ISOLATION AND CHARACTERISATION OF RESISTANT HERPES SIMPLEX VIRUS AFTER ACYCLOVIR THERAPY

The Lancet

Volumn 319, Issue 8269, 1982, Pages 421-423

  Burns, WilliamH ^a   Santos, GeorgeW ^a   Saral, Rein ^a   Laskin, OscarL ^a   Lietman, PaulS ^a   Mclaren, Colin ^b   Barry, DavidW ^b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b GLAXOSMITHKLINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACICLOVIR; ANTIVIRUS AGENT; THYMIDINE KINASE;

ANIMAL EXPERIMENT; BLOOD AND HEMOPOIETIC SYSTEM; BONE MARROW TRANSPLANTATION; DRUG RESISTANCE; HERPES SIMPLEX VIRUS; HERPES VIRUS; IN VITRO STUDY; MUTANT; VIRUS ISOLATION;

ACYCLOVIR; ADOLESCENT; BONE MARROW TRANSPLANTATION; CLINICAL TRIALS; DOUBLE-BLIND METHOD; GUANINE; HERPES SIMPLEX; HUMANS; MALE; MIDDLE AGED; MUTATION; RANDOM ALLOCATION; SIMPLEXVIRUS; THYMIDINE KINASE;

EID: 0020073621     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(82)91620-8     Document Type: Article

References (15)

1. Parenteral acyclovir therapy for herpesvirus infections in man
2. Acyclovir prophylaxis of herpes-simplex-virus infections, a randomized, double-blind, controlled trial in bone-marrow-transplant recipients
3. Controlled clinical trial of intravenous acyclovir in heart transplant patients with mucocutaneous herpes simplex infections
4. Acyclovir therapy for mucocutaneous herpes simplex infections in immunocompromised patients
5. Dye uptake methods for assessing viral cytopathogenicity and their application to interferon assays
6. Thymidine kinase from herpes simplex virus phosphorylates the new antiviral compound, 9-(2-hydroxyethoxymethyl) guanine
7. Bone marrow transplantation
8. Two distinct loci confer resistance to acycloguanosine in herpes simplex virus type 1
9. Isolation and characterization of acyclovir-resistant mutants of herpes simplex virus
10. Resistance of herpes simplex virus to acycloguanosine role of viral thymidine kinase and DNA polymerase loci
11. Pathogenicity in mice of strains of herpes simplex virus which are resistant to acyclovir in vitro and in vivo
12. Infectious disease during immune recovery after bone marrow transplantation