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Volumn 12, Issue 4, 1983, Pages 359-372

Clinical pharmacology and toxicology of cyclophosphamide: emphasis on use in rheumatic diseases

(1)  Kovarsky, Joel a  

a NONE

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXYCYCLOPHOSPHAMIDE; 4 OXOCYCLOPHOSPHAMIDE; ACROLEIN; ALDOPHOSPHAMIDE; ALLOPURINOL; CHLORAMBUCIL; CHLOROQUINE; CYCLOPHOSPHAMIDE; DIETHYLSTILBESTROL; MESNA; PHOSPHORAMIDE MUSTARD; PREDNISOLONE;

EID: 0020962068     PISSN: 00490172     EISSN: None     Source Type: Journal    
DOI: 10.1016/0049-0172(83)90016-1     Document Type: Article
Times cited : (59)

References (228)
  • 1
    • 84912432087 scopus 로고
    • Cytostats with effects in chronic inflammation
    • 9th ed, JR Vane, SH Fereira, Handbook of Experimental Pharmacology, Springer-Verlag, New York
    • (1979) Antiinflammatory drugs , vol.50-52 , pp. 531-578
    • Brune1    Whitehouse2
  • 5
    • 0002149824 scopus 로고
    • Drugs used in cancer chemotherapy
    • CM Haskell, WB Saunders, Philadelphia
    • (1980) Cancer Treatment , pp. 53-123
    • Haskell1
  • 8
    • 0001482314 scopus 로고
    • Synthese und Abbau cytostatisch wirksamer cyclischer N-Phosphamidester des Bis-(Bchlorathyl)-amins
    • (1958) Angewandte Chemie , vol.70 , pp. 539-544
    • Arnold1    Bourseaux2
  • 10
    • 84915114552 scopus 로고
    • Immunosuppressive therapy in rheumatoid arthritis
    • (1974) J Rheumatol , vol.1 , pp. 364-373
    • Urowitz1
  • 11
    • 0018859828 scopus 로고
    • Disease-modifying drugs for progressive rheumatoid arthritis
    • 9th ed
    • (1980) Mayo Clin Proc , vol.55 , pp. 161-179
    • Bunch1    O'Duffy2
  • 12
    • 0017186257 scopus 로고
    • Immunosuppressive agents in lupus nephritis: A critical analysis
    • (1976) Medicine , vol.55 , pp. 239-250
    • Wagner1
  • 16
    • 0018143999 scopus 로고
    • Quantitation by gas chromatography-chemical ionization mass spectrometry of cyclophosphamide, phosphoramide mustard, and nornitrogen mustard in the plasma and urine of patients receiving cyclophosphamide therapy
    • (1978) Cancer Res , vol.38 , pp. 408-415
    • Jardine1    Fenselau2    Appler3
  • 17
    • 0016422915 scopus 로고
    • The quantitation of cyclophosphamide in human blood and urine by mass spectrometry-stable isotope dilution
    • (1975) Clin Chim Acta , vol.58 , pp. 61-69
    • Jarman1    Gilby2    Foster3
  • 19
    • 0014557404 scopus 로고
    • Effect of microsomal enzyme modifiers on toxicity and therapeutic activity of cyclophosphamide in mice
    • (1969) Arch Int Pharmacodyn , vol.180 , pp. 391-401
    • Hart1    Adamson2
  • 20
    • 0015292572 scopus 로고
    • The effect of phenobarbitol or 2-diethyl-aminoethyl-2, 2-diphenylvalerate on the activation of cyclophosphamide in vivo
    • (1972) J Pharmacol Exp Ther , vol.180 , pp. 475-483
    • Field1    Gang2    Klein3
  • 21
    • 0015308178 scopus 로고
