Structure of human immunoglobulin gamma genes: implications for evolution of a gene family

Cell

Volumn 29, Issue 2, 1982, Pages 671-679

  Takahashi, Naoki ^a   Ueda, Shintaro ^a   Obata, Masahiro ^a   Nikaido, Toshio ^a   Nakai, Sumiko ^a   Honjo, Tasuku ^a  

^a OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN G FRAGMENT; UNCLASSIFIED DRUG;

ARTICLE; BLOOD AND HEMOPOIETIC SYSTEM; EVOLUTION; GENE STRUCTURE; HEREDITY; HUMAN CELL; IMMUNOGLOBULIN GENE; NORMAL HUMAN; NUCLEOTIDE SEQUENCE;

ANIMALS; BASE SEQUENCE; CLONING, MOLECULAR; CROSSING OVER, GENETIC; DNA; DNA, RECOMBINANT; EVOLUTION; GENE AMPLIFICATION; GENES, MHC CLASS II; HUMANS; IMMUNOGLOBULIN GAMMA-CHAINS; IMMUNOGLOBULIN HEAVY CHAINS; LINKAGE (GENETICS); MICE; RECOMBINATION, GENETIC;

EID: 0020317803     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/0092-8674(82)90183-0     Document Type: Article

References (48)

1. Screening λgt recombinant clones by hybridization to single plaques in situ
2. Charon phages: safer derivatives of bacteriophage lambda for DNA cloning
3. Organization and expression of eucaryotic split genes coding for proteins
4. Repeated sequences in DNA: hundreds of thousands of copies of DNA sequences have been incorporated into the sequences of higher organisms
5. μ heavy chain immunoglobulin gene segment contains three intervening sequences separating domains
6. Implications of RNA-RNA splicing in evolution of eukaryotic cells
7. An immunoglobulin heavy-chain gene is formed by at least two recombinational events
8. Electron microscope heteroduplex methods for mapping regions of base sequence homology in nucleic acids
9. Genes in pieces: were they ever together?
10. Immunoglobulin heavy chain gene organization of a myeloma genomic clone containing variable and α constant regions
11. The covalent structure of an entire γG immunoglobulin molecule
12. Why genes in pieces?
13. Cloning and complete nucleotide sequence of mouse immunoglobulin γ1 chain gene
14. Rearrangement of immunoglobulin genes during differentiation and evolution
15. Cloning immunoglobulin γ2b chain gene of mouse: characterization and partial sequence determination
16. Rearrangement of immunoglobulin γ1-chain gene and mechanism for heavy-chain class switch
17. Repetitive sequence in class-switch recombination regions of immunoglobulin heavy chain genes
18. Complete nucleotide sequence of mouse immunoglobulin μ gene and comparison with other immunoglobulin heavy chain genes
19. The isolation and characterization of linked δ- and β-globin genes from a cloned library of human DNA
20. Recombination, mutation, or constitutive expression at a Gm locus and familial hypergammaglobulinemia
21. Mapping of heavy chain genes for mouse immunoglobulins M and D
22. Exon shuffling generates an immunoglobulin heavy chain gene
23. A new method for sequencing DNA
24. Primary structure of the “hinge” region of human IgG3: probable quadruplication of a 15-amino acid residue basic unit
25. Nucleotide sequence divergence and functional constraint in mRNA evolution
26. Nucleotide sequence divergence of mouse immunoglobulin γ1 and γ2b chain genes and the hypothesis of intervening sequence-mediated domain transfer
27. Genetic markers of the heavy chain subgroups of human γG globulin
28. μ gene is composed of simple tandem repetitive sequences
29. Cloning of mouse immunoglobulin ϵ gene and its location within the heavy chain gene cluster
30. Immunoglobulin γ1 heavy chain gene: structural gene sequences in a bacterial plasmid
31. Human immunoglobulin subclass. Partial amino acid sequence of the constant region of a γ4 chain
32. γ genes and associated switch sequences
33. Recombination activities of E. coli RecA protein
34. Evolutionary approach to the question of immunoglobulin heavy chain switching: evidence from cloned human and mouse genes
35. Linkage of the four γ subclass heavy chain genes
36. Domains and the hinge region of an immunoglobulin heavy chain are encoded in separate DNA segments
37. Generation length and rates of hominoid molecular evolution
38. Ordering of mouse immunoglobulin heavy chain genes by molecular cloning
39. Organization of the constant-region gene family of the mouse immunoglobulin heavy chain
40. Detection of specific sequences among DNA fragments separated by gel electrophoresis
41. Nucleotide sequences of class switch recombination region of the mouse immunoglobulin γ2b-chain gene
42. Cloning of human immunoglobulin μ gene and comparison with mouse μ gene
43. Organization of immunoglobulin heavy chain genes and genetic mechanism of class switch
44. Sequence of the cloned gene for the constant region of murine γ2b immunoglobulin heavy chain
45. The primary structure of a human IgG2 heavy chain: genetic, evolutionary and functional implications
46. Complete nucleotide sequence of immunoglobulin γ2b chain gene cloned from newborn mouse DNA
47. The complete nucleotide sequence of mouse immunoglobulin γ2a and evolution of heavy chain genes: further evidence for intervening sequence-mediated domain transfer
48. Nucleotide sequences of gene segments encoding membrane domains of immunoglobulin γ chains