Enteral administration of agar as an effective adjunct to phototherapy of neonatal hyperbilirubinemia

Pediatric Research

Volumn 17, Issue 10, 1983, Pages 810-814

  Odell, Gerard B ^a   Gutcher, Gary R ^a   Whitington, Peter F ^a   Yang, Gloria ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGAR; BILIRUBIN; PLACEBO;

BLOOD AND HEMOPOIETIC SYSTEM; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED STUDY; DRUG THERAPY; HUMAN; HYPERBILIRUBINEMIA; INFANT; LIVER; NEWBORN; ORAL DRUG ADMINISTRATION; PHOTOTHERAPY; THERAPY;

AGAR; BILIRUBIN; ENTERAL NUTRITION; FEMALE; HUMAN; INFANT, NEWBORN; JAUNDICE, NEONATAL; MALE; PHOTOTHERAPY; PROSPECTIVE STUDIES; SUPPORT, U.S. GOV'T, P.H.S.; TIME FACTORS;

EID: 0020551273     PISSN: 00313998     EISSN: 15300447     Source Type: Journal    
DOI: 10.1203/00006450-198310000-00009     Document Type: Article

References (33)

1. Final report on the Committee on Phototherapy in the Newborn. Division of Medical Sciences, Assembly of Life Sciences, National Research Council. (National Academy of Sciences, Washington D.C., 1974)
2. Brown, A. K. and Mc Donagh, A. F.: Phototherapy for neonatal hyperbilirubinemia: efficacy, mechanism and toxicity. Avd. Pediat., 27: 341 (1980).
3. Cremer, R. J., Perryman, P. W., and Richards, D. K.: Influence of light on the hyperbilirubinemia of infants. Lancet, i:1094 (1958).
4. Ostrow, J. D.: Photocatabolism of labeled bilirubin in the congenitally jaundiced Gunn rat. J. Clin. Invest., 50: 707 (1971).
5. Lund, H. T. and Jacobsen, J.: Influence of phototherapy on the biliary bilirubin excretion pattern in newborn infants with hyperilirubinemia. J. Pediatr. 85: 262 (1974).
6. Ostrow, J. D., Berry, C. S., and Zarembo, J. E.: Studies on the mechanism of phototherapy in the congenitally jaundiced rat. In: Odell G. B., Schaffer, R., Simoupoulis, A., (Eds.). Phototherapy in the Newborn: an overview, pp. 74-92 (National Academy of Sciences, Washington D.C., 1974)
7. Mc Donagh, A. F., and Ramonas, L. M.: Jaundice phototherapy: microflow-cell photometry reveals rapid biliary response of Gunn rats to light. Science 201: 829 (1978).
8. Stoll, M. S., Zenone, E. A., Ostrow, J. D., and Zarembo, J. E.: Preparation and properties of bilirubin photoisomers. Biochem. J., 183: 139 (1979).
9. Onishi, S., Kawade, N., Itoh, S., Isobe, K., and Sugiyama, S.: High-pressure liquid chromatographic analysis of anaerobic photo-products of bilirubin-IXa in vitro and its comparison with photo-products in vivo. Biochem. J., 190: 527 (1980).
10. Erlinger, S. D., Dhumeaux, J. F., and Benhamou, J. P.: Hepatic handling of unconjugated dyes in the Dubin-Johnson syndrome. Gastroenterology, 64:106 (1973).
11. Lester, R. and Schmid, R.: Intestinal absorption of bile pigments. I. The enterohepatic circulation of bilirubin in the rat. J. Clin. Invest., 42: 736 (1963).
12. Poland, R. L. and Odell, G. B.: Physiologicjaundice: the enterohepatic circulation of bilirubin. N. Engl. J. Med. 284: 1 (1971).
13. Windorfer, A. Jr., Kunzer, W., Bolze, H., Ascher, K., Wilcken, F., and Hoehne, K.: Studies on the effect of orally administered agar on the serum bilirubin level of premature infants and mature newborns. Acta Paediatr. Scand., 64: 699 (1975).
