Biochemical and physiologic effects of thyroid hormone on cardiac performance

Progress in Cardiovascular Diseases

Volumn 25, Issue 5, 1983, Pages 435-464

  Morkin, E ^a   Flink, I L ^a   Goldman, S ^a  

^a UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROPRANOLOL; THYROID HORMONE;

BIOCHEMISTRY; DRUG EFFICACY; DRUG MECHANISM; DRUG SENSITIVITY; DRUG THERAPY; ENDOCRINE SYSTEM; HEART; HEART FUNCTION; HUMAN; HYPERTHYROIDISM; PHARMACOLOGY; PHYSIOLOGY; REVIEW; THERAPY;

ADENOSINE TRIPHOSPHATE; ADENOSINETRIPHOSPHATASE; ANIMAL; BLOOD CIRCULATION; DOGS; ELECTROPHYSIOLOGY; GUINEA PIGS; HEART; HEMODYNAMICS; HUMAN; HYPERTHYROIDISM; HYPOTHYROIDISM; ISOENZYMES; MYOCARDIUM; MYOSINS; RABBITS; RATS; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.; SYMPATHETIC NERVOUS SYSTEM; THYROXINE; TRIIODOTHYRONINE;

EID: 0021025422     PISSN: 00330620     EISSN: None     Source Type: Journal    
DOI: 10.1016/0033-0620(83)90004-X     Document Type: Article

References (236)

