Comparison of effects of adrenocorticotropin and lys-γ3 melanocyte-stimulating hormone on steroidogenesis, adenosine 3′,5′-monophosphate production, and phospholipid metabolism in rat adrenal fasciculata-reticularis cells in vitro

Endocrinology

Volumn 112, Issue 1, 1983, Pages 129-132

  Farese, Robert V ^a,b   Ling, Nicholas C ^a,b   Sabir, Mohammad A ^a,b   Larson, Ronald E ^a,b   Trudeau, Walter L ^a,b  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

^b SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOTROPIN; CYCLIC AMP; INTERMEDIN; PHOSPHATIDYLINOSITOL; PHOSPHOLIPID;

ADRENAL GLAND; ANIMAL; ARTICLE; CATTLE; COMPARATIVE STUDY; DOSE RESPONSE; DRUG EFFECT; METABOLISM; RAT;

ADRENAL GLANDS; ANIMAL; CATTLE; COMPARATIVE STUDY; CORTICOTROPIN; CYCLIC AMP; DOSE-RESPONSE RELATIONSHIP, DRUG; MSH; PHOSPHATIDYLINOSITOLS; PHOSPHOLIPIDS; RATS; SUPPORT, U.S. GOV'T, NON-P.H.S.;

EID: 0020651322     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/endo-112-1-129     Document Type: Article

References (18)

1. Eipper BA, Mains RE 1980 Structure and biosynthesis of proad-renocorticotropin/endorphin and related peptides. Endocr Rev 1:1
2. Nakanishi S, Inoue A, Kita T, Nakamura M, Chang ACY, Cohen SN, Numa S 1979 Nucleotide sequence of cloned cDNA for bovine corticotropin-β-lipotropin precursor. Nature 278:423
3. Pedersen RC, Brownie AC 1980 Adrenocortical response to corticotropin is potentiated by part of the amino-terminal region of procorticotropin/endorphin. Proc Natl Acad Sci USA 77:2239
4. Pedersen RC, Brownie AC 1980 Pro-adrenocorticotropin/endor-phin-derived peptides: coordinate action on adrenal steroidogenesis. Science 208:1044
5. Al-Dujaili EAS, Hope J, Estivariz FE, Lowry PJ, Edwards CRW 1981 Circulating human pituitary pro-y-melanotropin enhances the adrenal response to ACTH. Nature 291:156
6. Pedersen RC, Brownie AC 1979 Failure of ACTH to mimic the stress-induced activation of rat adrenocortical cholesterol ester hydrolase in vivo. J Steroid Biochem 11:1393
7. Boyd GS, Trzeciak WH 1973 Cholesterol metabolism in the adrenal cortex: studies on the mode of action of ACTH. Ann NY Acad Sci 212:361
8. Beckett GJ, Boyd GS 1977 Purification and control of bovine adrenal cortical cholesterol ester hydrolase and evidence for activation of the enzyme by phosphorylation. Eur J Biochem 72:223
9. Naghshineh S, Treadwell CR, Gallo LI, Vahouny GV 1978 Proteinkinase mediated phosphorylation of a purified sterol ester hydrolase from bovine adrenal cortex. J Lipid Res 19:561
10. Farese RV, Sabir AM 1979 Polyphosphorylated glycerolipids mimic adrenocorticotropin-induced stimulation of mitochondrial pregnenolone synthesis. Biochim Biophys Acta 575:299
11. Farese RV, Sabir AM 1980 Polyphosphoinositides: stimulator of mitochondrial cholesterol sidechain cleavage and possible identification as an adrenocorticotropin-induced, cycloheximide-sensitive, cytosolic, steroidogenic factor. Endocrinology 106:1869
12. Farese RV, Sabir AM, Vandor SL, Larson RE 1980 Are polyphosphoinositides the cycloheximide-sensitive mediator in the steroidogenic actions of adrenocorticotropin and adenosine-3',5'-mono-phosphate? J Biol Chem 255:5728
13. Farese RV, Sabir MA, Larson RE 1980 On the mechanism whereby ACTH and cyclic-AMP increase adrenal polyphosphoinositides: rapid stimulation of the synthesis of phosphatidic acid and derivatives of CDP-diacylglycerol. J Biol Chem 255:7232
14. Fujita K, Aguilera G, Catt KJ 1979 The role of cyclic AMP in aldosterone production by isolated zona glomerulosa cells. J Biol Chem 254:8567
15. Ling N, Ying S, Minick S, Guillemin R 1979 Synthesis and biological activity of four y-melanotropin peptides derived from the cryptic region of the adrenocorticotropin/ /Mipotropin precursor. Life Sci 25:1733
16. Farese RV, Prudente WJ 1978 On the role of intra-adrenal unes-terified cholesterol in the steroidogenic effect of corticotropin. Biochim Biophys Acta 544:77
17. Crivello JF, Jefcoate CR 1980 Intracellular movement of cholesterol in rat adrenal cells. Kinetics and effects of inhibitors. J Biol Chem 255:8144
18. Pedersen RC, Ling N, Brownie AC 1982 Immunoreactive y-melan-otropin in rat pituitary and plasma: a partial characterization. Endocrinology 110:825