Altered glomerular permeability as a result of focal detachment of the visceral epithelium

Kidney International

Volumn 21, Issue 4, 1982, Pages 565-574

  Kanwar, Y S ^a   Rosenzweig, L J ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FERRITIN; SIALIDASE;

GLOMERULUS BASEMENT MEMBRANE; GLOMERULUS EPITHELIUM; GLOMERULUS FILTRATION; HUMAN CELL; KIDNEY; NEPHROTIC SYNDROME; RAT;

EID: 0020072270     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1038/ki.1982.63     Document Type: Article

References (41)

1. M.A. Venkatachalam M.J. Karnovsky R.S. Cotran Glomerular permeability: Ultrastructural studies in experimental nephrosis using horseradish peroxidase as a tracer J Exp Med 130 1969 381 399
2. M.A. Venkatachalam R.S. Cotran M.J. Karnovsky An ultrastructural study of glomerular permeability in aminonucleoside nephrosis using catalase as a tracer protein J Exp Med 132 1970 1168 1180
3. G.B. Ryan M.J. Karnovsky An ultrastructural study of the mechanisms of proteinuria in aminonucleoside nephrosis Kidney Int 8 1975 219 232
4. A.F. Michael E. Blau R.L. Vernier Glomerular polyanion. Alteration in aminonucleoside nephrosis Lab Invest 23 1970 649 657
5. Y.S. Kanwar M.G. Farquhar Anionic sites in the glomerular basement membrane. In vivo and in vitro localization to the laminae rarae by cationic probes J Cell Biol 81 1979 137 153
6. Y.S. Kanwar L.J. Rosenzweig D.I. Kerjaschki Glycosaminoglycan of the glomerular basement membrane in normal and nephrotic states Renal Physiol 4 1981 121 130
7. J.P. Caulfield M.G. Farquhar Loss of anionic sites from the glomerular basement membrane in aminonucleoside nephrosis Lab Invest 39 1978 505 512
8. Y.S. Kanwar M.G. Farquhar Detachment of endothelium and epithelium from the glomerular basement membrane produced by kidney perfusion with neuraminidase Lab Invest 42 1980 375 384
9. J.F. Rinehart S.K. Abul-Haj An improved method for histologic demonstration of acid mucopolysaccharides in tissues Arch Pathol Lab Med 52 1951 189 194
10. Y.S. Kanwar A. Linker M.G. Farquhar Increased permeability of the glomerular basement membrane to ferritin after removal of glycosaminoglycans (heparan sulfate) by enzyme digestion J Cell Biol 86 1980 688 693
11. R.L. Vernier B.W. Papermaster R.A. Good Aminonucleoside nephrosis. I. Electron microscopic study of the renal lesion in rats J Exp Med 109 1959 115 126
12. J.P. Caulfield J.J. Reid M.G. Farquhar Alterations of the glomerular epithelium in acute aminonucleoside nephrosis. Evidence for formation of occluding junctions and epithelial cell detachment Lab Invest 34 1976 43 59
13. E. Grishman J. Churg Focal glomerular sclerosis in nephrotic patients: an electron microscopic study of glomerular podocytes Kidney Int 7 1975 111 122
14. D.J. Davies D.B. Brewer J. Hardwicke Urinary proteins and glomerular morphometry in protein overload proteinuria Lab Invest 38 1978 232 243
15. E.E. Schneeberger A. O'Brien W.E. Grupe Altered glomerular permeability in Munich-Wistar rats with autologous immune complex nephritis Lab Invest 40 1979 227 235
16. H.V. Baeyer J.B. Van Liew J. Klassen J.W. Boylan Filtration of protein in the anti-glomerular basement membrane nephritic rat: A micropuncture study Kidney Int 10 1976 425 437
17. J. Sadowski P.R. Potvliege W. Gepts M. Staroukine P.P. Lambert Urea-induced proteinuria: a new experimental model Kidney Int 13 1978 253 256
18. R.L. Vernier J.S. Resnick S.M. Maver Recurrent hematuria and focal glomerulonephritis Kidney Int 7 1975 224 231
19. J.L. Olsen H.G. Rennke M.A. Venkatachalam Alterations in the charge and size selectivity barrier of the glomerular filter in aminonucleoside nephrosis in rats Lab Invest 44 1981 271 279