1. Report of a Committee of the Clinical Society of London to Investigate the Subject of Myxedema
2. Evidence for a new cardiac myosin species in thyrotoxic rabbit
3. Thyroid hormone stimulates synthesis of a cardiac myosin isozyme. Comparison of the two-dimensional electrophoretic patterns of the cyanogen bromide peptides of cardiac myosin heavy chains from euthyroid and thyrotoxic rabbits
4. Thyroxine induced redistribution of isozymes of rabbit ventricular myosin [abstr]
5. Electrophoretic analysis of multiple forms of rat cardiac myosin: effects of hypophysectomy and thyroid replacement
6. ATPase activity of myosin correlated with speed of muscle shortening
7. A comparative study of heart myosin ATPase and light subunits from different species
8. Thyroid hormone action at the cellular level
9. The hemodynamics of thyrotoxicosis in man with special reference to coronary blood flow and myocardial oxygen consumption
10. The circulation in hyperthyroidism A cardiac catherization study before and after treatment
11. A correlation of clinical and hemodynamic studies in patients with hyperthyroidism with and without congestive heart failure
12. Determination of cardiac output and other hemodynamic data in patients with hyper- and hypo-thyroidism using dye dilution technique
13. Experimental hyperthyroidism I Hemodynamics and contractility in situ
14. Perisistence of an accelerated rate in the isolated hearts and auricles of thyrotoxic rabbits: response to iodides, thyroxine and epinephrine
15. The tachycardia of experimental hyperthyroidism
16. The tachycardia, time factor, survival period and seat of action of thyroxine in the perfused heart of thyroxinized rabbits
17. Influence of the thyroid state on the intrinsic contractile properties and energy stores of the myocardium
18. The influence of thyroid hormone on myocardial contractility
19. Experimental hypoerthyroidism. II. Mechanics of contraction and relaxation of isolated ventricular myocardium
20. Influence of hyperthyroidism on glycerol-extracted cardiac muscle from rabbits
21. Influence of the thyroid state on left ventricular tension-velocity relationship in the intact, sedated dog
22. Effect of the thyroid state on myocardial contractility and ventricular ejection rate in man
23. The short cardiac pre-ejection period: an index to thyrotoxicosis
24. Clinical studies of the cardiac performance by means of trans-septal left heart catherization. III. Left ventricular function in high output heart disease, especially in hyperthyroidism
25. Left ventricular function and hyperthyroidism
26. Echocardiographic left ventricular function in thyrotoxicosis
27. Effects of thyroid hormone on left ventricular function in patients treated for thyrotoxicosis
28. Left ventricular performance in conscious thyrotoxic calves
29. Adrenergic control of myocardial contractility in conscience hyperthyroid dogs
30. Effects of thyroid hormones on certain nonendocrine organ systems
31. The effect of altrered thyroid state on atrial intracellular potentials
32. Atrial electrophysiology in experimental hyperthyroidism in rabbits
33. Action of thyroid hormone on the transmembrane potentials from sinoatrial node cells and atrial muscle cells in isolated atria of rabbits
34. Effect of thyroid hormone on canine Purkinje fiber transmembrane potential
35. The occurrence and pathogenesis of cardiac hypertrophy in Graves disease
36. Role of ornithine decarboxylase in cardiac growth and hypertrophy
37. Regression of cardiac hypertrophy of various origins
38. Effect of thyroxine on growth and function of cardiac muscle
39. Effect of thyroxine on ventricular myocardial contractility and ATPase activity in guinea pigs
40. Actomyosin content of the heart in thyroxin-induced hypertrophy
41. Experimental hyperthyroidism in the dog and the effect of salvariectomy
42. Cardiac failure in the dog as a consequence of exogenous hyperthyroidism
43. The heart in the experimental hyperthyroidism with special reference to its histology
44. A study of the heart in hyperthyroidism
45. Myocarditis. A general review, with an analysis of two hundred and forty cases
46. Cardiovascular effects of thyroxine
47. Acute thyrotoxicosis in the rabbit: Changes in cardiac myosin, contractility and ultrastructure
48. Diastolic geometry and sarcomere lengths in the chronically dilated canine left ventricle
49. Adrenal medullary and thyroid relationships
50. Effect of injected norepinephrine and sympathetic nerve stimulation in hypothyroid and hyperthyroid dogs
51. An experimental evaluation of the reputed influence of thyroxine on the cardiovascular effects of catecholamines
52. Studies of the reputed augmentation of the cardiovascular effects of catecholamines in patients with spontaneous hyperthyroidism
53. Relation of thyroid state to myocardial catecholamine concentration
54. Studies on the metabolism of aromatic amines in relation to altered thyroid function
55. Urinary catecholamines and their metabolites in hyperthyroidism and hypothyroidism
56. Plasma catecholamines in hypothyroidism and hyperthyroidism
57. Increased levels of plasma noradrenalin in hypothyroidism
58. Serum dopamine-beta-hydroxylase in thyroid disorders
