Pyridone-carboxylic Acids as Antibacterial Agents. I. Synthesis and Antibacterial Activity of 1-Alkyl-1,4-dihydro-4-oxo-1,8- and 1,6-naphthyridine-3-carboxylic Acids

Chemical and Pharmaceutical Bulletin

Volumn 30, Issue 7, 1982, Pages 2399-2409

  Hirose, Tohru ^a   Mishio, Shinsaku ^a   Matsumoto, Jun ichi ^a   Minami, Shinsaku ^a,b  

^a DAINIPPON SUMITOMO PHARMA CO LTD   (Japan)

^b Teikoku Chemical Industry   (Japan)

Author keywords

1,6 naphthyridine; 1,8 naphthyridine; antibacterial activity; NOE experiment; structure activity relationship; synthesis

Indexed keywords

NALIDIXIC ACID; PIPEMIDIC ACID; PIROMIDIC ACID;

1,4 DIHYDRO 4 OXO 1,6 NAPHTHYRIDINE 3 CARBOXYLIC ACID DERIVATIVE; 1,4 DIHYDRO 4 OXO 1,8 NAPHTHYRIDINE 3 CARBOXYLIC ACID DERIVATIVE; DRUG ANALYSIS; DRUG COMPARISON; DRUG IDENTIFICATION; DRUG SCREENING; DRUG SYNTHESIS; IN VITRO STUDY; INFRARED SPECTROMETRY; NONHUMAN; PRELIMINARY COMMUNICATION; PSEUDOMONAS AERUGINOSA; STRUCTURE ACTIVITY RELATION; ULTRAVIOLET SPECTROPHOTOMETRY;

ANTI-INFECTIVE AGENTS; BACTERIA; CARBOXYLIC ACIDS; NAPHTHYRIDINES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0020457050     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.30.2399     Document Type: Article

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