20. G.B. Ryan S.J. Hein M.J. Karnovsky Glomerular permeability to proteins. Effects of hemodynamic factors on the distribution of endogenous immunoglobulin G and exogenous catalase in the rat glomerulus Lab Invest 34 1976 415 427
21. G.B. Ryan M.J. Karnovsky Distribution of endogenous albumin in the rat glomerulus: Role of hemodynamic factors in glomerular barrier function Kidney Int 9 1976 36 45
22. C.E. Thomas P.D. Bell L.G. Navar Glomerular filtration dynamics in the dog during elevated plasma colloid osmotic pressure Kidney Int 15 1979 505 512
23. M.G. Farquhar S.L. Wissig G.E. Palade Glomerular permeability. I. Ferritin transfer across the normal glomerular capillary wall J Exp Med 113 1960 47 66
24. J.P. Caulfield M.G. Farquhar The permeability of glomerular capillaries to graded dextrans. Identification of the basement membrane as the primary filtration barrier J Cell Biol 63 1974 883 903
25. B.M. Brenner M.P. Bohrer C. Baylis W.M. Deen Determinants of glomerular permselectivity: insights derived from observations in vivo Kidney Int 12 1977 229 237
26. H.G. Rennke R.S. Cotran M.A. Venkatachalam Role of molecular charge in glomerular permeability. Tracer studies with cationized ferritins J Cell Biol 67 1975 638 646
27. R.L.S. Chang W.M. Deen C.R. Robertson B.M. Brenner Permselectivity of the glomerular capillary wall: III. Restricted transport of polyanions Kidney Int 8 1975 212 218
28. H.G. Rennke M.A. Venkatachalam Glomerular permeability: in vivo tracer studies with polyanionic and polycationic ferritins Kidney Int 11 1977 44 53
29. V.E. Kelley T. Cavallo Glomerular permeability. Ultrastructural studies in New Zealand black/white mice using polyanionic ferritin as a molecular probe Lab Invest 37 1977 265 275
30. V.E. Kelley T. Cavallo Glomerular permeability: transfer of native ferritin in glomeruli with decreased anionic sites Lab Invest 39 1978 547 553
31. R.C. Graham M.J. Karnovsky Glomerular permeability. Ultra-structural cytochemical studies using peroxidases as protein tracers J Exp Med 124 1966 1123 1134
32. M.A. Venkatachalam M.J. Karnovsky H.D. Fahimi R.S. Cotran An ultrastructural study of glomerular permeability using catalase and peroxidase as tracer proteins J Exp Med 132 1970 1153 1167
33. F. LaLiberte C. Sapin M.F. Belair P. Druet J. Bariety The localization of the filtration barrier in normal rat glomerulus by ultrastructural immunoperoxidase techniques Biol Cell 31 1978 15 27
34. Y.S. Kanwar M.G. Farquhar Isolation of glycosaminoglycans (heparan sulfate) from glomerular basement membranes Proc Natl Acad Sci USA 76 1979 4493 4497
35. Y.S. Kanwar M.G. Farquhar Presence of heparan sulfate in the glomerular basement membrane Proc Natl Acad Sci USA 76 1979 1303 1307
36. Y.S. Kanwar V.C. Hascall M.G. Farquhar Partial characterization of newly synthesized proteoglycans isolated from the glomerular basement membrane J Cell Biol 90 1981 527 532
37. M.C. Lemkin M.G. Farquhar Sulfated and nonsulfated glycosaminoglycans and glycopeptides are synthesized by kidney in vivo and incorporated into glomerular basement membranes Proc Natl Acad Sci USA 78 1981 1726 1730
38. T.C. Laurent In vitro studies on the transport of macromolecules through connective tissue Fed Proc 25 1966 1128 1133
39. W.M. Deen M.P. Bohrer B.M. Brenner Macromolecule transport across glomerular capillaries: Application of pore theory Kidney Int 16 1979 353 365
40. 125I-BSA Lab Invest 1982 (in press)
41. J.P. Caulfield M.G. Farquhar The permeability of glomerular capillaries of aminonucleoside nephrotic rats to graded dextrans J Exp Med 142 1975 61 83