Psoralen-containing sunscreen induces phototoxicity and epidermal ornithine decarboxylase activity

Journal of the American Academy of Dermatology

Volumn 6, Issue 6, 1982, Pages 1022-1027

  Walter, Joseph F ^a   Gange, Richard W ^a   Mendelson, I Robert ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 METHOXYCINNAMIC ACID 2 ETHYLHEXYL ESTER; BERGAMOT OIL; BERGAPTEN; ORNITHINE DECARBOXYLASE; PSORALEN; SUN SYSTEM III; SUNSCREEN; UNCLASSIFIED DRUG;

ADVERSE DRUG REACTION; ANIMAL EXPERIMENT; CARCINOGENESIS; EPIDERMIS; ERYTHEMA; INTOXICATION; MOUSE; PHOTOTOXICITY; SKIN; SKIN CANCER; TOPICAL DRUG ADMINISTRATION; ULTRAVIOLET RADIATION;

EID: 0020067104     PISSN: 01909622     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0190-9622(82)70086-6     Document Type: Article

References (21)

1. The chemistry of psoralens
2. 5-Methoxypsoralen (Bergapten) in photochemotherapy of psoriasis
3. Biochemical and medical aspects of psoralens
4. Photochemistry and photobiology of psoralens
5. The value of topical sunscreens containing psoralens
6. Epidermal ornithine decarboxylase, polyamines, cell proliferation, and tumor promotion
7. Ornithine decarboxylase in skin
8. Ultraviolet light induces epidermal ornithine decarboxylase activity
9. Ornithine decarboxylase and DNA synthesis in mouse skin treated with PU VA or anthracene + UVA
10. The induction of ornithine decarboxylase as an early, possibly obligatory, event in mouse skin carcinogenesis
11. Effects of 12-O-tetradecanol-phorbol-13-acetate and mezerein on epidermal ornithine decarboxylase activity, isoprotere nol-stimulated levels of cyclic adenosine 3′5′-monophosphate, and induction of mouse skin tumors in vivo
12. Ornithine decarboxylase activity, cell proliferation, and tumor promotion in mouse epidermis in vivo
13. Skin edema due to PUVA in the hairless mouse: Effects of antihistamines and indomethacin
14. Amine synthesis in rapidly growing tissues: Ornithine decarboxylase activity in regenerating rat liver, chick embryo and various tumors
15. The role of the induction of ornithine decarboxylase activity in tumor promotion
16. Ultraviolet light and epidermal polyamines
17. Lethal photosensitization of bacteria with 8-methoxypsoralen to long wavelength ultraviolet radiation
18. Photosensitivity
19. Photosensitized reactions and carcinogenesis
20. Risk of cutaneous carcinoma in patients treated with oral methoxsalen photochemotherapy for psoriasis
21. A comparison of the photocarcinogenic effects of 8-methoxypsoralen and 5-methoxypsoralen in hairless mice