In vivo effects of α-dl-Difluoromethylornithine on the metabolism and morphology of Trypanosoma brucei brucei

Molecular and Biochemical Parasitology

Volumn 7, Issue 3, 1983, Pages 209-225

  Bacchi, Cyrus J ^a   Garofalo, Joanne ^a   Mockenhaupt, Dianne ^a   McCann, Peter P ^b   Diekema, Keith A ^b   Pegg, Anthony E ^c   Nathan, Henry C ^a   Mullaney, Elizabeth A ^a   Chunosoff, Laura ^a   Sjoerdsma, Albert ^b   Hutner, Seymour H ^a  

^a PACE UNIVERSITY   (United States)

^b Merrell Dow Research Institute   (United States)

^c PENN STATE MILTON S HERSHEY MEDICAL CENTER   (United States)

Author keywords

Morphological changes; Polyamine metabolism; S Adenosylmethionine; Synthesis of macromolecules; Trypanosoma brucei brucei; dl Difluoromethylornithine

Indexed keywords

EFLORNITHINE; METHIONINE; ORNITHINE H 3; PUTRESCINE H 3; SPERMIDINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CHEMOTHERAPY; DRUG INHIBITION; DRUG METABOLISM; METABOLISM; NONHUMAN; PROTOZOON; THERAPY; TRYPANOSOMA BRUCEI;

ANIMALS; DNA; EFLORNITHINE; FEMALE; KINETICS; MACROMOLECULAR SUBSTANCES; ORNITHINE; POLYAMINES; PROTEIN BIOSYNTHESIS; RATS; RATS, INBRED STRAINS; RNA; TRYPANOSOMA BRUCEI BRUCEI; TRYPANOSOMIASIS, AFRICAN;

ANIMALIA; EUKARYOTA; PROTOZOA; TRYPANOSOMA; TRYPANOSOMA BRUCEI BRUCEI;

EID: 0020505557     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/0166-6851(83)90022-1     Document Type: Article

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