Biosynthesis of the MHC-linked complement proteins (C2, C4 and factor B) by mononuclear phagocytes

Molecular Immunology

Volumn 19, Issue 10, 1982, Pages 1279-1285

  Colten, Harvey R ^a,b  

^a Children's Hospital Medical Center   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALTERNATIVE COMPLEMENT PATHWAY C3 C5 CONVERTASE; COMPLEMENT COMPONENT C2; COMPLEMENT COMPONENT C4;

GENE EXPRESSION; HEREDITY; IN VITRO STUDY; MAJOR HISTOCOMPATIBILITY COMPLEX; MONONUCLEAR CELL; PHAGOCYTE; RETICULOENDOTHELIAL SYSTEM; SHORT SURVEY;

ANIMAL; COMPLEMENT 2; COMPLEMENT 4; COMPLEMENT FACTOR B; DNA, CIRCULAR; ENZYME PRECURSORS; GUINEA PIGS; HUMAN; LIVER; MACROPHAGES; MAJOR HISTOCOMPATIBILITY COMPLEX; MICE; MOLECULAR WEIGHT; MONOCYTES; NUCLEIC ACID HYBRIDIZATION; PHAGOCYTES; POLYMORPHISM (GENETICS); RATS; SARCOIDOSIS;

EID: 0020317197     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/0161-5890(82)90294-2     Document Type: Article

References (59)

1. Complement and the MHC
2. Genetic polymorphism in human glycine-rich beta-glycoprotein
3. Serum proteins and other genetic markers of the blood
4. Isolation by fluorescence activated cell sorting (FACS) of macrophages bearing C4 on their surface membrane
5. Inherited polymorphism of human C4 as revealed by desialyzation
6. Linkage of total deficiency of the second component (C2) of the complement system and of genetic C2 polymorphism to the major histocompatibility complex of the guinea pig
7. Inherited polymorphism of guinea pig factor B and C4 evidence for genetic linkage between the C4 and Bf loci
8. Partial sequence of human complement component factor B: novel type of serine esterase
9. Control of complement synthesis and secretion in bronchoalveolar and peritoneal macrophages
10. Complement biosynthesis in human breast milk macrophages and blood monocytes
11. In vitro synthesis of a regulator of mammalian gene expression
12. Biosynthesis of serum complement
13. Biosynthesis of the second and fourth components of complement in vitro by tissue isolated from guinea pigs with genetically determined C4 deficiency
14. Synthesis and secretion of complement proteins by macrophages
15. Biosynthesis of the fourth component of complement (C4) by C4-deficient guinea pig-HeLa cell hybrids
16. Enzymatic activity of the second component of complement
17. Ueber Haemolysine Berl
18. A biosynthetic defect in monocytes from human with genetic deficiency of the second component of complement (C2)
19. Synthesis of the second component of complement by long-term primary cultures of human monocytes
20. Structural and functional differences between the H-2 controlled Ss and Slp proteins
21. Purification and characterization of mouse serum protein with specific binding affinity for C4 (Ss protein)
22. The biosynthesis of complement components
23. Evidence for linkage between HL-A histocompatibility genes and those involved in the synthesis of the second component of complement
24. A single chain precursor of human C4 in serum
25. Inherited deficiency of the second component of complement: rheumatic disease association
26. Primary structure of pro-C4, the precursor of the fourth component of guinea pig complement
27. Precursor complement protein (pro-C4) is converted in vitro to native C4 by plasmin
28. Molecular basis of C2 (C2D) and C4 (C4D) deficiencies in guinea pigs.
29. C4a: the third anaphylatoxin of the human complement system
30. Single-chain C4 from human plasma
31. The alternative pathway of complement activation
32. Cell-free synthesis of the fourth component of guinea pig complement (C4): identification of a precursor of serum C4 (pro-C4)
33. Genetic defect in biosynthesis of the precursor form of the fourth component of complement
34. Allotypes of complement components in man
35. Pulmonary sarcoidosis: a disorder of helper T-lymphocyte activity at sites of disease activity
36. Production of the second component of complement by human monocytes: stimulation by antigen activated lymphocytes or lymphokines
37. The major histocompatibility complex (MHC) linked complement proteins C2 C4 and factor B effect of glycosylation on their secretion and catabolism
38. 2 and BW15
39. Biosynthesis of membrane and secreted factor B by mouse peritoneal macrophages
40. Two HLA-linked loci controlling the fourth component of human complement
41. H-2 linked murine factor B phenotypes
42. Partial amino acid sequences of the murine fourth component of complement (C4): demonstration of homology with human C4 and identification of the amino-terminal subunit in pro-C4
43. Structural characterization of the murine fourth component of complement and sex-limited proteins and their precursors: evidence for two loci in the S-region of the H-2 complex
44. A sex-linked serum protein, variant in the mouse: inheritance and association with the H-2 region
45. Mapping of the structural gene of the second component of complement with respect to the human major histocompatibility complex
46. The proteolytic activation system of complement
47. Parallel studies of complement and coagulation. IV. Effect of carbon tetrachloride
48. Molecular characterization of the Ss and Slp (C4) proteins of the mouse H-2 complex: subunit composition chain size polymorphism and an intracellular (Pro-Ss) precursor
49. Murine complement factor B (Bf): sexual dimorphism and H-2 linked polymorphism
50. Characterization of the oligosaccharide units of the fourth component of complement (Ss protein) synthesized by murine macrophages
51. Structural polymorphism of the fourth component of human complement
52. Fourth component of human complement: description of a three polypeptide chain structure
53. A serologically detected variant in mouse serum inheritance and association with the histocompatibility H-2 locus
54. 2-macroglobulin
55. Biosynthesis of the complement components and the regulatory proteins of the alternative complement pathway by human peripheral blood monocytes
56. Assignment of the gene for the third component of human complement (C3) to chromosome 19 using human mouse somatic cell hybrids
57. Isolation of a c-DNA clone corresponding to the M H C linked complement protein—factor B
58. Plasma membrane polypeptide of resident and activated mouse peritoneal macrophages