Mechanisms of inhibition by mevinolin (mk 803) of microsome-bound radish and of partially purified yeast hmg-coa reductase (ec.l.1.1.34)

Zeitschrift fur Naturforschung - Section C Journal of Biosciences

Volumn 38, Issue 3-4, 1983, Pages 212-219

  Bach, Th J ^a   Lichtenthaler, H K ^b  

^a UNIVERSITY OF KARLSRUHE   (Germany)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

Enzyme Inhibition; HMG CoA Reductase; Isoprenoid Biosynthesis; Mevalonate; Mevinolin

Indexed keywords

HYDROXYMETHYLGLUTARYL COA REDUCTASE INHIBITORS; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; MEVINOLIN; NAPHTHALENE DERIVATIVE;

ANIMAL; ARTICLE; ASPERGILLUS NIGER; COMPARATIVE STUDY; ENZYMOLOGY; KINETICS; LIVER MICROSOME; MICROSOME; PLANT; RAT; SPECIES DIFFERENCE; STRUCTURE ACTIVITY RELATION;

ANIMAL; ASPERGILLUS NIGER; COMPARATIVE STUDY; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; KINETICS; LOVASTATIN; MICROSOMES; MICROSOMES, LIVER; NAPHTHALENES; PLANTS; RATS; SPECIES SPECIFICITY; STRUCTURE-ACTIVITY RELATIONSHIP; SUPPORT, NON-U.S. GOV'T;

EID: 0020726330     PISSN: 09395075     EISSN: 18657125     Source Type: Journal    
DOI: 10.1515/znc-1983-3-410     Document Type: Article

References (70)