    • Therapeutic efficacy of cyclophosphamide as a function of its metabolism
    • (1972) Cancer Res , vol.32 , pp. 535-542
    • Sladek1
  • 24
    • 70449209684 scopus 로고
    • Erst Erfahrungen in der Behandlung maligner Tumoren mit einem neuen N-Lost-Phosphamidester
    • (1958) Dtsch Med Wochenschr , vol.83 , pp. 458-462
    • Gross1    Lambers2
  • 26
    • 0007606815 scopus 로고
    • Zur pharmakologischen Charakterisierung zyklischer N-Lost-Phosphamideste rals Krebs-Chemotherapeutica
    • (1958) Arzneim-Forsch , vol.8 , pp. 1-9
    • Brock1
  • 28
  • 29
    • 0014836063 scopus 로고
    • Enzymatic basis of cyclophosphamide activation by hepatic microsomes in the rat
    • (1970) J Pharmacol Exp Ther , vol.174 , pp. 206-210
    • Cohen1    Jao2
  • 30
    • 18344378294 scopus 로고
    • Studies on the mechanisms of action of cytoxan: Evidence of activation in vivo and in vitro
    • (1961) Cancer Res , vol.21 , pp. 57-63
    • Foley1    Friedman2    Drolet3
  • 33
    • 0004808918 scopus 로고
    • Primary evaluation of alkylating agent-cyclohexylamine salt of N, N-bis (2-chlorethyl) phosphorodiamidic acid (NSC-69945; OMF-59) in experimental antitumor assay systems
    • (1966) Cancer Chemother Rep , vol.50 , pp. 629-639
    • Maddock1    Handler2    Friedman3
  • 34
    • 0013680294 scopus 로고
    • Formation of the cytotoxic aldehyde acrolein during in vitro degradation of cyclophosphamide
    • (1971) Nature , vol.233 , pp. 250
    • Alarcon1    Meienhofer2
  • 35
    • 0015786178 scopus 로고
    • Bioassay and relative cytotoxic potency of cyclophosphamide metabolites generated in vitro and in vivo
    • (1973) Cancer Res , vol.33 , pp. 1150-1158
    • Sladek1
  • 36
    • 0011549229 scopus 로고
    • Uber Beziehugen zwischen chemischer konstitution und cancerotoxischer Wirkung in der Reihe de Phosphamidester de Bis(B-chlorathyl)-amins
    • (1961) Arzneim-Forsch , vol.11 , pp. 143-158
    • Arnold1    Bourseaux2    Brock3
  • 37
    • 0016736779 scopus 로고
    • Identification of phosphoramidic acid mustard as a human metabolite of cyclophosphamide
    • (1975) Cancer Res , vol.35 , pp. 1453-1457
    • Fenselau1    Kan2    Billets3
  • 44
    • 0018770036 scopus 로고
    • Comparative effects of cyclophosphamide, isophosphamide, 4-methylcyclophosphamide and phosphoramide mustard on murine hematopoietic and immunocompetent cells
    • (1979) J Natl Cancer Inst , vol.62 , pp. 975-981
    • Sensenbrenner1    Marini2    Colvin3
  • 45
    • 0015962416 scopus 로고
    • Some (pharmacological) properties of chloracetaldehyde, an oxidation product and potential metabolite of cyclophosphamide
    • (1974) Agents Actions , vol.4 , pp. 34-43
    • Whitehouse1    Beck2    Kacena3
  • 46
    • 0016714779 scopus 로고
    • Timely appraisal: Estopic (extracellular) nucleic acid as a drug target, especially in rheumatoid arthritis and certain cancers (?)