59. Decreased serum dopamine-beta-hydroxylase in hyperthyroidism
60. Thyroid hormone regulation of β-adrenergic number
61. β-Adrenergic receptors in rat heart Effects of thyroidectomy
62. Thyroxine and propylthiouracil effects in vivo on alpha- and beta-adrenergic receptors in rat heart
63. α-Adrenergic receptor in rat heart. Effects of thyroidectomy
64. Thyroid hormone regulation of alpha-receptors Studies in rat myocardium
65. Cardiovascular and metabolic interrelationsips between thyroxine and the sympathetic nervous system
66. Thyroid hormone regulation of cardiac glycogen metabolism
67. The effect of triiodothyronine pretreatment on catecholamine-induced rat cardiac phosphorylase activation
68. Enhancement by thyroid hormone treatment of norepinephrine-induced phosphorylase activation in the rat heart
69. The effect of triodothyroinine on cyclic AMP, phosphorylase, and adenyl cyclase in rat heart
70. The effect of noradrenaline and tyramine on cardiac contractility, cyclic AMP, and phosphorylase a in normal and hyperthyroid rats
71. Normal adenyl cyclase activity in hyperthyroid cats
72. Cyclic AMP-dependent protein kinase activation in hearts from euthyroid and hyperthyroid animals
73. The effects of thyroxine on rat heart adenosine 3′-5′-monophosphate, phosphorylase b kinase and phosphorylase a activity
74. Effect of isoproterenol on phosphorylase activation in the hyperthyroid rat heart
75. Effects of beta-adrenergic receptor blockade in normal subjects before, during, and after triiodothyronine-induced hypermetabolism
76. Pharmacodynamic effects of beta-adrenergic receptor blockade in patients with hyperthyroidism
77. Myocardial contractility, and the effects of beta-adrenergic blockade in hypothyroidism and hyperthyroidism
78. Influence of beta sympathetic blockade (propranolol) on the hemodynamics of hyperthyroidism
79. The enhanced myocardial contractility of thyrotoxicosis
80. Experimental hyperthyroidism. III. Contractile responses to propranolol of the intact heart and of the isolated ventricular myocardium
81. Beta-adrenergic blockade with propranolol in conscious euthryroid and thyrotoxic calves: dosage requirements and effects on heart rate and left ventricular performance
82. Plasma protein binding of propranolol and isoprenalin in hyperthyroidism and hypothyroidism
83. 4-Hydroxypropranolol and its glucuronide after single and long-term doses of propranolol
84. Effect of atropine on the tachycardia of hyperthyroidism
85. Role of the autonomic nervous system in the resting tachycardia of experimental hyperthyroidism
86. Blood flow to the forearm and calf. IV. Thyroid-activity: observations of the relation of blood flow to metabolic rate
87. Peripheral circulation and metabolic consequences of thyrotoxicosis IV Blood flow in resting and working calf muscle in patients with thyrotoxicosis before and after treatment
88. Mechanism of certain abnormalities of the circulation to the limbs in thyrotoxicosis
89. A correlative study of the cardiac output and the hepatic circulation in hyperthyroidism
90. Cerebral circulation and metabolism in hyperthyroidism
91. Peripheral circulation and metabolic consequences of thyrotoxicosis. VII. Venomotor tone at rest in thyrotoxic patients before and after treatment
92. Hemodynamic effects of peripheral vasocontriction in normal and thyrotoxic subjects
93. Analysis of the ventricular pumping capacity as a function of input and output pressure loads
94. Simple model of the circulation
95. The cardiac and vascular factors that determine systemic blood flow
96. Effects of splanchnic nerve stimulation on cardiac preload, afterload and output in cats
97. Effect of hematocrit on venous return
98. Compensations of cardiac output and other circulatory functions in areflex dogs with large A-V fistulae
99. Involvement of an arginyl residue in the catalytic activity of myosin heads
100. Phenylglyoxal modification of cardiac myosin S-1. Evidence for essential arginine residues at the active site
101. The enzymic properties of N-ethylmaleimide modified myosin
102. Reaction of 5,5′-dithiobis(d-nitrobenzoic acid) with myosin subfragment one: evidence for formation of a single protein disulfide with trapping of metal nucleotide at the active site
103. Evidence for the role of myosin in calcium sensitization of actomyosin
104. Transient state phosphate production in the hydrolysis of nucleoside triphosphates by myosin
105. Mechanism of adenosine triphosphate hydrolysis by actomyosin
106. The magnesium ion-dependent adenosine triphosphatase of myosin. Two-step processes of adenosine triphosphate association and adenosine diphosphate dissociation
107. Intermediate states of subfragment 1 and actosubfragment 1 ATPase: reevaluation of the mechanism
108. The magnesium-ion-dependent adenosine triphosphatase of bovine cardiac myosin and its subfragment-1
109. Comparison of the myosin and actomyosin ATPase mechanisms of the four types of vertebrate muscles
110. Heavy meromyosin evidence for a refractory state unable to bind actin in the presence of ATP
111. Further studies on the interaction of actin with heavy meromyosin and subfragment-1 in the presence of ATP
112. Mechanism of the actomyosin ATPase: effect of actin on the ATP hydrolysis step
