ROLE OF CENTRAL β‐ADRENOCEPTORS IN THE CONTROL OF PENTYLENETETRAZOL‐INDUCED CONVULSIONS IN RATS

British Journal of Pharmacology

Volumn 75, Issue 3, 1982, Pages 441-446

  LOUIS, W J ^a   PAPANICOLAOU, JENNY ^a   SUMMERS, R J ^a   VAJDA, F J E ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; PENTETRAZOLE; PINDOLOL; PRACTOLOL; PROPRANOLOL; TIMOLOL;

ANIMAL EXPERIMENT; AUTONOMIC NERVOUS SYSTEM; BLOOD BRAIN BARRIER; CENTRAL NERVOUS SYSTEM; CONVULSION; INTRAPERITONEAL DRUG ADMINISTRATION; ORAL DRUG ADMINISTRATION; RAT;

ADRENERGIC BETA-ANTAGONISTS; ANIMAL; ANTICONVULSANTS; CONVULSIONS; FEMALE; INJECTIONS, INTRAVENTRICULAR; MALE; PENTYLENETETRAZOLE; PINDOLOL; RATS; RATS, INBRED STRAINS; RECEPTORS, ADRENERGIC; RECEPTORS, ADRENERGIC, BETA; SUPPORT, NON-U.S. GOV'T;

EID: 0020082361     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.1982.tb09159.x     Document Type: Article

References (31)

1. The anticonvulsant action of the (−)‐and (+)‐enantiomers of propranolol
2. 2‐adrenoceptor antagonist
3. A facultative action of reserpine on the central nervous system
4. Cyclic AMP in cerebrospinal fluid of rats: Effects of electroconvulsive shock
5. Selective blockade of adrenoceptive beta receptors in the heart
6. Brain distribution of propranolol in the rat
7. Cyclic nucleotides in epileptic brain: Effects of pentylenetetrazol on regional cyclic AMP and cyclic GMP levels in vivo
8. A proposed common mechanism of action for general and local anaesthetics in the central nervous system
9. Clinical pharmacology of the new beta adrenergic blocking drugs. Part 1. Pharmacodynamic and pharmacokinetic properties
10. Comparative antihypertensive effects and tissue distribution of beta adrenergic blocking drugs
11. Effects of reserpine, propranolol, and aminophylline on seizure activity and CNS cyclic nucleotides
12. The anticonvulsant effects of propranolol and β‐adrenergic blockade
13. The relative significance of norepinephrine, dopamine and 5‐hydroxytryptamine in electroshock seizure in the rat
14. Central monoamines and convulsive thresholds in mice and rats
15. Some effects of propranolol on the central nervous system
16. Disposition of propranolol isomers in mice
17. Anticonvulsant activity of some β‐adrenoceptor blocking agents in mice
18. Catecholamines and convulsions
19. Direct evidence for an interaction of β‐adrenergic blockers with the 5‐HT receptor
20. Central nervous system effects of four β‐adrenergic receptor blocking agents
21. Cyclic AMP concentration and enzyme activities of cerebrospinal fluid in patients with epilepsy or central nervous system damage
22. 3H‐norepinephrine into the lateral ventricle of the rat brain
23. 2‐selective adrenoceptor antagonist and can be used to characterise beta‐adrenoceptor populations in tissues
24. Role of β‐adrenoeeptors in the anticonvulsant effect of propranolol on pentylenetetrazol‐induced convulsions in rats
25. Increase in the content of adenosine 3′,5′‐monophosphate in mouse forebrain during seizures, and prevention of the increase by methylxanthines
26. β‐Adrenoceptor blocking drugs in hypertension
27. Tissue levels of several radiolabeled β‐adrenoceptor antagonists after intravenous administration in rats
28. Anticonvulsant properties of procaine, cocaine, adiphenine and related structures
29. Uptake of the beta‐adrenergic blocking agents propranolol and timolol by rodent brain: Relationship to central pharmacological action
30. Production of epileptiform discharges by application of agents which increase cyclic AMP levels in rat cortex
31. Effects of some adrenergic agents on low frequency electroshock seizures