    • (1975) Agents Actions , vol.5 , pp. 508-511
    • Whitehouse1
  • 49
    • 0019509869 scopus 로고
    • Clinical infections, antibiotics and immunosuppression: A puzzling relationship (editorial)
    • (1981) Am J Med , vol.71 , pp. 334-336
    • Miller1    North2
  • 52
    • 0015536155 scopus 로고
    • Differential effects of cyclophosphamide on the B and T cell compartments of adult mice
    • (1973) J Immunol , vol.110 , pp. 277-282
    • Stockman1    Heim2    South3
  • 53
    • 0017647077 scopus 로고
    • Effect of immunosuppressive drugs on T and B lymphocytes in guinea pigs
    • (1977) Blood , vol.50 , pp. 81-91
    • Winkelstein1
  • 54
    • 0015856856 scopus 로고
    • The effect of cyclophosphamide on leukocyte kinetics and susceptibility to infection in patients with Wegener's granulomatosis
    • (1973) Arthritis Rheum , vol.16 , pp. 657-664
    • Dale1    Fauci2    Wolff3
  • 55
    • 0017162468 scopus 로고
    • Specific acquired immune unresponsiveness to contact allergens with cyclophosphamide in the mouse
    • (1976) Int Arch Allergy , vol.50 , pp. 651-658
    • Maguire1
  • 56
    • 0002204945 scopus 로고
    • Prolongation of homograft survival in mice with single doses of cyclophosphamide
    • (1963) Nature , vol.200 , pp. 84
    • Berenbaum1    Brown2
  • 57
    • 0015046251 scopus 로고
    • The effect of cytotoxic drugs on graft versus host disease in mice
    • (1971) Transplantation , vol.11 , pp. 378-382
    • Owens1    Santos2
  • 59
    • 0014045216 scopus 로고
    • Enhancement of dinitrochlorobenzene (DNCB) contact sensitization by cyclophosphamide in the guinea pig
    • (1967) J Invest Dermatol , vol.48 , pp. 39-43
    • Maguire1    von2
  • 60
    • 0015417297 scopus 로고
    • Functional aspects of the selective depletion of lymphoid tissue by cyclophosphamide
    • (1972) Immunology , vol.23 , pp. 493-501
    • Turk1    Parker2    Poulter3
  • 62
    • 0016206713 scopus 로고
    • Potentiation of T-cell-mediated immunity by selective suppression of antibody formation with cyclophosphamide
    • (1974) J Exp Med , vol.139 , pp. 1529-1539
    • Lagrange1    MacKaness2    Miller3
  • 63
    • 0017689222 scopus 로고
    • Influence of cyclophosphamide on delayed hypersensitivity and acquired cellular resistance to Listeria monocytogenes in the mouse
    • (1977) Immunology , vol.32 , pp. 1027-1032
    • Kerkhaert1    Hofhuis2    Willers3
  • 65
    • 0018257964 scopus 로고
    • Differential cyclophosphamide sensitivity of suppressor and cytotoxic cell precursors
    • (1978) Transplantation , vol.25 , pp. 36-38
    • Ferguson1    Simmons2
  • 66
    • 84915122040 scopus 로고
    • Selective depletion of Ig-bearing lymphocytes by cyclophosphamide depletion in rheumatoid arthritis and systemic lupus erythematosus: Guidelines for dosage
    • (1974) Arthritis Rheum , vol.13 , pp. 754-760
    • Horwitz1
  • 67
    • 0018869708 scopus 로고
    • Activation of human B lymphocytes XII. Differential effects of in vitro cyclophosphamide on human lymphocyte subpopulations involved in B cell activation
    • (1980) Immunology , vol.39 , pp. 391-397
    • Stevenson1    Fauci2
  • 68
    • 0014006226 scopus 로고
    • 19S and 7S antibody production in the cyclophosphamide or methotrexate treated rat
    • (1966) Nature , vol.209 , pp. 622-624
    • Santos1    Owen2
  • 69
  • 70
    • 0014832373 scopus 로고
    • Studies on the induction of immunological paralysis to bovine globulin in adult mice: II. The effect of cyclophosphamide
    • (1970) Immunology , vol.19 , pp. 291-299
    • Kawaguchi1
  • 71
  • 72
    • 0015612398 scopus 로고
