Activity of organophosphorus insecticides in bacterial tests for mutagenicity and DNA repair - Direct alkylation vs. metabolic activation and breakdown. I. Butonate, vinylbutonate, trichlorfon, dichlorvos, demethyl dichlorvos and demethyl vinylbutonate

Chemico-Biological Interactions

Volumn 39, Issue 3, 1982, Pages 339-350

  Braun, R ^a   Schoneich J ^a   Weissflog, L ^b   Dedek, W ^b  

^a LEIBNIZ INSTITUTE OF PLANT GENETICS AND CROP PLANT RESEARCH IPK   (Germany)

^b Forschungsstelle für chemische Toxikologie der AdW der DDR ^*  (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DICHLORVOS; METRIFONATE;

ADVERSE DRUG REACTION; ALKYLATION; ANIMAL EXPERIMENT; BUTONATE; DNA DAMAGE; DNA REPAIR; DRUG COMPARISON; DRUG METABOLISM; ETIOLOGY; HEREDITY; IN VITRO STUDY; MUTAGENICITY; PROTEUS MIRABILIS; SALMONELLA TYPHIMURIUM;

ALKYLATING AGENTS; BIOTRANSFORMATION; DICHLORVOS; DNA REPAIR; INSECTICIDES, ORGANOPHOSPHATE; MUTAGENICITY TESTS; MUTAGENS; ORGANOPHOSPHORUS COMPOUNDS; TRICHLORFON;

EID: 0020057395     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/0009-2797(82)90050-3     Document Type: Article

References (31)

1. Mutagenicity studies of organophosphorus insecticides
2. Mutagenicity of organophosphorus compounds in bacteria and Drosophilia
3. Comparative mutagenicity studies with pesticides
4. Mutagenicity studies with pesticides in the Salmonella/microsome system
5. Zur Mutagenität von Dichloracetaldehyd und 2,2-Dichlor-1,1-dihydroxyäthanphosphonsäuremethylester, möglichen Metaboliten des phosphorganischen Pestizides Trichlorphon
6. Mutagenicity of dichlorvos and other structurally related pesticides in Salmonella and Streptomyces
7. 14C)-dichlorvos in the rat after oral and inhalation exposure
8. Zur Solvolyse von Demethyltrichlorphon
9. The mutagenicity of dichloroacetaldehyde
10. The mutagenic effect of 1,2-dichloroethane on Salmonella typhimurium. II. Activation by the isolated perfused rat liver
11. Activation of vinyl chloride to covalently bound metabolites: role of 2-chloroacetaldehyde
12. The alkylating properties of organophosphates
13. Metabolic activation of chlorinated ethylene derivatives
14. Multiple forms of rat liver glutathion-S-transferase: Specificity for conjugation of O-alkyl and O-aryl groups of organophosphorus insecticides
15. 32P-markierter phosphororganischer Insektizide und ihrer Vorprodukte
16. 32P-markierter Verbindungen
17. Repair-defective mutants of Proteus mirabilis as a prescreening system for the detection of potential carcinogens
18. Methods for detecting carcinogens and mutagens with the Salmonella/mammalian microsome mutagenicity test
19. Mutagenicities of N-nitrosamines on Salmonella
20. Microbiological mutagenicity studies of pesticides in vitro
21. Mutagenicity screening of pesticides in the microbial system
22. Mutagenicity of dichlorvos and methyl methanesulphonate for Escherichia coli WP2 and some derivatives deficient in DNA repair
23. 5-Methyltryptophan resistance in Escherichia coli. Mutagenic activity of monofunctional alkylating agents including organophosphorus insecticides
24. 32P-labelled butonate, trichlorfon and dichlorvos in crop plants
25. Studien zur Applikation und zum Metabolismus von Trichlorphon in der Veterinärmedizin
26. Effect of liver enzyme induction on paraoxon metabolism in the rat
27. Alkylation of guanine in mice in vivo by organophosphorus insecticedes. I. Trichlorphone and butonate
28. Formation of 7-methylguanine by dichlorvos in bacteria and mice
29. In vivo alkylation studies with dichlorvos at practical use concentrations
30. An evaluation of the genetic toxicity of dichlovos
31. Zur Reaktion von Phosphorsäurealkylestern mit 4-(4-Nitrobenzyl)pyridin (NBP)