The "LY-1 B" cell subpopulation in normal, immunodefective, and autoimmune mice

Journal of Experimental Medicine

Volumn 157, Issue 1, 1983, Pages 202-218

  Hayakawa, Kyoko ^a   Hardy, Richard R ^a,b   Parks, David R ^a   Herzenberg, Leonore A ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b AMERICAN CANCER SOCIETY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOIMMUNITY; B LYMPHOCYTE; ETIOLOGY; HEREDITY; IMMUNE DEFICIENCY; LYB ANTIGEN; LYMPHATIC SYSTEM; MOUSE; NONHUMAN;

AGE FACTORS; ANIMAL; ANTIGENS, LY; ANTIGENS, SURFACE; AUTOIMMUNE DISEASES; B-LYMPHOCYTES; CELL SEPARATION; FLOW CYTOMETRY; IMMUNOGLOBULIN M; IMMUNOGLOBULINS, SURFACE; IMMUNOLOGIC DEFICIENCY SYNDROMES; MICE; MICE, INBRED NZB; SPLEEN; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0020681403     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.157.1.202     Document Type: Article

References (42)

1. Boyse, E. A., M. Miyazawa, T. Aoki, and L. J. Old. 1968. Ly-A and Ly-B: two systems of lymphocyte isoantigens in the mouse. Proc. R. Soc. Land. B Biol. Sci. 170: 175.
2. Boyse, E. A., K. Itakura, E. Stockert, C. A. Iritani, and M. Miura. 1971. Lyc: a third locus specifying alloantigens expressed only on thymocytes and lymphocytes. Transplantation (Baltimore). 11: 351.
3. Cantor, H., and E. A. Boyse. 1975. Functional subclasses of T lymphocytes bearing different Ly antigens. I. The generation of functionally distinct T-cell subclasses in a differentiation process independent of antigen. J. Exp. Med. 141: 1376.
4. Cantor, H., and E. A. Boyse. 1975. Functional subclasses of T lymphocytes bearing different Ly antigens. II. Cooperation between subclasses of Lyt cells in the generation of killer activity. J Exp. Med. 141: 1390.
5. Cantor, H., F. W. Shen, and E. A. Boyse. 1976. Separation of helper from suppressor T cells expressing Ly components. II. Activation by antigen: after immunization, antigen-specific suppressor and helper activities are mediated by distinct T-cell subclasses. J. Exp. Med. 143: 1391.
6. Beverley, P. C. L., J. Woody, M. Dunkely, M. Feldman, and I. F. C. McKenzie. 1976. Separation of suppressor and killer T cells by surface phenotype. Nature (Lond.). 262: 495.
7. Lanier, L. L., N. L. Warner, J. A. Ledbetter, and L. A. Herzenberg. 1981. Expression of Lyt-1 antigen on certain murine B cell lymphomas. J. Exp. Med. 153: 998.
8. Ledbetter, J. A., R. V. Rouse, H. S. Micklem, and L. A. Herzenberg. 1980. T cell subsets defined by expression of Lyt-1,2,3, and Thy-1 antigens: two-parameter immunofluorescence and cytotoxicity analysis with monoclonal antibodies modifies current views. J. Exp. Med. 152: 280.
9. Haaijman, J. J., H. S. Micklem, J. A. Ledbetter, J. L. Dangl, L. A. Herzenberg, and L. A. Herzenberg. 1981. T cell ontogeny. Organ location of maturing populations as defined by surface antigen markers is similar in neonates and adults. J. Exp. Med. 153: 605.
10. Hardy, R. R., K. Hayakawa, J. Haaijman, and L. A. Herzenberg. 1983. B cell subpopulations identifiable by two-color fluorescence analysis using a dual-laser FACS. Ann. N. Y. Acad. Sci. In press.
11. Manohar, V., E. Brown, W. M. Leiserson, and T. M. Chused. 1982. Expression of Lyt-1 by a subset of B lymphocytes. J. Immunol. 129: 532.
12. Cantor, H., L. McVay-Boudreau, J. Hugenberger, K. Naidorf, F. W. Shen, and R. K. Gershon. 1978. Immunoregulatory circuits among T-cell sets. II. Physiologic role of feedback inhibition in vivo: absence in NZB mice. J. Exp. Med. 147: 1116.
13. Wang, C. Y., R. A. Good, P. Ammirato, G. Dymbort, and R. L. Evans. 1980. Identification of a p69/70 complex expressed on human T cells sharing determinants with B-type chronic lymphocytic leukemia cells. J. Exp. Med. 151: 1539.
14. Ledbetter, J. A., R. L. Evans, M. Lipinski, C. Cunningham-Rundles, R. A. Good, and L. A. Herzenberg. 1981. Evolutionary conservation of surface molecules that distinguish T lymphocyte helper/inducer and cytotoxic/suppressor subpopulations in mouse and man. J. Exp. Med. 153: 310.
15. Caligaris-Cappio, F., M. Gobbi, M. Bofill, and G. Janossy. 1982. Infrequent normal B lymphocytes express features of B-chronic lymphocytic leukemia. J. Exp. Med. 155: 623.
16. Okumura, K., K. Hayakawa, and T. Tada. 1982. Cell-to-cell interaction controlled by immunoglobulin (Ig) genes: role of Thy-1-, Lyt-l-f-, Ig+ (B’) cell in allotype-restricted antibody formation. J. Exp. Med. 156: 443.
17. Hardy, R. R., K. Hayakawa, J. Haaijman, L. A. Herzenberg, and L. A. Herzenberg. 1982. B cell subpopulations identified by two-color fluorescence analysis. Nature (Land.). 297: 589.