    • Further studies on B-lymphocyte suppression in delayed hypersensitivity, indicating a possible mechanism for Jones-Mote hypersensitivity
    • (1973) Immunology , vol.24 , pp. 751-758
    • Turk1    Parker2
  • 74
    • 0016733181 scopus 로고
    • The effect of cyclophosphamide on B and T lymphocytes in patients with connective tissue diseases
    • (1975) Arthritis Rheum , vol.18 , pp. 67-75
    • Hurd1    Guiliano2
  • 75
  • 76
    • 0013872975 scopus 로고
    • Inhibition of the local inflammatory response in man by antimetabolites
    • (1966) Blood , vol.27 , pp. 38-48
    • Hersh1    Wong2    Freireich3
  • 77
    • 0018773931 scopus 로고
    • Induction in vitro of reversible immunosuppression and inhibition of B cell receptor regeneration by defined metabolites of cyclophosphamide
    • (1979) Eur J Immunol , vol.9 , pp. 17-21
    • Shand1    Howard2
  • 78
    • 0018598486 scopus 로고
    • T-suppressor cells sensitive to cyclophosphamide and to its in vitro active derivative 4-hydroperoxycyclophosphamide control the mitogenic response of murine splenic B cells to dextran sulfate. A direct proof for different sensitivities of lymphocyte subsets to cyclophosphamide
    • (1979) J Exp Med , vol.150 , pp. 1571-1576
    • Diamantstein1    Willinger2    Reiman3
  • 79
    • 0018818370 scopus 로고
    • Relative susceptibilities of T cell subsets involved in delayed-type hypersensitivity to sheep red blood cells to the in vitro action of 4-hydroperoxycyclophosphamide
    • (1980) J Immunol , vol.125 , pp. 1104-1108
    • Kaufman1    Hahn2    Diamantstein3
  • 80
    • 0019505298 scopus 로고
    • Direct in vitro evidence for different susceptibilities to 4-hydroperoxycyclophosphamide of antigen-primed T cells regulating humoral and cell-mediated immune responses to sheep erythrocytes: A possible explanation for the inverse action of cyclophosphamide on humoral and cell-mediated immune responses
    • (1981) J Immunol , vol.126 , pp. 1717-1719
    • Diamantstein1    Klos2    Hahn3
  • 81
    • 0020059433 scopus 로고
    • In vitro effects of 4-hydroperoxycyclophosphamide on human immunoregulatory T subset function. I. Selective effects on lymphocyte function in T-B cell collaboration
    • (1982) J Exp Med , vol.155 , pp. 276-290
    • Ozer1    Cowens2    Colvin3
  • 83
    • 0017582644 scopus 로고
    • Effects of cyclophosphamide and of busulfan on spleen colony-forming units and on hematopoietic stroma
    • (1977) Cancer Res , vol.37 , pp. 1205-1209
    • Fried1    Kedo2    Barone3
  • 84
  • 86
    • 0000817026 scopus 로고
    • Cytological study of the effect of cyclophosphamide on the epithelium of the urinary bladder in man
    • (1964) Cancer , vol.17 , pp. 1348-1355
    • Forni1    Koss2    Geller3
  • 87
    • 0013953873 scopus 로고
    • Cyclophosphamide hemorrhagic cystitis
    • (1966) J Urol , vol.96 , pp. 313-316
    • Rubin1    Rubin2
  • 89
    • 0018696672 scopus 로고
    • Bladder complications in patients receiving cyclophosphamide for systemic lupus erythematosus or rheumatoid arthritis
    • (1979) Ann Intern Med , vol.91 , pp. 221-223
    • Plotz1    Klippel2    Decker3
  • 91
    • 0015074932 scopus 로고
    • Cyclophosphamide necrosis of the bladder causing calcification, contracture and reflux: Treated by colocystoplasty
    • (1971) Br J Urol , vol.43 , pp. 324-332
    • Marsh1    Vince2    Pollock3
  • 92
    • 0015219287 scopus 로고
    • Urinary-bladder fibrosis and telangiectarsia associated with long-term cyclophosphamide therapy
    • (1971) N Engl J Med , vol.284 , pp. 290-294
    • Johnson1    Meadows2
  • 95
    • 0018745632 scopus 로고