1. A. W. Alberts, J. Chen, G. Kuron, V. Hunt, J. Huff, C Hoffman, J. Rothrock, M. Lopez, H. Joshua, E. Harris, A. Patchett, R. Monagan, S. Currie, E. Stapley, G. Albers-Schonberg, O. Hensens, J. Hirsh-field, K. Hoogsteen, J. Liesch, and J. Springer, Proc. Natl. Acad. Sci. USA 77, 3957 (1980).
2. D. Kritchevsky, S. A. Tepper, and D. M. Klurfeld, Pharmacol. Res. Commun. 13,921 (1981).
3. J. A. Tobert, G. Hitzenberger, W. R. Kukovetz, I. B. Holmes, and K. H. Jones, Atherosclerosis 41, 61 (1982
4. J. A. Tobert, G. D. Bell, J. Birtwell, I. James, W. R. Kukovetz, J. S. Pryor, A. Buntix, I. B. Holmes, Y.-S. Chao, and J. A. Bolognese, J. Clin. Invest. 69, 913 (1982b).
5. A. G. Brown, T. C. Smale, T. J. King, R. Hasenkamp, and R. H. Thompson, J. Chem. Soc. Perkin I 1976, 1165.
6. A. Endo, M. Kuroda, and Y. Tsujita, J. Antibiotics 29, 1346 (1976).
7. G. Albers-Schonberg, H. Joshua, M. Lopez, O. HenSens, J. Springer, J. Chen, S. Ostrove, C. Hoffman, A. Alberts, and A. Patchett, J. Antibiotics 34, 507 (1981).
8. Y. K. Tonylam, V. P. Gullo, R. T. Goegelman, D. Jorn, L. Huang, C. DeRiso, R. L. Monaghan, and I. Putter, J. Antibiotics 34, 614 (1981).
9. A. Endo, M. Kuroda, and K. Tanzawa, FEBS Lett. 72, 323 (1976).
10. K. Tanzawa and A. Endo, Eur. J. Biochem. 98, 195(1979).
11. A. Endo, J. Antibiotics 32, 852 (1979).
12. A. Endo, J. Antibiotics 33, 334 (1980).
13. A. Endo, Trends Biochem. Sci. 6, 10 (1981
14. A. Endo, Meth. Enzymol. 72, 684 (1981
15. M. S. Brown, J. R. Faust, J. L. Goldstein, I. Kaneko, and A. Endo, J. Biol. Chem. 253, 1121 (1978).
16. I. Kaneko, Y. Hazama-Shimada, and A. Endo, Eur. J. Biochem. 87, 313 (1978).
17. W. R. Bench, T. S. Ingebritsen, and E. R. Diller, Biochem. Biophys. Res. Commun. 82, 247 (1978).
18. J. R. Faust, J. L. Goldstein, and M. S. Brown, Arch. Biochem. Biophys. 192, 86 (1979).
19. V. Quesney-Huneeus, M. H. Wiley, and M. D. Siperstein, Proc. Natl. Acad. Sci. USA 76, 5056 (1979).
20. V. Quesney-Huneeus, M. H. Wiley, and M. D. Siperstein, Proc. Natl. Acad. Sci. USA 77, 5842 (1980).
21. A. M. D. Nambudiri, S. Ranganathan, and H. Rudney, J. Biol. Chem. 255, 5894 (1980).
22. M. S. Brown and J. L. Goldstein, J. Lipid Res. 21, 505 (1980).
23. P. A. Edwards, D. Lemongello, J. Kane, I. Shechter, and A. M. Fogelman, J. Biol. Chem. 255, 3715 (1980).
24. J. R. Faust, M. S. Brown, and J. L. Goldstein, J. Biol. Chem. 255, 6546 (1980).
25. R. Fears, Biochem. J. 199, 1 (1981).
26. D. K. Chin, K. L. Luskey, R. G. W. Anderson, J. R. Faust, J. L. Goldstein, and M. S. Brown, Proc. Natl. Acad. Sci. USA 79, 1185 (1982).
27. T. Kita, M. S. Brown, and J. L. Goldstein, J. Clin. Invest. 66, 1094 (1980).
28. D. H. Rogers and H. Rudney, J. Biol. Chem. 257, 10650 (1982).
29. R. D. Tanaka, P. A. Edwards, S.-F. Lan, E. M. Knöppel, and A. M. Fogelman, J. Lipid Res. 23, 1026 (1982).
30. W. E. Brown and V. W. Rodnell, in: Dehydrogenases Requiring Nicotinamide Coenzymes (J. Jeffery, ed.). pp. 232-272, Birkhäuser Verlag, Basel-Boston-Stuttgart 1980.
31. T. J. Bach, Karlsr. Beitr. Pflanzenphysiol. 10, 1-219, (ISSN 0173-3133) (1981).
32. G. Schroepfer, Jr., Annu. Rev. Biochem. 50, 585 (1981).
33. N. Qureshi and J. W. Porter, in: Biosynthesis of Isoprenoid Compounds, Vol. I (J. W. Porter, S. L. Spurgeon, eds.), pp. 47-94, Wiley, New York 1981.
34. R. E. Dugan, in: Biosynthesis of Isoprenoid Compounds, Vol. I (J. W. Porter, S. L. Spurgeon eds.), pp. 95-159, J. Wiley, New York 1981.