14. Maurer, H. M., Shumway, C. N., Draper, D. A., and Hossaini, A. A.: Controlled trial comparing agar, intermittent phototherapy and continuous phototherapy for reducing neonatal hyperbilirubinemia. J. Pediatr., 82: 73 (1973).
15. Schellong, G., Quakermack, K., and Fuhrmans, B.: The influence of agar feeding on serum bilirubin in physiologicjaundice of the newborn infant. Z. Geburt- shilfe Perinatol., 178: 34 (1974).
16. Romagnoli, C., Polidori, M., Foschini, L., Cataldi, P., de Turics, P., Tortorolo, G., and Mastrangelo R.: Agar in the management of hyperbilirubinemia in the premature baby. Arch. Dis. Child. 50: 202 (1975).
17. Meloni, T., Costa, S., Corti, R., and Cutillo, S.: Agar in control of hyperbilirubinemia of full-term newborn infants with erythrocyte G-6-PD deficiency. Biol. Neonate, 34: 295 (1978).
18. Ebbesen, F., Miller, J. Agar ingestion combined with phototherapy in jaundiced newborn infants. Biol. Neonate 31: 7-9 (1977).
19. Poland, R. L., and Odell, G. B.: The binding of bilirubin to agar. Proc. Soc. Exp. Biol. Med., 146: 1114 (1974).
20. Odell, G. B., Bolen, J. L., Poland, R. L., Seungdamrong S., and Cukier J. O.: Protection from bilirubin nephropathy in jaundiced Gunn rats. Gastroenter ology, 66: 1218 (1974).
21. Odell, G. B.: Neonatal hyperbilirubinemia, pp. 44-47 (Grune and Stratton, New York, 1980).
22. Cukier, J. L., Maglalang, A. C., and Odell, G. B.: Increased osmotic fragility of erythrocytes in chronically jaundiced rats after phototherapy. Acta Paediatr. Scand. 68: 903 (1979).
23. Malloy, H. T., Evelyn, K. A.: The determination of bilirubin with the photoelectric colorimeter. J. Biol. Chem. 119: 481 (1937).
24. Schwarz, M. P., von Bergman, K., and Paumgartner, G.: A simple method for the estimation of bile acids in serum. Clin. Chim. Acta, 50: 197 (1974).
25. Boyer, J., Baron, D. N., and Talalay, P.: Purification and properties of a 3a- hydroxysteroid dehydrogenase from Pseudomonas testosteroni. Biochemistry, 4: 1825 (1965).
26. Brownlee, K. A.: Industrial experimentation. 4th edition (Chemical Publishing Co., New York, 1953).
27. Dixon, W. J., Massey, F. J., Jr.: Introduction to statistical analysis. 3rd edition (McGraw-Hill Co., New York, 1969).
28. Arrowsmith, W. A., Payne, R. B., and Littlewood, J. M.: Comparison of treatments for congenital non-obstructive non-haemolytic hyperbilirubinemia. Arch. Dis. Child. 50: 197 (1975).
29. McDonagh, A. F., Palma, L. A., and Lightner, D. A.: Blue light and bilirubin excretion. Science, 208: 145 (1980).
30. John, E.: Complications of phototherapy in neonatal hyperbilirubinemia. Aust. Paediatr. J., 11: 53 (1975).
31. Rubaltelli, F. F., and Largajolli, G.: Effect of light exposure on gut transit time in jaundiced newborns. Acta Paediatr. Scand., 62: 146 (1973).
32. Whitington, P. F., Olsen, W. A., and Odell, G. B.: The effect of bilirubin on the function of hamster small intestine. Pediatr. Res., 15: 1009 (1981).
33. Li, B., Whitington, P. F., and Odell, G. B.: Reversal of bilirubin-induced small bowel secretion by agar. Pediatr. Res., 13:403A (1979).