    • Controlled clinical studies with an antidose against urotoxicity of oxazaphosphorines: preliminary results
    • (1979) Cancer Treat Rep , vol.63 , pp. 501-505
    • Scheef1    Klein2    Brock3
  • 96
    • 0016704280 scopus 로고
    • Carcinoma of the urinary bladder in patients receiving cyclophosphamide
    • (1975) N Engl J Med , vol.293 , pp. 271-273
    • Wall1    Clausen2
  • 97
  • 99
    • 84970823176 scopus 로고
    • Cyclophosphamide and the bladder (letter)
    • (1971) Br Med J , vol.3 , pp. 182
    • Worth1
  • 100
    • 0015965454 scopus 로고
    • Effect of a single dose of cyclophosphamide: V. Protective effect of diversion of the urinary stream on dog bladder
    • (1974) Lab Invest , vol.30 , pp. 43-47
    • Bellin1    Cherry2    Koss3
  • 102
    • 0015502394 scopus 로고
    • Sterility and testicular atrophy related to cyclophosphamide therapy
    • (1972) Lancet , vol.1 , pp. 568-569
    • Fairley1    Barrie2    Johnson3
  • 104
    • 0015234150 scopus 로고
    • Alkylating agents and human spermatogenesis
    • (1971) JAMA , vol.217 , pp. 1662-1665
    • Miller1
  • 106
    • 84915114370 scopus 로고
    • Leydig cell dysfunction in male patients with Hodgkins disease receiving chemotherapy (abstract)
    • (1978) Clin Res , vol.26 , pp. 437A
    • Jacobson1    Sagel2    Distiller3
  • 109
    • 0015936293 scopus 로고
    • Reversible drug-induced sterility in a patient with acute leukemia
    • (1973) JAMA , vol.223 , pp. 1490-1491
    • Hinkes1    Plotkin2
  • 116
    • 0016151017 scopus 로고
    • Chromosome abnormalities from cyclophosphamide therapy in rheumatoid arthritis and progressive systemic sclerosis (scleroderma)
    • (1974) Arthritis Rheum , vol.17 , pp. 375-382
    • Tolchin1    Winkelstein2    Rodnan3
  • 117
    • 0001199992 scopus 로고
    • Congenital anomalies probably induced by cyclophosphamide
    • (1964) JAMA , vol.188 , pp. 423-426
    • Greenberg1    Tanaka2
  • 119
    • 0017121727 scopus 로고
    • Genetic effects of cyclophosphamide, ifosfamide and trofosfamide
    • (1976) Mutat Res , vol.32 , pp. 331-360
    • Mohn1    Ellenberger2
  • 120
    • 0017363556 scopus 로고
    • Experimental studies on the genesis of limb malformations produced in chicken embryos with nitrogen mustard
    • (1977) Birth Defects , vol.13 , pp. 155-177
    • Salzberger1
  • 121
    • 0015042494 scopus 로고
    • Zur Frage der carcinogen Wirkung von Krebs-Chemotherapeutica and chemischen Immunosuppressiva
    • (1971) Arzneim-Forsch , vol.21 , pp. 435-443
    • Brock1    Schneider2
  • 122
    • 0014333813 scopus 로고
    • Immunosuppression by cyclophosphamide in NZB x NZW mice with lupus nephritis
    • (1968) Blood , vol.32 , pp. 436-444
    • Casey1
  • 123
    • 0016477799 scopus 로고
    • Influence of cyclophosphamide and other immunosuppressive drugs on immune disorders and neoplasia in NZB/NZW mice
    • (1975) Arthritis Rheum , vol.18 , pp. 145-152
    • Hahn1    Knotts2    Ng3
  • 124
    • 28444477819 scopus 로고
    • Intracerebral lymphoma in a patient with central nervous system lupus on cyclophosphamide
    • (1974) J Rheumatol , vol.1 , pp. 282-286
    • Uhl1    Williams2    Arnett3
  • 127
    • 0015592898 scopus 로고
    • Acute leukemia complicating metastatic breast cancer
    • (1973) Cancer , vol.31 , pp. 543-546
    • Davis1    Prout2    McKenna3
  • 128
    • 0020473048 scopus 로고
    • The comparative incidence of malignant disease in rheumatoid arthritics exposed to different treatment regimens
    • (1982) Ann Rheum Dis , vol.41 , pp. 12-17
    • Hazleman1
  • 129
    • 0011324094 scopus 로고
    • An association between the rheumatic diseases and the reticuloses