35. S. R. Panini, D. H. Rogers, and H. Rudney, in: Regulation of HMG-CoA Reductase (B. Preiss, ed.), Academic Press, New York, NY (in press) (1983).
36. D. H. Rogers, S. R. Panini, and H. Rudney, in: Monographs on Enzyme Biology: HMG-CoA Reductase (J. R. Sabine, ed.), CRC Press, Boca Raton, PL. (in press) 1983.
37. J. D. Brooker and D. W. Russell, Arch. Biochem. Biophys. 167, 723 (1975).
38. J. D. Brooker and D. W. Russell, Arch. Biochem. Biophys. 167, 730 (1975).
39. H. Suzuki, I. Uritani, and K. Oba, Physiol. Plant. Pathol. 7, 265 (1975).
40. T. J. Bach, H. K. Lichtenthaler, and J. Rétey, Abstracts of the Symposium on –Lipids and Lipid Polymers in Higher Plants—, Botanical Institute of Karlsruhe, p. 96 (1976).
41. H. Suzuki and I. Uritani, Plant and Cell Physiol. 17, 691 (1976).
42. H. Suzuki and I. Uritani, Plant and Cell. Physiol. 18, 485 (1977).
43. K. H. Grumbach and T. J. Bach, Z. Naturforsch. 34c, 941 (1979).
44. R. Ito, K. Oba, and I. Uritani, Plant and Cell Physiol. 20, 867 (1979).
45. T. J. Bach, H. K. Lichtenthaler, and J. Rétey, in: Biogenesis and Function of Plant Lipids (P. Mazliak, P. Benveniste, C. Costes, and R. Douce, eds.), pp. 355-362, Elsevier, Amsterdam, ISBN 0-86689-012-2 (1980).
46. D. W. Russell and H. Davidson, Biochem. Biophys. Res. Commun. 104, 1537 (1982).
47. T. J. Bach and H. K. Lichtenthaler, Abstracts 3rd Meeting –Pflanzliche Lipide—, University of Ulm, F.R.G., October 2, p. 20 (1981).
48. T. J. Bach and H. K. Lichtenthaler, in: Biochemistry and Metabolism of Plant Lipids, pp. 515-522 (J. F.G. M. Wintermans and P. J. C. Kuiper, eds.), Elsevier, Amsterdam 1982.
49. T. J. Bach and H. K. Lichtenthaler, Z. Naturforsch. 37c, 46 (1982).
50. T. J. Bach and H. K. Lichtenthaler, Naturwissenschaften 69, 242 (1982).
51. J. Huber, S. Latzin, and B. Ham recht, Hoppe Seyler's Z. Physiol. Chemie 354, 1645 (1973).
52. H.-J. Lee and I. B. Wilson, Biochim. Biophys. Acta 242,519 (1971).
53. N. Glick, A. D. Landman, and B. D. Roufogalis, Trends Biochem. Sci. 4, N82 (1979).
54. M. E. Kirtley and H. Rudney, Biochemistry 6, 230 (1967).
55. J. Rétey, E. v. Stetten, U. Coy, and F. Lynen, Eur. J. Biochem. 15, 72 (1970).
56. A. Bensadoun and D. Weinstein, Anal. Biochem. 70, 241 (1976).
57. T. J. Bach and H. K. Lichtenthaler, Abstracts of the –2. Arbeitstagung Pflanzliche Lipide—, Universität zu Köln, pp. 40-41 (1979).
58. M. Kuroda, Y. Hazama-Shimada, and A. Endo, Biochim. Biophys. Acta 486, 254 (1977).
59. K. Tanzawa, M. Kuroda, and A. Endo, Biochim. Biophys. Acta 488, 97 (1977).
60. N. Qureshi, R. E. Dugan, W. W. Cleland, and J. W. Porter, Biochemistry 15,4191 (1976).
61. A. Tan-Wilson and G. B. Kohlhaw, Biochem. Biophys. Res. Commun. 85, 70 (1978).
62. H. F. Gilbert and M. D. Stewart, J. Biol. Chem. 256, 1782 (1981).
63. T.-G. Nguyen, H. Aigner, and H. Eggerer, FEBS Lett. 128, 145 (1981).
64. H. M. Miziorko, P. R. Kramer, and J. A. Kulkoski, J. Biol. Chem. 257, 2842 (1982).
65. T. J. Bach and H. K. Lichtenthaler, Abstracts of the symposium –Recent Advances in the Biogenesis and Function of Plant Lipids—, p. 26, Paris, June 1980.
66. K. J. Lendzian, Planta 148, 1-6 (1980).
67. D. H. Rogers and H. Rudney, J. Biol. Chem. 257, 10650 (1982).
68. A. Holmgren, Trends Biochem. Sci. 6, 26 (1981).
69. D. J. Monger, W. A. Lim, F. J. Kezdy, and J. H. Law, Biochem. Biophys. Res. Commun. 105, 1374 (1982).
70. M. Tada and M. Shiroishi, Plant and Cell Physiol. 231,615 (1982).