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Journal of Antibiotics

Volumn 36, Issue 5, 1983, Pages 604-607

Microbial hydroxylation of ML-236B (compactin) and monacolin K (MB-530B)

(6) Serizawa, Nobufusa a Nakagawa, Keiko a Hamano, Kiyoshi a Tsujita, Yoshio a Terahara, Akira a Kuwano, Harumitsu a

a DAIICHI SANKYO CO (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

3 HYDROXYMONACOLIN K CARBOXYLIC ACID METHYL ESTER; 3BETA HYDROXYCOMPACTIN; 6ALPHA HYDROXYISOMONACOLIN K CARBOXYLIC ACID METHYL ESTER; COMPACTIN; MEVINOLIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CHOLESTEROL SYNTHESIS; DRUG ANALYSIS; DRUG COMPARISON; DRUG IDENTIFICATION; DRUG ISOLATION; DRUG METABOLISM; DRUG SCREENING; HYDROXYLATION; IN VITRO STUDY; MICROORGANISM; MUCOR HIEMALIS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRELIMINARY COMMUNICATION; STRUCTURE ACTIVITY RELATION; THIN LAYER CHROMATOGRAPHY; ULTRAVIOLET SPECTROPHOTOMETRY;

EID: 0020612057 PISSN: 00218820 EISSN: 18811469 Source Type: Journal
DOI: 10.7164/antibiotics.36.604 Document Type: Letter

Times cited : (104)

References (6)

1
- 0017055252
- new inhibitors of cholesterogenesis produced by Penicillium citrinum.
- Ml-236a, ML-236B, and ML-236C
- Endo, A.; M. Kuroda & Y. Tsujita: Ml-236a, ML-236B, and ML-236C, new inhibitors of cholesterogenesis produced by Penicillium citrinum. J. Antibiotics 29: 1346~1348, 1976
- (1976) J. Antibiotics , vol.29 , pp. 1346-1348
- Endo, A.¹ Kuroda, M.² Tsujita, Y.³

2
- 0017043554
- Competitive inhibition of 3-hydroxy-3-methylglutaryl Coenzyme A reductase by ML-236A and ML-236B fungal metabolites, having hypocholesterolemic activity
- Endo, A.; M. Kuroda & K. Tanzawa: Competitive inhibition of 3-hydroxy-3-methylglutaryl Coenzyme A reductase by ML-236A and ML-236B fungal metabolites, having hypocholesterolemic activity. FEBS Lett. 72: 323~326, 1976
- (1976) FEBS Lett , vol.72 , pp. 323-326
- Endo, A.¹ Kuroda, M.² Tanzawa, K.³

3
- 0016913421
- Crystal and molecular structure of compactin, a new antifungal metabolite from Penicillium brevicompactum.
- Brown, A. G.; T. C. Smale, T. J. King, R. Hasenkamp & R. H. Thompson: Crystal and molecular structure of compactin, a new antifungal metabolite from Penicillium brevicompactum. J. Chem. Soc. Perkin I 1976: 1165— 1170, 1976
- (1976) J. Chem. Soc. Perkin I , pp. 1165-1170
- Brown, A.G.¹ Smale, T.C.² King, T.³ Thompson, R.⁴

4
- 85024433053
- Method of producing a novel physiologically active substance MB- 530B. Japan Kokai
- Tsujita, Y.; M. Kuroda, K. Tanzawa, S. Iwadoh & K. Furuya: Method of producing a novel physiologically active substance MB- 530B. Japan Kokai 55–150 898, Nov. 25, 1980; Belgi. Pat. 882325, Sep. 19, 1980
- (1980) Belgi. Pat. 882325 , pp. 55-150
- Tsujita, Y.¹ Kuroda, M.² Tanzawa, K.³ Iwadoh, S.⁴ Furuya, K.⁵

5
- 0018592266
- a new hypochles-terolemic agent produced by a Monascus species
- Endo, A.: Monacolin K., a new hypochles-terolemic agent produced by a Monascus species. J. Antibiotics 32: 852—854, 1979
- (1979) J. Antibiotics , vol.32 , pp. 852-854
- Endo, A.¹

6
- 0018939225
- Springer: Mevinolin: A high potent competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase and a cholesterol-lowering agent
- Alberts, A. W.; J. Chen, G. Kuron, V. Hunt, J. Huff, C. Hoffman, J. Rothrock, M. Lopez, H. Joshua, E. Harris, A. Patchett, R. Monaghan, S. Currie, E. Stapley, G. Albersschonberg, O.HEnsens, J.HlRSHFIELD, K. Hoogsteen, J. Liesch & J. Springer: Mevinolin: A high potent competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase and a cholesterol-lowering agent. Proc. Natl. Acad. Sci. USA. 77: 3957–3961, 1980
- (1980) Proc. Natl. Acad. Sci. USA. , vol.77 , pp. 3957-3961
- Chen, J.¹ Kuron, G.² Hunt, V.³ Huff, J.⁴ Hoffman, C.⁵ Rothrock, J.⁶ Lopez, M.⁷ Joshua, H.⁸ Harris, E.⁹ Patchett, A.¹⁰ Monaghan, R.¹¹ Currie, S.¹² Stapley, E.¹³

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.