    • (1964) Ann Rheum Dis , vol.23 , pp. 480-484
    • Lea1
  • 130
    • 0016216125 scopus 로고
    • Alopecia activity of cyclophosphamide metabolites and related compounds in sheep
    • (1974) Cancer Res , vol.34 , pp. 2596-2598
    • Feil1    Lamoureux2
  • 131
    • 84965265877 scopus 로고
    • Alopecia and cytotoxic drugs (letter)
    • (1966) Br Med J , vol.2 , pp. 1138
    • Hennessy1
  • 133
    • 84984296961 scopus 로고
    • High dose cyclophosphamide therapy for malignant disease Toxicity tumor response and the effects of stored autologous marrow
    • (1972) Cancer , vol.29 , pp. 357-365
    • Buckner1    Rudolph2    Fefer3
  • 135
    • 0016257397 scopus 로고
    • Cardiac and pulmonary effects of high doses of cyclophosphamide and isophosphamide
    • (1974) Cancer Res , pp. 1586-1591
    • O'Connell1    Berenbaum2
  • 138
    • 0018835822 scopus 로고
    • Cytotoxic drug-induced pulmonary disease
    • (1980) Am J Med , vol.68 , pp. 259-266
    • Weiss1    Muggia2
  • 139
    • 0017812760 scopus 로고
    • Late onset pulmonary fibrosis and chest deformity in two children treated with cyclophosphamide
    • (1978) J Pediatr , vol.92 , pp. 443-446
    • Alvarado1    Boat2    Newman3
  • 141
    • 0013849356 scopus 로고
    • Untersuchungen uber die Kombinierte cytostatische therapy: Der Einflub von Cyclophosphamid und Mitomycin C aufden Cortisonabbau in der Leber
    • (1965) Klin Wochenschr , vol.43 , pp. 1220-1223
    • Schmidt1    Lutzmann2
  • 143
    • 0015506783 scopus 로고
    • 144C] cyclophosphamide and its radioactive metabolites in rats pretreated with prednisolone
    • (1972) Biochem Pharmacol , vol.21 , pp. 272-276
    • Hanasono1    Fischer2
  • 146
    • 0014576495 scopus 로고
    • Response of a “resistant” plasmocytoma to alkylating agents and x-ray in combination with the “exercision repair inhibitors” caffeine and chloroquine
    • 9th ed
    • (1969) Proc Soc Exp Biol Med , vol.131 , pp. 1413-1416
    • Gaudin1    Yielding2
  • 149
    • 0015849244 scopus 로고
    • Water intoxication in man after cyclophosphamide therapy: Time course and relation to drug activation
    • (1973) Ann Intern Med , vol.78 , pp. 861-869
    • DeFronzo1    Braine2    Colvin3
  • 150
    • 0020160795 scopus 로고
    • Cyclophosphamide hepatotoxicity in a patient with systemic lupus erythematosus
    • (1982) Ann Intern Med , vol.97 , pp. 62-63
    • Bacon1    Rosenberg2
  • 151
    • 84967899994 scopus 로고
    • Massive hepatic necrosis after cyclophosphamide (letter)
    • (1970) BMJ , vol.3 , pp. 588
    • Aubery1
  • 153
    • 0016683420 scopus 로고
    • Immediate cerebral symptoms during rapid intravenous infusion of cyclophosphamide (NSC-26271)
    • (1975) Cancer Chemother Rep , vol.59 , pp. 441-442
    • Tashima1
  • 155
    • 0017615697 scopus 로고
    • Possible anaphylatic reaction to intravenous cyclophosphamide Report of a case
    • (1977) JAMA , vol.237 , pp. 475
    • Karchmer1    Hansen2
  • 156
    • 0017117823 scopus 로고
    • Generalized urticaria to cyclophosphamide. Type I hypersensitivity to an immunosuppressive agent
    • (1976) J Allergy Clin Immunol , vol.58 , pp. 160-171
    • Lakin1    Cahill2
  • 157
    • 0015462702 scopus 로고
    • Oropharyngeal sensation associated with rapid intravenous administration of cyclophosphamide (NSC-26271)
    • (1972) Cancer Chemother Rep , vol.56 , pp. 779-780
    • Arena1
  • 158
    • 0016839941 scopus 로고
    • Cyclophosphamideinduced nail pigmentation (letter)
    • (1975) Lancet , vol.2 , pp. 548-549
    • Shah1    Rao2    Patel3
  • 161
    • 0018361922 scopus 로고
    • A new therapeutic strategy in systemic vasculitis?