18. Ledbetter, J. A., and L. A. Herzenberg. 1979. Xenogeneic monoclonal antibodies to mouse lymphoid differentiation antigens. Immunol. Rev. 47: 63.
19. Lanier, L. L., N. L. Warner, J. A. Ledbetter, and L. A. Herzenberg. 1981. Quantitative immunofluorescence analysis of surface phenotypes of murine B cell lymphomas and plasmacytomas with monoclonal antibodies. J. Immunol. 127: 1691.
20. Kincade, P. W., G. Lee, L. Sun, and T. Watanabe. 1981. Monoclonal rat antibodies to murine IgM determinants. J. Immunol. Methods. 42: 17.
21. Eckhardt, L. A., and L. A. Herzenberg. 1980. Monoclonal antibodies to ThB detect close linkage of Ly-6 and a gene regulating ThB expression. Immunogenetics. 11: 275.
22. Oi, V. T, P. P. Jones, J. W. Goding, L. A. Herzenberg, and L. A. Herzenberg. 1978. Properties of monoclonal antibodies to mouse Ig allotypes, H-2 and la antigens. Curr. Top. Microbiol. Immunol. 81: 115.
23. Kappler, J. W., B. Skidmore, J. White, and P. Marrack. 1981. Antigen-inducible, H-2 restricted, interleukin-2-producing T cell hybridomas. Lack of independent antigen and H-2 recognition. J. Exp. Med. 153: 1198.
24. Tada, N., S. Kimura, Y. Liu, B. A. Taylor, and U. Hammerling. 1981. Ly-ml9: the Lyb-2 region of mouse chromosome 4 controls a new surface alloantigen. Immunogenetics. 13: 539.
25. Kimura, S., N. Tada, E. Nakayama, Y. Liu, and U. Hammerling. 1981. A new mouse cell-surface antigen (Ly-m20) controlled by a gene linked to Mis locus and defined by monoclonal antibodies. Immunogenetics. 14: 3.
26. Goding J. 1976. Conjugation of antibodies with fluorochromes. Modification to standard methods. J. Immunol. Methods. 13: 215.
27. Bayer, E. A., and M. Wilcheck. 1978. The avidin-biotin complex as a tool in molecular biology. Trends Biochem. Set. 3: N257.
28. Yeh, C.-J. G., B.-L. Hsi, and W. P. Faulk. 1981. Propidium iodide as a nuclear marker in immunofluorescence. II. Use with cellular identification and viability studies. J. Immunol. Methods. 43: 269.
29. Parks, D. R., R. R. Hardy, and L. A. Herzenberg. 1982. Dual Immunofluorescence-new frontiers in cell analysis and sorting. Immunol. Today. In press.
30. Cunningham, A. J., and A. Szenberg. 1968. Further improvements in the plaque technique for detecting single antibody-forming cells. Immunology. 14: 599.
31. Tsu, T. T., and L. A. Herzenberg. 1980. Solid-phase radioimmune assays. In Selected Methods in Cellular Immunology. B. B. Mishell, and S. M. Shiigi, editors. W. H. Freeman and Co., San Francisco. 373.
32. Murphy, E. D., and J. B. Roths. 1978. Autoimmunity and lymphoproliferation: induction by mutant gene lpr, and acceleration by a male-associated factor in strain BXSB mice. In Genetic Control of Autoimmune Disease. N. R. Rose, P. E. Bigazzi, and N. L. Warner, editors. Elsevier/North-Holland, Inc. New York. 207.
33. Scher, I., A. D. Steinberg, A. K. Berning, and W. E. Paul. 1975. X-linked B-lymphocyte immune defect in CBA/N mice. II. Studies of the mechanisms underlying the immune defect. J. Exp. Med. 147: 637.
34. Chused, T. M., H. M. Moutsopoulos, S. O. Sharrow, C. T. Hansen, and H. C. Morse, III. 1978. Mechanism of autoimmune disease in New Zealand black mice. In Genetic Control of Autoimmune Disease. N. R. Rose, P. E. Bigazzi, and N. L. Warner, editors. Elsevier/ North-Holland, Inc. New York. 177.
35. Manny, N., S. K. Datta, and R. S. Schwartz. 1979. Synthesis of IgM by cells of NZB and SWR mice and their crosses. J. Immunol. 122: 1220.
36. Steinberg, A. D., D. P. Huston, J. D. Taurog, J. S. Cowdery, and E. S. Raveche. 1981. The cellular and genetic basis of murine lupus. Immunol. Rev. 55: 121.
37. Theofilopoulous, A. N., D. L. Shawler, R. S. Balderas, J. H. Elder, D. H. Katz, and F. J. Dixon. 1980. Splenic immunoglobulin-secreting cells and their regulation in autoimmune mice. J. Exp. Med. 151: 446.
38. Taurog, J. D., E. S. Raveche, P. A. Smathers, L. H. Glimcher, D. P. Huston, and A. D. Steinberg. 1981. T cell abnormalities in NZB mice occur independently of autoantibody production. J Exp. Med. 153: 221.
39. Cohen, P., M. Ziff, and E. S. Vitetta. 1978. Characterization of a B cell defect in the NZB mouse manifested by an increased ratio of surface IgM to IgD. J. Immunol. 121: 973.
40. Playfair, J. H. L., and E. Purves. 1971. Separate thymus dependent and thymus independent antibody forming cell precursors. Nat. New Biol. 231: 149.
41. Jennings, J. J., and M. B. Rittenberg. 1976. Evidence for separate subpopulations of B cells responding to T-independent and T-dependent antigens. J. Immunol. 117: 1749.
42. Izui, S., P. J. McConahey, and F. J. Dixon. 1978. Increased spontaneous polyclonal activation of B lymphocytes in mice with spontaneous autoimmune disease. J. Immunol. 121: 2213.