113. Mechanism of actomyosin in ATPase and the problem of muscle contraction
114. The relation of muscle biochemistry to muscle physiology
115. Hemodynamic changes in hypophysectomized rats
116. Cardiac myofibrillar ATPase activity in hypophysectomized or thyroidectomized rats
117. Hormonal control of cardiac myosin adenosine triphosphatase in the rat
118. Effects of L-thyroxine on the primary structure of cardiac myosin
119. Effect of thyroxine on ventricular myocardial contractility and ATPase activity in guinea pigs
120. Quantitative and qualitative characterization of cardiac actomyosin in thyroxine-induced hypertrophy
121. The effect of hyperthyroidism on the sarcoplasmic reticulum and myosin ATPase of dog heart
122. Effect of the thyroid state on the enzymatic characteristics of cardiac myosin. A difference in behavior of rat and rabbit cardiac myosin
123. Effects of N-ethylmaleimide on the ATPase activities of cardiac myosin from thyrotoxic rabbits
124. Enzymatic properties of native and N-ethylmaleimide-modified cardiac myosin from normal and thyrotoxic rabbits
125. Phosphorylation and adenosine triphosphatase activity of myofibrils from thyrotoxic rabbit hearts
126. Kinetic comparison of normal and thyrotoxic bovine cardiac myosin subfragment-1 (abstract)
127. Aggregation linked kinetic heterogenity in bovine cardiac myosin subfragment-1
128. Enzymatic properties of the heavy meromyosin subfragment of cardiac myosin from normal and thyrotoxic rabbits
129. Species and age-dependent changes in the relative amounts of cardiac myosin isoenzymes in mammals
130. Enolase isoenzymes as markers of differentiation in teratocarcinoma cells and normal tissues of mouse
131. Changes in lactate dehydrogenase composition of heart with right ventricular hypertrophy
132. The role of isozymes in metabolic pathways as the basis for the biological role of isozymes
133. Light chains of myosin from white, red and cardiac muscles
134. A new cardiac myosin characterized from the canine atria
135. Atrial and ventricular myosins contain different heavy chain species
136. Cardiac atrial myosin adenosine triphosphatase of animals and humans
137. Human atrial and ventricular myosin light-chain subunits in the adult and during development
138. 1
139. Myosin types and fiber types in cardiac muscle. I. Ventricular myocardium
140. Myosin light chain patterns of individual fast and slow-twitch fibres of rabbit muscles
141. 2 thiols from thyrotoxic cardiac myosin
142. Cyanogen bromide peptide from bovine cardiac myosin containing two essential thiols. Evidence for sequence homology with skeletal myosin in the region of the active site
143. Thyroid hormones: Crystal structure, molecular conformation, binding, and structure-function relationship
144. Ribonucleic acid synthesis during the early action of thyroid hormones
145. Reversal of thyroxine-induced hypermetabolism by puromyocin
146. Enhanced oxidation of α-glycerophosphate by mitochondria of thyroid-fed rats
147. Limited capacity binding sites for L-triiodothyronine in rat liver nuclei. Localization to chromatin and partial characterization of the 1-triodothyronine-chromatin complex
148. Thyroid hormone action: demonstration of putative nuclear receptors in human lymphocytes
149. Binding of selected iodothyronine analogues to receptor sites of isolated rat hepatic nuclei
150. Molecular interactions between thyroid hormone analogs and the rat liver nuclear receptor. Partitioning of equilibrium binding free energy changes into substituent group interactions
151. Thyroid-hormone receptor-containing fragment released from chromatin by deoxyribonuclease 1 and micrococcal nuclease
152. Solubilized nuclear “receptors” for thyroid hormone
153. Protein-DNA and protein-hormone interactions in prealbumin: a model of the thyroid hormone receptor
154. Myocardial chromatin activation in experimental hyperthyroidism in rats
155. Enhanced myocardial RNA synthesis in hyperthyroid rats: role of endogenous RNA polymerases
156. Messenger RNA content and complexity of euthyroid and hypothyroid rat liver
157. Thyroxine: Effects on amino acid incorporation into protein in vivo
158. Synthesis and degradation of myocardial protein during the development and regression of thyroxine-induced cardiac hypertrophy in rats
159. Effect of experimental hyperthyroidism on protein turnover in skeletal and cardiac muscle
160. Increased myocardial cathepsin D activity during regression of thyrotoxic cardiac hypertrophy
161. 2μ globulin
162. 2μ globulin in rat liver
163. Triiodothyronine stimulates specifically growth hormone mRNA in rat pituitary tumor cells
164. Changes in the hepatic levels of messenger ribonucleic acid for maleic enzyme during induction by thyroid hormone or diet
165. 1 cells
166. 1 cells. Evidence for two functional components of nuclear-bound receptor and relationship to the induction of growth hormone synthesis
167. Thyroid and glucocorticoid hormone synergistically control growth hormone mRNA in cultured GH cells
168. Permissive role of L-thyroxine induction of pancreatic amylase by cortisol in neonatal rats
169. Action of triiodothyroinine on the synthesis of rat ventricular myosin isozymes
