SCH 23390-The first selective dopamine D-1 antagonist

European Journal of Pharmacology

Volumn 91, Issue 1, 1983, Pages 153-154

  Hyttel, John ^a  

^a H LUNDBECK A S   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; BENZAZEPINE DERIVATIVE; CHLORPROTHIXENE; CLOPENTHIXOL; DOPAMINE RECEPTOR BLOCKING AGENT; FLUPENTIXOL; FLUPHENAZINE; PERPHENAZINE; PIMOZIDE; PRAZOSIN; RADIOISOTOPE; RECEPTOR; SULPIRIDE;

ANIMAL CELL; BRAIN; CENTRAL NERVOUS SYSTEM; CORPUS STRIATUM; DOPAMINERGIC SYSTEM; DRUG ANTAGONISM; DRUG RECEPTOR BINDING; FLUPENTIXOL H 3; HALOPERIDOL H 3; NONHUMAN; PHARMACOKINETICS; PIFLUTIXOL H 3; RAT; SPIPERONE H 3;

ANIMAL; BENZAZEPINES; BRAIN; IN VITRO; MALE; MEMBRANES; PRAZOSIN; RATS; RATS, INBRED STRAINS; RECEPTORS, DOPAMINE; RECEPTORS, DOPAMINE D1; SCH-23390;

EID: 0020595626     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-2999(83)90381-3     Document Type: Article

References (5)

1. Decreased antistereotypic effect of neurleptics after additional treatment with a benzodiazepine, a GABA-agonist and an anticholinergic compound
2. Neuroleptics and the clinical implications of adaptation of dopamine neurons
3. 3H-cis(Z)-flupenthixol binding and on adenylate cyclase activity in vitro
4. Preferential labelling of adenylate cyclase coupled dopamine receptors with thioxanthene neuroleptics
5. SCH 23390, A benzazepine with atypical effects on dopaminergic systems