    • (1979) N Engl J Med , vol.301 , pp. 266-267
    • Zweiman1
  • 165
    • 0016259448 scopus 로고
    • Comparison of azathioprine, cyclophosphamide, and gold in treatment of rheumatoid arthritis
    • (1974) Br Med J , vol.3 , pp. 763-766
    • Currey1    Harris2    Manson3
  • 166
    • 0014958956 scopus 로고
    • A controlled trial of cyclophosphamide in rheumatoid arthritis
    • (1970) N Engl J Med , vol.283 , pp. 883-889
  • 167
  • 169
    • 0016130965 scopus 로고
    • A double-blind comparative trial of cyclophosphamide in rheumatoid arthritis (abstract)
    • (1974) Ann Rheum Dis , vol.33 , pp. 574
    • Gumpel1    Hall2    Ansell3
  • 172
    • 0018773733 scopus 로고
    • A combined clinical and immunological assessment of four cyclophosphamide regimes in rheumatoid arthritis
    • (1979) Agents Actions , vol.9 , pp. 97-102
    • Hall1    Bird2    Ring3
  • 175
    • 0018888663 scopus 로고
    • Rheumatoid vasculitis: Effect of cyclophosphamide on the clinical course and levels of circulating immune complexes
    • (1980) Ann Intern Med , vol.93 , pp. 407-413
    • Abel1    Andrews2    Cunningham3
  • 178
    • 0015936543 scopus 로고
    • Cyclophosphamide in the treatment of systemic lupus erythematosus: 7 years experience
    • (1973) Br Med J , vol.2 , pp. 450-452
    • Feng1    Jayaratnam2    Tock3
  • 179
    • 0014875111 scopus 로고
    • Cyclophosphamide in systemic lupus erythematosus
    • (1970) Ann Rheum Dis , vol.29 , pp. 673-676
    • Hadidi1
  • 180
    • 0014006316 scopus 로고
    • Cyclophosphamide in the treatment of systemic lupus erythematosus
    • (1966) BMJ , vol.1 , pp. 333-335
    • Seah1    Wong2    Chew3
  • 182
    • 84915119380 scopus 로고
    • Immunosuppressive therapy in connective tissue diseases other than rheumatoid arthritis
    • (1974) J Rheumatol , vol.1 , pp. 374-391
    • Fraga1    Mintz2    Orozco3
  • 184
    • 0016309973 scopus 로고
    • A double-blind controlled trial comparing cyclophosphamide, azathioprine, and placebo in the treatment of lupus glomerulonephritis
    • (1974) Arthritis Rheum , vol.17 , pp. 1923-1937
    • Steinberg1    Decker2
  • 187
    • 0018118982 scopus 로고
    • Treatment of diffuse proliferative lupus nephritis with prednisone and combined prednisone and cyclophosphamide
    • (1978) N Engl J Med , vol.299 , pp. 1151-1155
    • Donadio1    Holley2    Ferguson3
  • 188
    • 0018648075 scopus 로고
    • Comparisons of chlorambucil, azathioprine or cyclophosphamide in the treatment of lupus nephritis
    • (1979) Br J Dermatol , vol.100 , pp. 113-125
    • Sabbour1    Osman2
  • 191
    • 0019470332 scopus 로고
    • Systemic lupus erythematosus-survival patterns: Experience with 609 patients
    • (1981) JAMA , vol.245 , pp. 934-938
    • Wallace1    Podell2    Weiner3
  • 192
    • 0019994604 scopus 로고
    • A multicenter study of outcome in systemic lupus erythematosus: I entry variables as predictors of prognosis
    • (1982) Arthritis Rheum , vol.25 , pp. 601-611
    • Ginzler1    Diamond2    Weiner3
  • 197
    • 0015764397 scopus 로고
    • Wegener's granulomatosis: Studies in eighteen patients and a review of the literature
    • (1973) Medicine , vol.52 , pp. 535-561
    • Fauci1    Wolff2
  • 200
    • 0017603375 scopus 로고