170. Thyroid-induced alterations in myocardial sodium- and potassium-activated adenosine triphosphatase, monovalent cation active transport, and cardiac glycoside binding
171. Effects of thyroid status on electrolyte distribution in rat tissues
172. 2+-activated ATPase of cardiac sarcoplasmic reticulum in hyper- and hypothyroidism
173. Enhanced phosphorylation of myocardial sarcoplasmic reticulum in experimental hyperthyroidism
174. Enhanced contractile response and protein kinase activation to threshold levels of β-adrenergic stimulation in hyperthyroid rat heart
175. Changes in the activity of sarcoplasmic reticulum fragments and actomyosin isolated from skeletal muscle of thyroxine-treated cats
176. Metabolic effects of thyroxine in vitro
177. The mode of action of thyroxin
178. Evaluation of oxidative phosphorylation in hearts from cuthyroid, hypothyroid, and hyperthyroid rats
179. Thyroid hormone action on mitochondria. IV. Redox states of intrinsic pyridine nucleotides in hypothyroidism and the influence of L-thyroxine
180. The functional significance of altered tension dependent heat in thyrotoxic myocardial hypertrophy
181. Thyroid hormone action: the mitochondrial pathway
182. In vitro binding of L-triiodothyronine to receptors in rat liver nuclei
183. Cycloleucine transport in isolated rat thymocytes: In vitro effects of triiodothyronine and thyroxine
184. 3H]glucose uptake in cultured chick embryo heart cells
185. Increased phospholipid methylation in the myocardium of hyperthyroid rats
186. On the mechanism of action of thyroxine, an amino acid analog of tyrosine
187. Localization of triiodothyronine in nerve ending fractions of rat brain
188. Correlation of clinical hemodynamic studies in patients with hypothyroidism
189. Das Myxodemherz
190. Pericardial effusion A constant early and major factor in the cardiac syndrome of hypothyroidism
191. Systolic time intervals in thyroid disease
192. Noninvasive evaluation of cardiac function in hypothyroidism
193. Myocardial function in hypothyroidism
194. Cardiac function in primary hypothyroidism
195. Cardiomyopathy of hypothyroidism revisited; are children different than adults?
196. Experimental hypothyroidism: depression of myocardial contractile function and hemodynamics and their reversibility by substitution with thyroid hormones
197. A possible explanation for myxedema and hypercholesterolemia in hypothyroidism
198. Influence of thyroid hormones and related compounds on cholesterol biosynthesis and degradation A review
199. Serum cholesterol, lipoproteins, and the risk of coronary heart disease. The Framingham Study
200. Arteriosclerosis in thyroid deficiency
201. The heart in myxedema; correlation of physical and post-mortem finding
202. Myxedema and heart-failure
203. Hypercholesterolemia, myxedema and atherosclerosis
204. Myxedema and coronary artery disease—A comparative autopsy study
205. 2+ affinity of myosin B from hypertrophied nonfailing cat hearts
206. Myofibrillar ATPase, DNA and hydroxyproline content of human hypertrophied heart
207. Isolation and characterization of myosin from subjects with asymmetric septal hypertrophy
208. Canine cardiac myosin with special reference to pressure overload cardiac hypertrophy. II. Myosin ATPase
209. Myofibrillar and actomyosin adenosine-tri-phosphatase in experimental aortic insufficiency
210. Correlation between cardiac muscle myosin ATPase activity and velocity of muscle shortening
211. Studies on the substructure of myosin in cardiac hypertrophy; characterization of light chains
212. Structural and functional properties of myosin associated with the compensatory cardiac hypertrophy in the rabbit
213. 2+-activated myosin adenosine triphosphatase in chronic cannine congestive heart failure
214. Effects of physical training on cardiac myosin ATPase activity
215. Myosin isozyme changes in several models of rat cardiac hypertrophy
216. The adaptive changes in the isoenzyme pattern of myosin from hypertrophied rat myocardium as a result of pressure overload and physical training
217. Effect of exercise on collateral development in dogs with normal coronary arteries
218. Contractile function and myofibrillar ATPase activity in exercise-trained dog heart
219. The effect of certain high cardiac output states on dog heart myosin ATPase
220. Chronological effects of mild pressure overload on myosin ATPase activity in the canine right ventricle
221. Development of the hypothalamic-pituitary-thyroid axis in the neonatal rat
222. The prematurely promoted formations of liver enzymes in suckling rats
223. Reduced myocardial actomyosin adenosine triphosphatase activity in the aging male fisher rat
224. Age-associated alterations in myocardial contractile properties
225. Diminished inotropic responsiveness to ouabain in aged rat myocardium
226. Metabolism of thyroid hormones during aging
227. Diabetes mellitus induced changes in cardiac myosin of the rat
228. The effects of streptozotocin induced diabetes in rats on cardiac contractile proteins
229. Thyroxine levels in streptozotocin- insulin- and glibenclamide-treated rats
230. 3) in systemic illnesses
231. Decrease in rat cardiac myosin ATPase with aortic constriction Prevention by thyroxine treatment