (37)

1. Evans, C.M.: Alcohol, violence and aggression. Br. J. Alcohol Alcoholism 15: 104-117 (1980).
2. Coid, J.: Alcoholism and violence. Drug Alcohol Depend. 9:1-13 (1982).
3. Wolfgang, M.E.: Patterns of criminal homicide (University of Pennsylvania Press, Philadelphia 1958).
4. Virkkunen, M.: Alcohol as a factor precipitating aggression and conflict behaviour leading to homicide. Br. J. Addict. 69: 149-154 (1974).
5. Rada. R.T.: Alcoholism and forcible rape. Am. J. Psychiat. 132: 444-446 (1975).
6. Johnson, S.D.; Gibson, L.; Linden, R.: Alcohol and rape in Winnipeg. J. Stud. Alcohol 39: 1887-1898 (1978).
7. Hanks, S.E.; Rosenbaum, C.P.: Battered women. A study of women who live with violent alcoholabusing men. Am. J. Orthopsvchiat. 47: 291-294 (1977).
8. Byles, J.A.: Violence, alcohol problems and other problems in disintegrating families. J. Stud. Alcohol 39: 551-553 (1978).
9. Task Force on Nomenclature and Statistics of the American Psychiatric Association: Diagnostic and statistical manual of mental disorders (American Psychiatric Association. Washington 1980).
10. Neziroglu, F.: Behavioral and organic aspects of aggression; in Obiols, Ballus, Gonzales-Monchus, Pujol, Biological psychiatry today, pp. 1215-1222 (Elsevier/North Holland, Amsterdam 1979).
11. Yarura-Tobias, J.A.; Neziroglu, F.: Aggressive behavior, brain dysrhythmia and glucose dysfunction. A new syndrome. J. orthomol. Psychiat. 4: 182-188 (1975).
12. Yarura-Tobias, J.A.; Neziroglu, F.: Aggressive behavior, clinical interfaces; in Valzeìli, Morgese, Aggression and violence. A psychobiological and clinical approach, pp. 195-210 (Edizioni centra culturale e congressi, Saint Vincent 1981).
13. Virkkunen, M.: Reactive hypoglycemic tendency among habitually violent offenders. A further study by means of the glucose tolerance test. Neuropsychobiology 8: 35-40 (1982).
14. Virkkunen, M.: Insulin secretion during the glucose tolerance test in antisocial personality. Br. J. Psychiat (in press, 1982).
15. Virkkunen. M.; Huttunen, M.O.: Evidénce for abnormal glucose tolerance test among violent offenders. Neuropsychobiology 8: 30-34(1982).
16. Virkkunen, M.: Serum cholesterol in antisocial personality. Neuropsychobiology 5: 27-30 (1979).
17. Stewart, M.A.; Stewart, S.G.: Serum cholesterol in antisocial personality. A failure to replicate earlier findings. Neuropsychobiology 7:9-11 (1981).
18. Spellacy, F.: Neuropsychological differences between violent and nonviolent adolescents. J. clin. Psychol. 33: 966-968 (1977).
19. Feighner. J.P.; Robins, E.; Guze, S.E.; Woodruff, R.A.; Winokur. G.; Munoz, R.: Diagnostic criteria for use in diagnostic research. Archs gen. Psychiat. 26: 57-63 (1972).
20. Trinder. P.: Determination of cholesterol in blood using cholesterol oxidase with alternative oxygen acceptor. Ann. clin. Biochem. 6:24-27 (1969).
21. Wahlefeld, A.W.: Triglycerides determination after enzymatic hydrolysis; in Bergmeyer, Methods of enzymatic analysis; 2nd ed., vol. 4, pp. 1831-1835 (Academic Press, London 1974).
22. Marks, V.: Alcohol and carbohydrate metabolism. Clin. Endocrinol. Metab. 7: 333-348 (1978).
23. Persson, B.: Lipoprotein lipase activity of human adipose tissue in health and in some diseases with hyperlipidemia as a common feature. Acta med. scand. 193: 457-462 (1973).
24. Pykälistö, O.J.; Smith. P.H.; Brunzell. J.D.: Determinants of human adipose tissue lipoprotein lipase. Effect of diabetes and obesity on basaland dietinduced activity. J. clin. Invest. 56: 1108-1117 (1975).
25. Brown, M.S.; Goldstein, J.L.: Familial hypercholesterolemia: a genetic defect in the lowdensity lipoprotein receptor. New Engl. J. Med. 294: 1386-1390(1976).
26. Brown, M.S.; Goldstein, J.L.: Receptormediated endocytosis. Insight from the lipoprotein receptor system. Proc. natn. Acad. Sci. USA 76: 3330-3337 (1979).
27. Chait, A.; Bierman, E.L.; Albers, J.J.: Lowdensity lipoprotein receptor activity in cultured human skin fibroblasts. Mechanism of insulininduced stimulation. J. clin. Invest. 64: 1309-1319 (1979).
28. Henze, K.; Chait, A.: Lysosomal enzyme activities and low density lipoprotein receptors in circulating mononuclear cells. Effect of insulin therapy in diabetic subjects. Diabetologia 20: 625-629 (1981).
29. Brown, G.L.; Goodwin, F.K.; Ballenger, J.C.; Goyer, P.F.; Major, L.F.: Aggression in humans correlates with cerebrospinal fluid amine metabolites. Psychiat. Res. 1: 131-139 (1979).
30. Brown, G.L.; Ebert, M.H.: Goyer, P.F.; Jimmerson, D.C.; Klein, W.J.; Bunney, W.E.; Goodwin, F.K.: Aggression, suicide and serotonin. Relationships to CSF amine metabolites. Am. J. Psychiat. 139: 741-746 (1982).
31. Valzelli, L.: Aggression and violence. A biological essay of the distinction; in Valzelli, Morgese, Aggression and violence. A psychobiological and clinical approach, pp. 39-60 (Edizioni centra culturale e congressi, Saint Vincent 1981).
32. Ásberg, M.; Träskman, L.; Thorén, P.: 5-HIAA in the cerebrospinal fluid. A biochemical suicide predictor? Archs gen. Psychiat. ii: 1193-1197 (1976).
33. Träskman, L.; Åsberg, M.; Bertilsson, L.; Sjöstrand, L.: Monoamine metabolites in CSF and suicidal behavior. Archs gen. Psychiat. 38: 631-641 (1981).
34. Feldman. J.M.; Lebowitz, H.E.: A serotonergic mechanism for the control of insulin secretion. Trans. Ass. Am. Physns 85: 279-294 (1972).
35. Wilson, J.P.; Downs, R.W., Jr.; Feldman, J.M.; Lebowitz, H.E.: Beta cell monoamines. Further evidence for their role in modulating insulin secretion. Am. J. Physiol. 227: 305-312 (1974).
36. Pulido, O.M.; Bencosme, S.A.; Bold, M.L. de; Bold, A.J. de: Intracellular pancreatic B cell serotonin and the dynamics of insulin release. Diabetologia 15: 197-204 (1978).
37. Pontiroli, A.E.; Viberti, G.C.; Tognetti, A.; Pozza, G.: Effect of metergoline, a powerful and longacting antiserotonergic agent, on insulin secretion in normal subjects and in patients with chemical diabetes. Diabetologia 11: 165-167 (1975).