    • Wegener's granulomatosis, lymphomatoid granulomatosis and benign lymphocytic angiitis and granulomatosis of lung: Recognition and treatment
    • (1977) Ann Intern Med , vol.87 , pp. 691-699
    • Israel1    Patchefsky2    Saldana3
  • 204
    • 0019956263 scopus 로고
    • Lymphomatoid granulomatosis: Prospective clinical and therapeutic experience over 10 years
    • (1982) N Engl J Med , vol.306 , pp. 68-74
    • Fauci1    Haynes2    Costa3
  • 205
    • 0020054508 scopus 로고
    • Lymphomatoid granulomatosis: Clinicopathological study of four cases and literature review
    • (1982) Medicine , vol.61 , pp. 1-12
    • Patton1    Lynch2
  • 206
  • 207
    • 0018090884 scopus 로고
    • Cyclophosphamide-induced remission in advanced polyarteritis nodosa
    • (1978) Am J Med , vol.64 , pp. 890-894
    • Fauci1    Doppman2    Wolff3
  • 208
    • 0018607902 scopus 로고
    • Immunosuppressive and corticosteroid therapy of polyarteritis nodosa
    • (1979) Am J Med , vol.67 , pp. 941-947
    • Leib1    Restivo2    Paulus3
  • 209
    • 0018864167 scopus 로고
    • Onset of polyarteritis nodosa during allergic hyposensitization treatment
    • (1980) Am J Med , vol.68 , pp. 479-485
    • Phanuphak1    Kohler2
  • 212
    • 0020083680 scopus 로고
    • Chronic recurrent small-vessel cutaneous vasculitis: Clinical experience in 13 patients
    • (1982) JAMA , vol.247 , pp. 1994-1998
    • Cupps1    Springer2    Fauci3
  • 214
    • 0017640201 scopus 로고
    • A computerassisted analysis of 153 patients with polymyositis and dermatomyositis
    • (1977) Medicine , vol.56 , pp. 255-286
    • Bohan1    Peter2    Bowman3
  • 215
    • 0018834704 scopus 로고
    • Immunosuppressive agents in corticosteroid-refractory childhood dermatonyositis
    • (1980) Neurology , vol.30 , pp. 286-291
    • Niakan1    Pitner2    Whitaker3
  • 217
    • 0019465902 scopus 로고
    • Plasmapheresis in idiopathic inflammatory myopathy: Experience with 35 patients
    • (1981) Arch Neurol , vol.38 , pp. 544-552
    • Dau1
  • 219
  • 220
    • 0018934508 scopus 로고
    • Mixed cryoglobulinemia: Clinical aspects and long-term follow-up of 40 patients
    • (1980) Am J Med , vol.69 , pp. 287-308
    • Gorevic1    Kassab2    Levo3
  • 221
    • 0019440269 scopus 로고
    • The effect of combinatiom therapy (steroids, immunosuppressives, and plasmapheresis) on 5 mixed cryoglobulinemia patients with renal, neurologic, and vascular involvement
    • (1981) Arthritis Rheum , vol.24 , pp. 1121-1127
    • Geltner1    Kohn2    Gorevic3
  • 223
  • 224
    • 0018614889 scopus 로고
    • Use of combined plasmapheresis and immunosuppression in the treatment of Goodpasture's syndrome
    • 9th ed
    • (1979) Mayo Clin Proc , vol.54 , pp. 714-720
    • Erickson1    Kurtz2    Donadio3
  • 226
    • 0014009185 scopus 로고
    • Immunosuppressive therapy in steroid-resistant proliferative glomerulonephritis accompanied by nephrotic syndrome
    • (1966) Br Med J , vol.2 , pp. 853-860
    • White1    Cameron2    Trounce3
  • 227
    • 0013973282 scopus 로고
    • Cytotoxic drugs in steroid resistant renal disease. Alkylating and antimetabolic agents in the treatment of nephrotic syndrome, lupus nephritis, chronic glomerulonephritis, and purpura nephritis in children
    • (1966) Am J Dis Child , vol.112 , pp. 448-458
    • Grupe1    Heymann2


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