Diazepam in high doses is effective in schizophrenia

Progress in Neuropsychopharmacology and Biological Psychiatry

Volumn 6, Issue 4-6, 1982, Pages 513-516

  Nestoros, Joannis N ^a   Suranyl Cadotte, Barbara E ^a   Spees, Richard C ^a   Schwartz, George ^a   Vasavan Nair, N P ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

clinical study; diazepam; schizophrenia

Indexed keywords

4 AMINOBUTYRIC ACID; DIAZEPAM; PLACEBO;

CENTRAL NERVOUS SYSTEM; CLINICAL ARTICLE; DRUG THERAPY; HUMAN; SCHIZOPHRENIA; THERAPY;

ADULT; DIAZEPAM; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; FEMALE; HUMANS; MALE; PSYCHIATRIC STATUS RATING SCALES; SCHIZOPHRENIA, PARANOID; SOCIAL ADJUSTMENT;

EID: 0020464440     PISSN: 02785846     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0278-5846(82)80141-3     Document Type: Article

References (15)

1. Preface
2. Molecular mechanisms in the receptor action of benzodiazepines
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4. ECDEU assessment manual for psychopharmacology
5. A Nurses' Observation Scale for Inpatient Evaluation (NOSIE): A new scale for measuring improvement in chronic schizophrenia
6. Schizophrenia: overview of treatment methods
7. The dopamine hypothesis of schizophrenia: a review
8. High doses of diazepam improve neuroleptic-resistant schizophrenic patients
9. Benzodiazepines in schizophrenia: a need for reassessment
10. The Brief Psychiatric Rating Scale
11. An hypothesis suggesting that there is a defect in the GABA system in schizophrenia
12. Disinhibition as an organizing principle in the nervous system - the role of the GABA system. Application to neurologic and psychiatric disorders
13. γ-Aminobutyric acid (GABA) and the dopamine hypothesis of schizophrenia
14. Decreased in vivo dopamine release in the striatum with diazepam